Minor Salivary Gland Tumours: A Retrospective Study of Cases Treated in a Teaching Hospital, Kaduna, Nigeria | Chapter 12 | Medical Science: Trends and Innovations Vol. 13

Background: Tumours of the minor salivary glands occurring in the oral cavity are uncommon. The oral cavity has many tiny salivary glands, which occur in the lip, palate, floor of the mouth, cheeks, tongue and pharynx. Tumours could develop from any of these minor salivary glands. The tumours of the minor salivary glands have an insidious onset, oftentimes noticed when the tumour interferes with oral functions such as swallowing, speech, and breathing or when there are associated pains. The incidence of these tumours varies with age, sex and ethnicity.

 

Objective: The objective of this study is to investigate the nature, clinical features, pathology, and treatment of these tumours in North-West, Nigeria.

 

Materials and Methods: This was a retrospective study of all patients with minor salivary gland tumours that were treated at Barau Dikko Teaching Hospital, Kaduna, Nigeria. The study covered a period of eleven years from January 2009 to December 2019. Information was extracted from case files of patients. Data collected includes: age of patient at presentation, sex, location of tumour, clinical features, treatment, complications and histological diagnosis. Data obtained were analyzed using Statistical Package for Social Science (SPSS), version 20.0.

 

Results: The age of the patients ranged from 16 to 70 years, with the mean SD = 43.0 ± 6.6 years and the male-to-female ratio was 1:2. Benign tumours were the most common compared to malignancies. The palate was the commonest site of occurrence; followed by the upper lip. The treatment was surgical excision. Malignant cases received post-surgery chemotherapy and radiotherapy. Palatal fistula was the most common complication of the surgery.

 

Conclusion:  Pleomorphic adenoma was the most common tumour in this study.  Tumours in the palate interfere with oral functions and destroy maxillary bone resulting in untoward debilitating effects.

 

Author (s) Details

 

Omisakin Olatunde Oluleke
Department of Surgery, Dental/Maxillofacial Unit, Barau Dikko Teaching Hospital, Kaduna State University, Kaduna State, Nigeria.

 

Ayuba Iko Godwin
Department of Pathology and Forensic Medicine, Barau Dikko Teaching Hospital, Kaduna State University, Kaduna State, Nigeria.

 

Fomete Benjamin
Department of Dental Surgery, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.

 

Ogunsina Modupe
Department of Medicine, Barau Dikko Teaching Hospital, Kaduna State University, Kaduna State, Nigeria.

 

 

Sannom Yates
Department of Pathology and Forensic Medicine, Barau Dikko Teaching Hospital, Kaduna State University, Kaduna State, Nigeria.

 

Please see the book here:- https://doi.org/10.9734/bpi/msti/v13/4927

Advances in Understanding and Treating Oral Malignant Melanoma: A Comprehensive Review | Chapter 10 | Recent Updates in Disease and Health Research Vol. 2

Primary oral melanoma is an exceptionally uncommon and aggressive tumor that emerges from the mucosal epithelium of the oral cavity, particularly in the upper jaw (palate or alveolar gingivae). Malignant melanoma originating outside the skin is an exceedingly rare condition and is recognized as one of the most lethal neoplasms in humans. Oral malignant melanoma (OMM) constitutes approximately 1% of all melanomas and accounts for roughly 0.5% of all oral malignancies. OMM has been documented in individuals aged 20 to 80 years, with a higher incidence in males. Due to the typically painless nature of mucosal melanotic lesions in their early stages, delayed identification and subsequent treatment contribute to a poorer prognosis.

Author(s) Details:

Priya Devi,
Oral Pathology and Microbiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Sharon John,
Oral Pathology and Microbiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Shalini Gupta,
Oral Pathology and Microbiology, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Please see the link here: https://stm.bookpi.org/RUDHR-V2/article/view/13510

Histopathology of Nephrectomy Specimens in a Tertiary Care Hospital, India: A Review | Chapter 25 | New Horizons in Medicine and Medical Research Vol. 1

 This study was conducted retrospectively over a two-year period at the Department of Pathology at GMC Jammu to identify the Histopathological spectrum of illnesses detected in these collected nephrectomy tissues and compare it to other studies. A total of 70 nephrectomy specimens were obtained. Males made up 40 percent of the cases (57 percent), while females made up 30 percent (43 percent ). The cases ranged in age from three to seventy years. Patients between the ages of 41 and 50 had the highest percentage of patients. Non-neoplastic tumours were the most common (62 cases), followed by malignant tumours and benign tumours, with benign tumours being the least common. Chronic pyelonephritis was the most common inflammatory condition for which nephrectomy was performed (30 instances). Clear cell renal carcinoma was the most prevalent malignant tumour, with three incidences. Pain in the flanks was the most common clinical complaint. Non-neoplastic lesions outnumbered neoplastic lesions. Chronic pyelonephritis was the most prevalent histology diagnosis. Renal cell carcinoma was the most common type of malignant tumour.

Author(S) Details

Bharti Devi Thaker
Department of Pathology, GMC, Jammu, India.

Kailash Singh
Department of Surgery, GMC, Jammu, India.

View Book:- https://stm.bookpi.org/NHMMR-V1/article/view/6315

Clinical Presentation of Various Neck Masses: A Retrospective Study | Chapter 21 | Issues and Developments in Medicine and Medical Research Vol. 3

 The head and neck region is now included in the department of otorhinolaryngology. Any underlying condition in the head and neck area might cause a tumour in the neck. As a result, we will use this study to gain a more in-depth clinical understanding and approach to distinct neck masses. The importance of a timely diagnosis of a neck mass cannot be overstated, since delayed diagnosis leads to greater staging and a worse prognosis.

The goal of this study is to look at the clinical appearance of various neck masses as well as the clinical discrimination between malignant and non-malignant neck swellings.

Materials and Methods: From April 2012 to October 2013, a retrospective study was conducted in the department of ENT, MGMMC, MYH Indore, M.P., with a total of 190 patients with neck edoema. The numerous neck swellings had been thoroughly evaluated clinically, radiologically, and pathologically.

The incidence of malignant neck swelling rose with age, with 145 cases being non-malignant and 45 being malignant out of 190. Non-malignant swellings were linked to pain and fever in 32.1 percent and 90.4 percent of cases, respectively.

Conclusion: The methodical clinical examination of diverse neck masses resulted in accurate diagnosis and management of the patients, avoiding any delays or problems.


Author(S) Details

Jagram Verma
Department of ENT and Head and Neck Surgery, MGMMC and MYH, Indore (M.P), India.

Yamini Gupta
Department of ENT, Mahatma Gandhi Memorial Medical College and MYH Hospital, Indore, M.P, India.

N. Saraswathi
Department of ENT, Mahatma Gandhi Memorial Medical College and MYH Hospital, Indore, M.P, India.

View Book:- https://stm.bookpi.org/IDMMR-V3/article/view/5482

Differential Diagnosis of Focal Hepatic Lesions Using Ultrasound Confirmed with Histopathology: Recent Advancement | Chapter 3 | Highlights on Medicine and Medical Science Vol. 9

 Over the last few decades, advances in imaging technologies have helped to better characterise hepatic abnormalities. The goal of this study was to distinguish localised hepatic lesions based on ultrasound (U/S) features and compare the results to histology. A descriptive retrospective research of 100 patients with localised hepatic lesions was conducted at King Abdul-Aziz Specialist Hospital in Taif, Saudi Arabia, from 2012 to 2019. Adult Saudi patients aged 18 and up met the inclusion criteria. The investigation used LG-9 and Philips ultrasound equipment with 3.5 MHz transducers. The 55 to 80 year old age group accounted for 44% of the total, with a mean age of 49 years and 92 percent of married people. In histology, 86 percent of well-defined lesions margins were benign (p=0.00), 61 percent of ill-defined margin lesions were malignant (p=0.02), and 73 percent of hyperechoic lesions were hemangioma (p=0.02). When it came to the nature of hepatic lesions during U/S, 87 percent of solid lesions (p=0.03) were malignant, while 89 percent of cystic lesions were benign (p=0.03). Sixty-one percent of hypoechoic lesions were cancerous. Under colour Doppler, 80 percent of vascular lesions were benign. The sensitivity and specificity of the U/S test were 93.5 percent and 98 percent, respectively. U/S is a valuable tool for distinguishing cystic hepatic lesions from solid lesions in the liver. (p=0.03). To create a data base for hepatic lesions, comparable studies with large samples must be conducted in the Taif region. With a high degree of sensitivity and specificity, the majority of chosen hepatic lesions with suspicious characteristics were confirmed as malignant in histopathology.

Author(s) Details

Dr. Rania Mohammed Ahmed
Department of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif, KSA.

Ms. Sharifah Alkathiri
Department of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif, KSA.

Ms. Waad Altalhi
Department of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif, KSA.

Ms. Hatun Eid
Department of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif, KSA.

Ms. Manar Alshalawi
Department of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif, KSA.

Ms. Sara Alotaibi
Department of Radiological Sciences, College of Applied Medical Sciences, Taif University, Taif, KSA.

View Book :- https://stm.bookpi.org/HMMS-V9/article/view/2237