An Overview on Sintering Technique in Pharmaceutical Sciences | Chapter 11 | Advanced Concepts in Pharmaceutical Research Vol. 9

 Sintering is the mechanism that strengthens the mechanical properties of consolidated pharmaceutical powders at high temperatures, forms solid bonds during tablet compression, and causes thermal curing in polymer-latex film coatings, according to pharmaceutical science. The concept of sintering was applied in the investigation of the effect of heating on the mechanical properties of pharmaceutical powders. The formation of solid bonds within a powder bed during tablet compression was studied in terms of sintering. The sintering process has been used for the fabrication of sustained–release matrix tablets and for the stabilization of the drug permeability of film coatings derived from various pharmaceutical lattices.  Drug release characteristics from the sintered matrix tablets were inversely related to the sintering temperature and sintering duration. As the temperature of sintering and duration of sintering increased, the time required to attain maximum release from tablets also increased accordingly. The changes in the microstructures, hardness, friability, wettability, disintegration time and dissolution rate of tablets stored at elevated temperatures were also described as a result of sintering. Sintering conditions markedly affected the drug release properties depending upon the duration and temperature of sintering. The use of this sintering technique adds to the effectiveness of polymers for controlling drug release and provides a significant and expedient method for control release in oral dosage form.

Author(s) Details:

Dr. Chandan Mohanty
Guru Nanak Institutions Technical Campus-School of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India.

Mrs. Soumya Stuti Patnaik
Guru Nanak Institutions Technical Campus-School of Pharmacy, Ibrahimpatnam, Hyderabad-501506, Telangana, India.

Please see the link here: https://stm.bookpi.org/ACPR-V9/article/view/14370

Structural Changes in UHMWPE Reactor Powders during Sintering under Different Conditions| Chapter 9 | New Trends in Physical Science Research Vol.3

The change in the structure of the ultra-high-molecular-weight polyethylene (UHMWPE) nascent reactor powder during sintering at various temperatures and pressures was examined using the DSC method to elucidate the effect of processing parameters on the structure. Scanning electron microscopy revealed that the primary morphological units of the UHMWPE reactor powder investigated are crystalline lamellae. Because the heat flux dH/dT (where H is the melting enthalpy and T is the sample temperature) is proportional to the mass fraction of lamellae melting at a given temperature, data on the thickness distribution of the lamellae could be obtained by analysing the shape of the polymer melting peak on the DSC curves. The structure of UHMWPE has not yet been subjected to such scrutiny. The proportion of thick (>15 nm) and thin (10 nm) lamellae in compacted samples and those sintered at a temperature of 130oC (lower than the equilibrium melting temperature of an infinitely long polyethylene crystal T0 = 142oC) is found to be virtually identical. Significant variations in the composition of the lamellae of various thicknesses have been observed in the samples sintered at temperatures above the T0 of PE with subsequent cooling under various circumstances. At the same time, their melting points remained unaltered when the samples were heated from 130°C to 145°C while under pressure.

Author(s) Details:

L. P. Myasnikova,
IOFFE Institute, 26 Polytechnicheskaya, St. Petersburg 194021, Russia.

A. K. Borisov,
IOFFE Institute, 26 Polytechnicheskaya, St. Petersburg 194021, Russia.

Yu. M. Boiko,
IOFFE Institute, 26 Polytechnicheskaya, St. Petersburg 194021, Russia.

A. P. Borsenko,
A. A.Galkin Physical-Technical Institute, str. R. Luxemburg 72, Donetsk, 83114, Ukraine.

V. F. Drobot’ko,
A. A.Galkin Physical-Technical Institute, str. R. Luxemburg 72, Donetsk, 83114, Ukraine.

V. M. Egorov,
IOFFE Institute, 26 Polytechnicheskaya, St. Petersburg 194021, Russia.

E. M. Ivankova,
Institute of Macromolecular Compounds, 31 Bolshoy pr., St. Petersburg 199004, Russia.

E. I. Radovanova,
IOFFE Institute, 26 Polytechnicheskaya, St. Petersburg 194021, Russia.

V. A. Marikhin,
IOFFE Institute, 26 Polytechnicheskaya, St. Petersburg 194021, Russia.

Please see the link here: https://stm.bookpi.org/NTPSR-V3/article/view/6828

Mechanical Characterization of Potassium and Hydroxyl Bearing Fluorapatite Bioceramics: A Brief Overview | Chapter 11 | New Innovations in Chemistry and Biochemistry Vol. 5

 The researchers looked at palladium (II) complex compounds that had been adsorbed on the dry inner surface of nano-porous silicate glass. The spectral reaction of solid specimens containing Pd(II) salts and organic complexes on carbon monoxide in the environment was manufactured and examined. While reacting with carbon monoxide, the specimens showed subtle and reversible colour changes. The creation and dissociation of coordination compounds on the nano-porous glass inner surface are thought to be involved in the reaction mechanisms. The research findings could be used in chemical sensors to detect carbon monoxide in the atmosphere, according to the researchers. The processes were given a chemical explanation.

Author(S) Details

Jihen Ben Slimen
Unit Research of Electrochemistry, Materials and Environment, Faculty of Sciences, Gabes University, Erriadh City 6072, Tunisia.

Samira Jebahi
Energy and Matter Research Laboratory, National Center of Sciences and Nuclear Technology, Technological pole, 2020, Sidi Thabet, Tunisia.

Sergey V. Dorozhkin
Kudrinskaja sq. 1-155, 123242 Moscou, Russie.

Khaled Boughzala
RU Analysis and Applied Process for Environment, High Institute of Applied Sciences and Technologies, 5121 Mahdia, Tunisia.

Mustapha Hidouri
Unit Research of Electrochemistry, Materials and Environment, Faculty of Sciences, Gabes University, Erriadh City 6072, Tunisia and High Institute of Applied Sciences and Technology, Gabes University, Omar Ibn Khattab Road, 6029, Gabes, Tunisia.

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An Investigation of Thermodynamic Prehistory in the Formation of the Internal Structure of Highly Stable Ferroelectric Materials | Chapter 4 | Current Approaches in Science and Technology Research Vol. 7

 We investigated and presented our findings for the dependence of the crystalline and grain structure characteristics of the PCR-13 material (based on the lead zirconate titanate (PZT) system) sintered in various ways on the regulations for its preparation. The data from the surface microfluorescence analysis of ceramic materials were provided, allowing us to state that micro X-ray fluorescence spectrometry (MICRO–XRF), We can trace even minor changes in the chemical composition of ceramic samples, characterize the degree of surface homogeneity reliably, and provide strict mathematical conclusions about the reproducibility of the properties of manufactured piezoelectric ceramic materials when combined with mathematical statistics. The optimal conditions for ceramics have been selected based on the obtained data, ensuring homogeneity, high-density structure, and reproducibility of the characteristics. This enables us to use the material in frequency-selective equipment with confidence. The most homogeneous (perfect) structure has been discovered to be realized using conventional ceramic technology.

Author (S) Details

Konstantin P. Andryushin
Research Institute of Physics, Southern Federal University, Rostov-on-Don 344090, Russia.

Inna N. Andryshina
Research Institute of Physics, Southern Federal University, Rostov-on-Don 344090, Russia.

Lidiya A. Shilkina
Research Institute of Physics, Southern Federal University, Rostov-on-Don 344090, Russia.

Svetlana I. Dudkina
Research Institute of Physics, Southern Federal University, Rostov-on-Don 344090, Russia.

Iliya A. Verbenko
Research Institute of Physics, Southern Federal University, Rostov-on-Don 344090, Russia.

Larisa A. Reznichenko
Research Institute of Physics, Southern Federal University, Rostov-on-Don 344090, Russia.

Mihail I. Mazuritskiy
Department of Physics of Nano-systems and Spectroscopy of the Physics Faculty, South Federal University, Rostov-on-Don 344090, Russia.

Alexandr V. Nagaenko
Research and Design Bureau “Piezopribor”, South Federal University, 344090 Rostov-on-Don, Russia.

Ivan A. Parinov
I. I. Vorovich Mathematics, Mechanics and Computer Sciences Institute, Southern Federal University, Rostov-on-Don 344090, Russia.

Shun-Hsyung Chang
National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.

Hung-Yu Wang
National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.

View Book :-  https://stm.bookpi.org/CASTR-V7/article/view/1814

A Detailed and Comparative Study on Conventional Sintering with Microwave Sintering and Vacuum Sintering of Y2O3-Al2O3-ZrO2 Ceramics | Chapter 12 | Current Perspectives on Chemical Sciences Vol. 6

 This chapter focused on comparative studies on conventional, microwave and vacuum sintering of alumina-added stabilised zirconia yttria (YSZ). When energy and time savings are involved, microwave sintering has been found to be the most effective sintering technique. In contrast to the conventionally sintered ones, microwave and vacuum sintered specimens display improved densification at lower temperatures. In contrast to the traditional and vacuum sintered specimens, the microwave sintered specimen displayed the highest hardness. In addition, it was found that the size of the particle had a prominent role in regulating densification enhancement.

Author(s) Details

Mayur Shukla
Academy of Scientific and Innovative Research (AcSIR), CSIR-Central Glass and Ceramic Research Institute, Kolkata, India and CSIR-Central Glass and Ceramic Research Institute (CSIR-CGCRI), Kolkata, India.

Sumana Ghosh
CSIR-Central Glass and Ceramic Research Institute (CSIR-CGCRI), Kolkata, India.

Nandadulal Dandapat
CSIR-Central Glass and Ceramic Research Institute (CSIR-CGCRI), Kolkata, India.

Ashis K. Mandal
CSIR-Central Glass and Ceramic Research Institute (CSIR-CGCRI), Kolkata, India.

Vamsi K. Balla
CSIR-Central Glass and Ceramic Research Institute (CSIR-CGCRI), Kolkata, India.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/355