Introduction:
Panchavalkal is a well-known Ayurvedic poly-herbal formulation that has been
reported to be used against inflammation, cleaning ulcers, and other types of
wounds. Wounds affect a large proportion of the population worldwide most
especially children in rural areas. However, little attention is always given
to this health concern. In the experiment, one group received sesame oil to act
as a positive control, another group received no intervention, acting as a
negative control, while the remaining two groups received Panchavalkal ointment
as treatment groups.
Aims and Objectives:
To investigate the wound healing activity of Panchavalkal ointment on
mechanically induced wounds in Wistar rats.
Material and Methods:
Wistar strain albino rats of both sexes weighing 180 to 220g were used for the
experiment. The rats were divided into four groups each consisting of six rats.
A total of 24 rats were used for the whole study.
Statistical Analysis:
One way analysis of variance (ANOVA) was used to compare the mean values of
quantitative variables among the groups followed by Dunnett’s multiple ‘t’
test.
Observations and
Results: Sesame oil and Panchvalkal ointment showed almost similar wound
healing effects in comparison to control group which received no intervention.
Discussion: Panchavalkal
ointment showed a statistically highly significant percentage of contraction of
the excision wound area as compared to the negative control. Epithelization
period was significantly decreased in sesame oil and Panchavalkal ointment
(treatment groups).
Conclusion:
Panchavalkal ointment decreased the pain, tenderness, redness, and swelling of
the wounds which helped to control infection on the wounds and enhanced the
rate of wound healing in albino rats. Therefore Panchavalkal ointment has
anti-inflammatory, antibacterial and wound-healing properties.
Author(s)details:-
Vaikhari Dhurve
Department of Shalya Tantra, IPGT&RA, Gujarat Ayurved University,
Jamnagar, Gujarat, India.
Pravin Jawanjal
Department of Rasa Shastra and Bhaishajya Kalpana, IPGT&RA, Gujarat
Ayurved University, Jamnagar, Gujarat, India.
Mukesh Naria
Department of Pharmacology Laboratory, Institute for Postgraduate Teaching
and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India.
Tukaram Dudhamal
Department of Shalya Tantra IPGT&RA, Gujarat Ayurved University,
Jamnagar, Gujarat, India.
Please See the book
here :- https://doi.org/10.9734/bpi/prrat/v2/141
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