Striking the Balance: Navigating the Complexities of Intrauterine Infection and Inflammation (Triple I) for Better Maternal and Neonatal Outcomes | Chapter 10 | Disease and Health: Research Developments Vol. 5

Intrauterine infection, inflammation or both (Triple I) is known to cause detrimental pregnancy outcomes. On one hand delay in the diagnosis of chorioamnionitis can potentially cause adverse pregnancy outcomes, on the other hand, over-diagnosis leads to inapt antibiotic use, prolonged neonatal intensive care unit (NICU) stay, disruption of mother-infant bonding, delays in breastfeeding, economic burden and emotional stress from the prolonged hospital and NICU stay. In the literature, many studies and reviews have discussed Triple I in detail. However, many issues with diagnosis and management remain unclear. This narrative review gives an insight into  these issues and will aid not only in the diagnosis but also in the management of Triple-I.

 

Author (s) Details

 

Sufia Athar
Al Wakra Hospital, Hamad Medical Corporation, Qatar and Qatar University, Qatar.

 

Sarfaraz Abedin
Al Wakra Hospital, Hamad Medical Corporation, Qatar.

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrd/v5/4277

Assessing the Clinical Profile of Malaria and It’s Complications in Magadh Zone of Bihar, India | Chapter 10 | Current Overview on Disease and Health Research Vol. 1

The goal of the current study was to assess the clinical profile and its complications that aid in early malaria recognition and prompt treatment, thereby lowering morbidity and mortality.

One of the most frequent causes of fever and other associated human misery is still malaria. It continues to be a significant burden for tropical nations despite ongoing prevention initiatives. Despite being nearly eradicated from many nations, including the United States, Canada, Europe, and Russia, malaria has recently presented new challenges in terms of changing clinical profiles and management, particularly p. vivax infection, which is frequently found to cause severe malaria and, contrary to popular belief, defies early detection and timely antimalarial medication.

From the indoor and outdoor sections of the Magadh Medical College Hospital in Gaya, a total of 96 patients were enrolled. Rapid testing and a peripheral blood smear examination are used to identify malaria. A comprehensive clinical examination was conducted, and both regular and specialised lab tests were run. Current clinical features were also documented. A thorough examination was done, the right therapy was given, and frequent follow-up was done. Serious malaria was defined according to WHO standards.

54 percent were infected with vivax, 47 percent with P. falciparum, and 9 percent with mixed illness. More than 30% of individuals exhibited atypical clinical characteristics, 8.6% showed warning signals, and 31% experienced severe malaria. In contrast to common belief, P. vivax also experienced problems.

Early diagnosis is the key to reducing morbidity and death. Typical but deceptive clinical symptoms include cough, severe headache, severe myalgia, diarrhoea, stomach pain, severe arthralgia, oliguria, and malena. Unusual symptoms were seen in a large majority of the individuals in this group.

In India, different regions have different rates of malaria as well as different ratios of p. vivax and p. falciparum. P. vivax is the dominating species in the Magadh zone of Bihar. Malaria is still a significant problem for public health. P vivax's altered clinical profile and increased pathogenicity have drawn attention. Understanding these traits enables early detection and improves results.

Author (s) Details:

Pramod Kumar Sinha,
Department of Medicine, Anugrah Narayan Magadh Medical College Hospital , Gaya-823001 (Bihar), India.

S. N. Singh,
Department of Medicine, Anugrah Narayan Medical College Hospital, Gaya, (Bihar), India.

Deo Chaudhary,
Department of Medicine, Anugrah Narayan Medical College Hospital, Gaya, (Bihar), India.

Please see the link here: https://stm.bookpi.org/CODHR-V1/article/view/7430 

Study on Subjective Complaints of Malaria Related to Muscles and Joints| Chapter 9 | Highlights on Medicine and Medical Science Vol. 11

 Malaria is still a huge health problem around the world that has yet to be solved. Like an iceberg, WHO stated in their 2020 report that while there were advancements at the beginning of the third millennium, there has been a plateau in the last three years (since 2017) that appears to have hampered efforts to eradicate global malaria. In certain communities engulfed in war and poverty, access to medical services and effective treatment remains an issue. Aside from that, persistent endemic areas combined with global and/or regional migration of susceptible individuals to and from endemic areas raises the risk of morbidity and mortality. Malaria causes a wide range of symptoms, including the classic trias of fever, anaemia, and splenomegali. Muscle and joint discomfort, a disease associated to parasite-induced inflammation, is another symptom that patients may experience. If the pain persists throughout the duration of the illness, it's likely that you're suffering from rhabdomyolisis, a potentially catastrophic and devastating clinical condition classified as a consequence of malaria or severe malaria. The patient's condition may deteriorate and become fatal if effective antimalaria medication is not received.

Author (s) Details

Forman Erwin Siagian
Department of Parasitology & The Centre of Biomedic Research, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta, Indonesia.

View Book :- https://stm.bookpi.org/HMMS-V11/article/view/2502

Determination of Eruptive Fevers in the Infectious Diseases Department of Ouagadougou CHU-YO, Burkina Faso from 2005 to 2019 | Chapter 10 | Highlights on Medicine and Medical Science Vol. 9

 Infectious cutaneous diseases are a major public health issue in tropical environments. In the Infectious Diseases Department of CHU YO, describe the epidemiological, clinical, therapeutic, and evolutionary aspects of eruptive fevers. Patients and Procedures: The research took place at the Yalgado Ouedraogo University Hospital Center's Department of Infectious and Tropical Diseases. From January 1, 2005, to December 31, 2019, a descriptive retrospective analysis of cases of eruptive fever hospitalised in the department was conducted. Eruptive diseases were found to be prevalent in 5% of the population over the study period. Patients ranged in age from one to seventy-three years old on average. With a sex ratio of 1.4, the most represented age group was 01- 14 years old (53.1 percent). Only 27.2 percent of patients had had their measles vaccination. The most common syndrome was a combination of fever and cough (26.2 percent ). Maculopapular lesions were the most common elemental lesions (46.2%), followed by vesicular lesions (10 percent ). Measles (50.8 percent), herpes (19.2 percent), chickenpox (14.6 percent), HIV infection (6.3 percent), and meningitis were the most common pathologies involved (6.1 percent ). Hospitalization lasted an average of 7.5 days, with extremes of 1 and 26 days. The fatality rate was 4.6%. Conclusion: Measles and chickenpox are still causing outbreaks in Burkina Faso communities. It is critical to raise immunisation awareness against these febrile eruptive illnesses.

Author(s) Details

Dr. Savadogo Mamoudou
Department of Infectious Diseases, Yalgado Ouedraogo University Hospital, and UFR / SDS of Joseph Ki Zerbo University, Burkina Faso.

Diallo Ismaël
Internal Medicine Department, Yalgado Ouédraogo University Hospital, and UFR / SDS of Joseph Ki Zerbo University, Burkina Faso.

Sondo K. Apoline
Department of Infectious Diseases, Yalgado Ouedraogo University Hospital, and UFR / SDS of Joseph Ki Zerbo University, Burkina Faso.

View Book :- https://stm.bookpi.org/HMMS-V9/article/view/2244