Diabetes and Cancer Associated Complications | Chapter 26 | Socio-Scientific Interaction in Diabetes and Cancer and Its Management

 Diabetes and cancer are most prevalent chronic diseases worldwide. Studies have shown that there is a strong association between diabetes and an increased risk of cancer, as well as of mortality. The purpose of this review article is to be aware means the risk of association between diabetes and cancer and the steps to prevent it by medication and other because studies still obscure whether diabetes leads to cancer or cancer causes diabetes.

Author(s) Details:

Vinita Singh,
Department of Zoology, C.M. Science College, Darbhanga-846004, Bihar, India.

Please see the link here: https://stm.bookpi.org/SSIDCIM/article/view/12744

Hepatitis B Virus Infection and MicroRNAs: Future Trends to Diagnostics and Therapeutics | Chapter 11 | Research Aspects in Biological Science Vol. 2

 Hepatitis B virus (HBV) infects the liver and causes acute and chronic sickness, which can progress to severe end-stage liver disease. Despite the availability of an effective vaccination and a variety of treatment options, this virus remains the leading cause of liver disease, accounting for a significant portion of global morbidity and death. The significance of miRNAs, which are essential modulators of gene activity, in the control of Hepatitis B virus gene expression has been widely studied. Facilitation, direct or indirect inhibition, immune response activation, epigenetic modulation, and a variety of other mechanisms can all be used to control viral reproduction and pathogenicity. There are certain miRNAs that engage in more than one of these processes among the many miRNAs involved in each of these mechanisms. The current chapter is an attempt to categorise these miRNAs effectively from a functional standpoint. A thorough understanding of miRNAs and their methods for changing the virus and/or the host might aid in the future development of numerous diagnostic and therapeutic techniques. Sarkar et al. published the findings of this chapter in the International Journal of Molecular Sciences in 2015.

Author(S) Details

Neelakshi Sarkar
ICMR Virus Unit, Kolkata, ID & BG Hospital Campus, Kolkata, India

Runu Chakravarty
Virus Unit, Kolkata, ID & BG Hospital Campus, Kolkata, India.

View Book:- https://stm.bookpi.org/RABS-V2/article/view/6711

Report on the Cryptococcal Meningitis in Patient with Chronic Myeloid Leukemia | Chapter 5 | Current Topics in Medicine and Medical Research Vol.5

 

This study aimed to report the case of a female patient with chronic myeloid leukemia affected by
cryptococcal meningitis. ML, white, 48 years old, female sex, previously diagnosed with chronic
myeloid leukemia that has been refractive to the use of imatinib and who has recently begun using
nilotinib, was admitted complaining of sudden and disabling migraine in the last 1 month associated
with asthenia, adinamia, anorexia, disinterest for daily activities, dizziness, nausea, and vomiting. She
evolved with ataxia, and started to stroll with help and showed decrease of muscular strength in her
upper limbs. The cerebrospinal fluid showed presence of Cryptococcus sp. and, therefore, we began
treatment with intravenous liposomalamphotericin B in the dose of 3 mg/kg/day, for 6 weeks. A new
cerebrospinal fluid analysis, at the end of treatment, also showed rare structures that are compatible
with Cryptococcus sp. After stabilization and clinical improvement, she was discharged. After 3
weeks, she was hospitalized again with degeneration of the condition, and died due to intracranial
hypertension secondary to cryptococcal infection. This report reinforces the need of reflecting on fungi
pathologies, especially in immunosuppressant patients, as well as the importance of early diagnosing
and making a fast intervention, with the aims of providing quality of life and comfort to the patient and
of minimizing neurological sequelae to the patient.

Author (s) Details

Ricardo Parente Garcia Vieira
School of Medicine, Universidade Federal do Cariri, Barbalha, Brazil.

Jucier Gonçalves Júnior
Medical Residency Program in Internal Medicine, Santa Casa de Misericórdia de Fortaleza, Fortaleza, Brazil.

Acácio Vieira Machado Leite
School of Medicine, Universidade Federal do Cariri, Barbalha, Brazil.

Viviane Chaves Pereira
School of Medicine, Universidade Federal do Cariri, Barbalha, Brazil.

Nélio Barreto Vieira
School of Medicine, Universidade Federal do Cariri, Barbalha, Brazil.

Modesto Leite Rolim-Neto
School of Medicine, Universidade Federal do Cariri, Barbalha, Brazil.

View Book:- https://bp.bookpi.org/index.php/bpi/catalog/book/270