Pre-Articular and Explosive form of Rheumetoid Arthritis in a Mongel Dog | Chapter 10 | Innovations in Biological Science Vol. 4

A case of an active-explosive form of Rheumatoid arthritis with poly-arthritis was presented in a mongrel male dog. The same was brought six months back with a pre-articular/ subclinical form with predominate signs of anemia but no lameness. On the basis of its past and present history, clinical examination and hematology, it was diagnosed as a case of flare of active and explosive form of Rheumatoid arthritis. Its etiology, pathology, management and treatment with DMARDs and corticosteroids were discussed.

 

 

Author(s) Details

Arvind Sharma

Animal Husbandry, Gurdaspur, Punjab, India.

Kiran Preet Kaur

Veterinary Polyclinic, Gurdaspur, Punjab, India.

Sham Singh

Animal Husbandry, Gurdaspur, Punjab, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/ibs/v4/4165C

A Case Study of Inflammatory Arthritis with Progressive Joint Destruction | Chapter 11 | Medical Science: Recent Advances and Applications Vol. 3

Rheumatoid arthritis is a systemic inflammatory disease with autoimmune features, with a predominant expression in peripheral synovial joints.  A clinical evaluation remains the cornerstone for evaluating early arthritis; determining whether arthritis is present or not, differentiating between the inflammatory or non-inflammatory disease, and deciding on the aetiology of the arthropathy.  Rheumatoid factor (RF) and antibodies to citrullinated peptide (ACPA) have been detected in patients with RA years before the onset of symptoms- evidence that the disease process begins in the preclinical phase, before the onset of symptoms. This study presents a case of aggressive rheumatoid arthritis of wrist joints misdiagnosed as infectious arthritis, which has led to the total joint destruction within a period of 3 years. The patient, a 57-year-old female, presented with complaints of severe pain, swelling and functional disorders of the left wrist joint at the beginning of 2013. She started complaining in December 2010 during the flu infection, accompanied by conjunctivitis. The flu lasted for a month and resulted in severe complications. Rheumatoid factor (RF) and antibodies to citrullinated peptide (ACPA) have been detected in patients with RA years before the onset of symptoms- evidence that the disease process begins in the preclinical phase, before the onset of symptoms. In this case, it was noticed in the lab tests that the ACPA antibodies were serologically positive for RF. According to the ACR 2010 criteria, the consultant in rheumatology affirmed the preliminary diagnosis of rheumatoid arthritis. Unfortunately, the delay in confirming the diagnosis and the destruction of the left wrist led to arthrodesis.

 

Author (s) Details

 

Evija S
Department of Rheumatology, Riga Stradins University, Riga, Latvia.

 

Helena M
Department of Rheumatology, Riga Stradins University, Riga, Latvia.

 

Janis A
Hospital of Traumatology and Orthopedics, Riga, Latvia.

 

Dace V
Hospital of Traumatology and Orthopedics, Riga, Latvia.

 

Please see the book here:- https://doi.org/10.9734/bpi/msraa/v3/5397

Pre-Articular and Explosive form of Rheumetoid Arthritis in a Mongel Dog | Chapter 10 | Innovations in Biological Science Vol. 4

A case of an active-explosive form of Rheumatoid arthritis with poly-arthritis was presented in a mongrel male dog. The same was brought six months back with a pre-articular/ subclinical form with predominate signs of anemia but no lameness. On the basis of its past and present history, clinical examination and hematology, it was diagnosed as a case of flare of active and explosive form of Rheumatoid arthritis. Its etiology, pathology, management and treatment with DMARDs and corticosteroids were discussed.

Author(s) Details:

Arvind Sharma,
Animal Husbandry, Gurdaspur, Punjab, India.

Kiran Preet Kaur
Veterinary Polyclinic, Gurdaspur, Punjab, India.

Sham Singh
Animal Husbandry, Gurdaspur, Punjab, India.

Please see the link here: https://stm.bookpi.org/IBS-V4/article/view/14454

A Comparative Study of Different Types of Joint Effusions in a Tertiary Care Hospital of Northern India | Chapter 12 | Recent Developments in Medicine and Medical Research Vol. 11

 Arthritis is the most common symptom of a variety of joint problems. This is when synovial fluid analysis comes in handy. Synovial fluid analysis has long been advised as a standard procedure for aiding in the diagnosis of arthritis. Synovial fluid moisturises and lubricates the joints by filling the gaps in the joint cavities.

Objective: To improve diagnosis accuracy, examine the gross, microscopic, and biochemical differences in synovial fluid in diverse sources of joint effusions, as well as assess synovial fluid cytology with biochemical parameters in various forms of arthritis.

Materials and Procedures: The synovial fluid of 477 patients was examined in the Department of Biochemistry at SKIMS Medical College & Hospital, Bemina, Srinagar, India, in collaboration with the Department of Pathology. The synovial fluid was separated into two halves after a gross examination to determine its total volume, clarity, and viscosity. The synovial fluid was split in half and sent for biochemical analysis and microscopic examination.

Joint involvement was detected in individuals between the ages of 16 and 75, with 182 males and 295 females among the 477 synovial fluid samples examined.

Septic arthritis had the greatest total leucocyte count, while osteoarthritis had the lowest. Septic arthritis (95 percent) had the most neutrophils, while osteoarthritis had the least (24 percent ). Osteoarthritis and gouty arthritis had the highest sugar levels in synovial fluid (70-90 mg/dL each), while septic arthritis had the lowest. Protein levels were highest in rheumatoid arthritis (4.1-6.5 gm/dL) and traumatic arthritis (4.2-6.4 gm/dL), and lowest in osteoarthritis (1.2-2.4 gm/dL). The maximum number of positive synovial C-reactive protein cases (130) were discovered in rheumatoid arthritis, with rheumatoid factor positive in 143 instances and negative in 127 cases of osteoarthritis.

Conclusion: Protein and sugar biochemical analysis of synovial fluid aids in the diagnosis of various kinds of arthritis. The presence of RF in synovial fluid aids in the diagnosis of monoarticular arthritis. In rheumatoid arthritis, C-reactive protein levels in synovial fluid were high, and this test, along with others, can be used to diagnose the illness. Synovial fluid analysis will be used more frequently in hospital services, assisting clinicians in early management and providing specific benefits in the diagnosis and follow-up of patients with joint illness.

Author(S) Details

Qazi Najeeb Ahmad
Department of Biochemistry, Govt. Medical College Anantnag (J&K) India.

View Book:- https://stm.bookpi.org/RDMMR-V11/article/view/4654