Background: Pregnancy-induced hypertension and Foetal growth restriction are very common complications associated with pregnancy. UAPI may become an early predictor for complications, and early intervention may substantially reduce these complications.
Aims: Role of uterine artery doppler and low dose aspirin
intervention on fetomaternal outcome in low-risk pregnant women.
Objectives
·
Prevalence of women with high UAPI in a low-risk
pregnant woman.
·
To study the role of aspirin in women with high
UAPI.
·
To compare pregnancy outcomes in women with
normal UAPI and those with high UAPI started on aspirin.
·
To establish the role of UAPI as a recommended
screening test for improving feto-maternal outcome.
Study Setting and Design: A Prospective, Observational,
Analytical study was conducted over a period of 2 years at a tertiary care
hospital in western India.
Methods: The present study was carried out on 64 low-risk,
primi, singleton pregnant women from the routine antenatal clinic at Ruby Hall
Clinic, Grant Medical Foundation, Sassoon Road, Pune. Patients were divided
into a study group and a control group. Study group population underwent UAPI
measurement at 11- 13+6 weeks of pregnancy along with routine NT – NB scan.
Patients with high UAPI were given 150 mg of aspirin. Complication markers were
observed and compared with the control group
Results: Overall incidence of preeclampsia and FGR in study
group is less, (preeclampsia in study group 12.5% Vs 21.8% in control group
& FGR 9.3% in study group Vs 18.75% in control group) attributed by
prediction of feto-maternal outcomes by UAPI value (uterine artery Doppler
changes) and early intervention with low dose aspirin (150 mg). While in the
control group without uterine artery Doppler study and without intervention
incidence of preeclampsia and FGR is on the higher side.
Conclusion: Uterine artery doppler at 11- 13th week of
pregnancy is instrumental to predict late onset complications and should be
included in routine antenatal investigation irrespective of risk factor.
Pregnancy-induced hypertensive complications and foetal growth restriction in
patients with high UAPI can be reduced by low-dose aspirin.
Author (s) Details
Dr. Rashmi Bala Patel
MBBS, DNB (Obstetrics and Gynecology), Assistant Professor, AIIMS Kalyani,
India.
Dr. Vineeta Singh
MBBS, MS (Obstetrics and Gynecology), MRCOG, DNB, Associate Professor,
AIIMS, Deoghar, India.
Dr. Ajay Kumar Patel
MBBS, MS (Anatomy), Associate Professor, AIIMS, Deoghar, India.
Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49970-92-2
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