Inflammatory and Immunological Profile of Chronic Obstructive Pulmonary Disease. Basic Research and Clinical Application | Book Publisher International

 This book is built on the assumption that present and future scientific knowledge is and will be predominantly based on understanding of the immunology and inflammation of chronic obstructive pulmonary disease (COPD). Pathophysiology and its clinical, functional, and radiological implications, as well as existing and prospective treatments, all point to a better understanding of the entity's molecular biology. As a result, the book is divided into four distinct portions. Immune recognition, inflammation, immunology, mitochondrial dysfunction, and the rheological features of bronchial mucus are all covered in the first four chapters. That is, the foundations of COPD's immunological and inflammatory characteristics. The second section addresses COPD caused by etiologies other than smoking, which is a subset of COPD that is "on the rise." The treatment of COPD is covered in the third segment, while the fourth portion contains two mandatory chapters on the subject: differential diagnosis and similarities with bronchial asthma, and the influence of COVID-19 on COPD and bronchial asthma.

The major goal is to provide the reader with up-to-date, comprehensive, and concise information on these molecular profiles, which are sometimes difficult to comprehend, by combining multiple chapters into one "whole," as if they were different surfaces of a prism.

We'll be happy if the book gives medical students, physicians, and researchers a better understanding of COPD.

Carmen, Mara, Nico, Jojo, and Pedro are honoured.


Author(s) Details

Alcibey Alvarado González
Clínica de Diagnóstico Médico, Torre Médica, 3er Piso, Paseo Colón, San José, Costa Rica.

View Book:- https://stm.bookpi.org/IIPCOPDBRCA/issue/view/548

A Prospective Study on Evaluation of Salivary Gland Tumors: An Approach to Clinical Radiology and Pathology | Chapter 15 | Highlights on Medicine and Medical Science Vol. 10

 Due to their overlapping appearances, salivary gland cancers are difficult to identify based purely on clinical presentation or cytological results. Inadequate cytology samples can make preoperative diagnosis difficult. The gold standard for diagnosing these malignancies is histopathology. The goal of this study was to determine the clinical, radiological, and cytological features of these tumours and compare them to histopathological diagnosis accuracy. Between 2007 and 2009, 52 patients with salivary gland swellings were enrolled in a prospective study. The study did not include those with inflammatory edoema. Data on demographics, clinical history, ultrasonography, cytology, and histopathology were gathered and analysed prior to surgery. The parotid gland was involved in the majority of cases (65.38 percent). The most frequent benign tumour was pleomorphic adenoma, which accounted for 80.76 percent of all benign tumours. Malignant tumours made up 19.23% of the total. Malignant tumours such as mucoepidermoid carcinoma and adenoid cystic carcinoma were frequent. The most common clinical manifestation was local edoema, with no facial nerve involvement described. The hard palate was the most commonly afflicted minor salivary gland by benign tumours. Fine-needle aspiration cytology had the highest diagnosis accuracy of 96.15 percent, followed by clinical and other tests. 92.31 percent and 86.54 percent radiological diagnosis accuracy, respectively. A significant agreement was found between clinical and histological diagnosis (p=0.1336) and FNAC and histological diagnosis (p=0.4975) using McNemar's test. Fine needle aspiration cytology is a highly precise, sensitive, and specific screening method. Although minimally invasive, it is safe and reliable. Ultrasonography-guided cytology, in combination with clinical and radiographic data, could improve the accuracy of pre-operative diagnosis of salivary gland cancers.

Author (S) Details

Dr. Namita Mishra
Department of ENT, Jawaharlal Nehru Hospital and Research Center, Bhilai, Chhattisgarh, India.

Dr. Neeta Sharma
Department of ENT, Jawaharlal Nehru Hospital and Research Center, Bhilai, Chhattisgarh, India.

View Book :- https://stm.bookpi.org/HMMS-V10/article/view/2263