Showing posts with label in vivo. Show all posts
Showing posts with label in vivo. Show all posts

Thursday, 20 July 2023

A Cytogenetic Overview of Bulgarian Rosa alba L. Essential Oil, Hydrosol and Wastewater – Generated by Water-Steam Distillation on in vivo and in vitro Test-Systems| Chapter 4 | Novel Aspects on Chemistry and Biochemistry Vol. 4

 The main object concerning this overview search out present our investigations on the safety evaluation and some organic activities of the Rosa alba L. products (essential lubricate, hydrosol, and wastewater discarded all along oil distillate) based on the results obtained on three types of test-wholes: plant test-system, animal test-plan in vivo, and human lymphocytes in vitro. The harmless use of aforementioned natural commodity is essential because of their main role in various circles of human life - drugstore, cosmetics, food manufacturing, and others. For this purpose, the organic activity of the particular products must be determined. To get more detailed facts about the specific effects of the commodity tested, a complex of cytogenetic tests was secondhand, and various concentrations were proven, applying different exploratory schemes.The results bestowed here, show that R. alba L. essential oil, allure hydrosol, and wastewater did not seize high cytotoxic and genotoxic exercises. These effects depended on the synthetic components of each red-pink product, the concentrations applied, and the sense of the test-system secondhand. The tested red-pink products (essential oil and wastewater) have cytoprotective and genoprotective potential against the direct alkylating power MNNG.Data are promising and show that these everyday products are good candidates for further use indifferent sectors of human existence.

Author(s) Details:

Gabriele Jovtchev,

Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.

Svetla Gateva,

Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.

Tsvetelina Gerasimova,

Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.

Margarita Topashka-Ancheva,

Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.

Tsveta Angelova,

Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.

Alexander Stankov,

Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin Str., 1113 Sofia, Bulgaria.

Ana Dobreva,

Institute for Roses and Aromatic Plants, Agricultural Academy, 49 Osvobojdenie Blvd., 6100 Kazanlak, Bulgaria.

Milka Mileva,

The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.

Please see the link here: https://stm.bookpi.org/NACB-V4/article/view/11255

Friday, 26 May 2023

Amines Mimic Insulin In Vitro and In Vivo: Acceleration of Cellular Glucose Consumption | Chapter 6 | New Advances in Medicine and Medical Science Vol. 2

 The study has been designed to expand new anti-diabetes drugs. Defects in insulin secretion in vivo bring about hyperglycemia, type 1 diabetes mellitus (DM), and either insufficient insulin secretion or insulin fighting, which induces type 2 DM. Even though several anti-type 2 DM drugs are possible, to our knowledge, anti-type 1 DM drugs destitute been developed. Amines have existed studied as candidate drugs against type 1 DM, cause other basic compounds, to a degree carbonates (NaHCO3 and NaCO3), accelerate glucose use in cultured containers. We evaluated more than 20 synthetic compounds, including pharmacological drugs, in cultured containers. Among these, 2-amino-1-phenylethanol (2-A-1-PET) and 2-amino-N-cyclohexylethanol (2-A-N-CET) considerably accelerated glucose use, which was followed by usually from breast production in containers. Moreover, treatment accompanying 2-A-1-PET reduced sweet substance levels in rats. In cells, both 2-Excellent-PET and 2-A-N-CET abolished the effects of DM-encouraging drugs, such as streptozotocin and alloxan, and nicotinamide, on glucose devouring, whereas both 2-Excellent-PET and 2-A-N-CET exerted supplement effects with vanadium, carbonates, or concanavalin A on level of glucose in blood consumption.

Author(s) Details:

Kenji Sorimachi,
Bioscience Laboratory, Environmental Engineering Co., Ltd., Takasaki, Gunma, Japan.

Please see the link here: https://stm.bookpi.org/NAMMS-V2/article/view/10624

Tuesday, 19 October 2021

Study on Evaluation of the Efficacy of Different Fungicides against Fusarium musae, a Fruit Rot Disease of Banana | Chapter 10 | New Visions in Biological Science Vol. 4

 Due to the paucity of research on fusarium fruit rot diseases of banana and their management in India, it is thought worthwhile to conduct research on fusarium fruit rot diseases of banana and their management in south Gujarat in order to extend the shelf life of banana fruits and reduce losses caused by post-harvest diseases. As a result, the current investigation was launched. In this study, nine fungicides were tested against F. musae using the poison food technique on PDA medium at various concentrations. Mancozeb 75 WP at 2500ppm, azoxystrobin (20%) + difenoconazole (12.5%) at 1000ppm, and propiconazole (25 EC) at 500ppm and 1000ppm were found to be the most superior because they completely inhibited F. musae mycelial growth In vivo, the lowest fusarium fruit rot severity was found with propiconazole (25 EC) at 1000ppm in pre (6.61 percent) and post-inoculation (6.7 percent) treatments at 8 days after inoculation in pre (6.61 percent) and post-inoculation (6.7 percent) treatments at 8 days after inoculation. At 8 days after inoculation, azoxystrobin (20%) + difenoconazole (12.5%) at 500ppm and chlorothalonil (75 WP) at 2500ppm were shown to be the least efficient in decreasing the severity of fusarium fruit rot in pre and post inoculation treatments.

Author(S) Details

Tushar T. Baria
Department of Plant Pathology, N. M. College of Agriculture, Navsari Agricultural University, Navsari, Gujarat, 396 450, India.

View Book:- https://stm.bookpi.org/NVBS-V4/article/view/4302

Tuesday, 5 October 2021

Rational Evaluation of Bone Grafts for Different Intraosseus and Heterotopic Implantations in Various Animal Models | Chapter 3 | New Approaches in Engineering Research Vol. 15

 The complicated process of bone fracture healing includes inflammation, repair, and remodelling. Bone grafts or even bone material substitutes should be used to treat impaired bone repair. Before being used in patients, these bone material substitutes must be evaluated in vitro and in vivo. Various large and small animal models have been used to test various intraosseous and heterotopic bone replacement implants. For the most part, bone substitutes are evaluated orthotopically. However, prior to using large animal osseous defect models, literature advocates starting with small animals. The most widely used flaws sites for implantation in rat and rabbit models are the calvaria and femur, but crucial size defects vary greatly between animals. After the implantation of a bone substitute, heterotopic ossification can be detected in all mammals. The implantation of bone granules, on the other hand, most often does not result in the development of new bone-like tissue in small animals, but only in large mammals. The implantation of bone substitute blocks, on the other hand, does result in the formation of new bone-like tissue in both small and large animals. Chapter locations for implantation of bone substitutes and animal bone deficiency models are critically assessed in this book, with recommendations for future research.


Author(S) Details

Christian Weinand
Sektion Plastic, Aesthetic and Reconstructive Surgery, Hand Surgery Klinikum Osnabrück, Germany.

View Book:- https://stm.bookpi.org/NAER-V15/article/view/4022

Saturday, 12 June 2021

A Detailed Study of Pesticide Induced Puffs in Chironomus striatipennis | Chapter 7 | Recent Research Advances in Biology Vol. 8

 Because of their efficiency against a wide range of insect pests, pesticides are widely employed. It has an effect on the aquatic vegetation and fauna. The current study looks at the acute toxicity of endosulfan to 4th instar larvae of Chironomus stratipennis, a common and widespread Indian species. For analysing polytene chromosomal band maps and puffing activity, Chironomus stratipennis is a good research instrument. There is a scarcity of data on the biology, band maps, and puffing activity of Maharashtra's species, notably in the Nasik region. The current study looked at normal puffing of fourth instar larvae and puff induction after pesticide exposure in vivo and in vitro in Chironomus striatipennis from the Nasik region. In vivo, endosulfan-induced puff was seen in the 13A and 14C areas of the III chromosome arm, as well as the 14C area in vitro.

Author (s) Details

Patil Mayura S.
Department of Zoology, KSKW Art Science and Commerce College, Nasik-422008, (M.S.), India.

View Book :- https://stm.bookpi.org/RRAB-V8/article/view/1202