Assessment of the Changes in the Salivary Profile and its Clinical Correlation in Leukemic Children Undergoing Chemotherapy | Chapter 2 | Disease and Health Research: New Insights Vol. 4

The present study aimed to assess the changes in salivary profile and its clinical correlation in leukemic (ALL) children undergoing chemotherapy. Chemotherapy adversely affects the salivary glands, altering the quality and quantity of saliva. Several chemotherapeutic agents cause damage to the mucosa which affects the dividing cells of Basal epithelium and also, direct contact of these agents with connective tissues can lead to their extensive damage.

 

Children who have been diagnosed with Acute Lymphoblastic Leukaemia undergoing chemotherapy in Bharati Hospital, Pune were included in the study. Those children were included who fulfilled the following inclusion and exclusion criteria. Stimulated salivary samples were collected in sterile vials at 1-, 3-, and 6-month intervals and were assessed for salivary pH and buffering capacity. Caries and oral manifestations were also checked at each interval.  A total of 25 children with ALL undergoing chemotherapy were included to participate in the study. The results were analysed using Statistical Package for the Social Sciences software. All the major changes were seen in the 1st month, that is, the induction phase of chemotherapy. Hence, we can say this is the most affected phase of chemotherapy. Mucositis was more common in the prepubertal age group than the younger age group in the present study. Also, it was more common in girls than boys. Given that parents and kids should be motivated to practice good dental hygiene, this study has clinical significance. To prevent difficulties later on, all preventive dental procedures should be completed as soon as feasible before starting chemotherapy.

 

Author (s) Details

Madhura N Paranjap
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.

 

Preetam Shah
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.

 

Smita Patil
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.

 

Rohan Shah
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India

 

Smita Patil
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.

                                                                                                                                   

 

Laxmi Lakade
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrni/v4/1667

 

Oral Manifestations of Systemic Diseases in Children | Book Publisher International

The oral cavity acts as a window into overall health, often revealing early or significant manifestations of systemic diseases. Oral Manifestations of Systemic Diseases in Children is an essential guide for dental and medical professionals, bridging the gap between the two fields to improve early diagnosis, comprehensive care, and interdisciplinary collaboration.

This book delves into a broad spectrum of systemic conditions affecting children, exploring their oral signs, symptoms and their implications on overall health. It provides valuable guidance on identifying oral manifestations as key diagnostic indicators, including key indicators of conditions like endocrine disorders, hematological diseases, gastrointestinal issues, immunodeficiencies, and genetic syndromes. Detailed discussions include pediatric-specific treatment protocols, management strategies, and antibiotic regimens tailored for systemic illnesses with oral implications.

Supported by case studies, clinical photographs, and up-to-date research, this work underscores the critical role of interdisciplinary collaboration in ensuring comprehensive care for children with complex medical needs. By fostering a deeper understanding of the oral-systemic connection, the book aims to enhance early diagnosis and improve treatment outcomes in pediatric healthcare.

 

An invaluable resource for pediatric dentists, general dentists, pediatricians, and other healthcare professionals, this book bridges the gap between dentistry and medicine, promoting an integrated approach to pediatric patient care.

 

Author (s) Details

Dr. Deepanshi Sharma
Department of Pediatric and Preventive Dentistry, Army College of Dental Sciences, Jai Jawahar Nagar Post, CRPF Road, Secunderabad, Telangana, India.

 

Dr. Krishnapriya Vellore
Department of Pediatric and Preventive Dentistry, Army College of Dental Sciences, Jai Jawahar Nagar Post, CRPF Road, Secunderabad, Telangana, India.

 

Dr. Mayuri Ganesh
Department of Pediatric and Preventive Dentistry, Army College of Dental Sciences, Jai Jawahar Nagar Post, CRPF Road, Secunderabad, Telangana, India.

 

Dr. K Sai Geeta
Department of Pediatric and Preventive Dentistry, Army College of Dental Sciences, Jai Jawahar Nagar Post, CRPF Road, Secunderabad, Telangana, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-81-982889-5-0

Oral Manifestations | Chapter 11 | Clinical Manifestations of Covid-19: A Multi-Disciplinary Approach

 

COVID-19 infection is a threat to the global healthcare system due to its high mortality profile, especially among persons with existing comorbidities. Though the commonest symptoms are fever, cough, sore throat, myalgia, arthralgia, headache, dyspnea, and sputum production, there are variable orofacial manifestations ranging from the more common features (dysgeusia, xerostomia, and oral mucosal lesions) to the less common manifestations (facial paralysis, trigeminal neuralgia, macroglossia, pain and swelling of the masticatory muscles). The tongue is the most common intraoral site affected followed by labial mucosa and palate.

Maintaining a good oral hygiene practice has been associated with a reduction in the severity of COVID-19 symptoms and the treatment for the orofacial manifestations includes the use of topical or systemic corticosteroids, diphenhydramine. Additionally, the use of mouthwash, antibiotics and sometimes no treatment at all, in which case the lesions resolve within 3 to 21 days, can also be explored.

 

Author(s) Details:

 

Adeyemi, Tope Emmanuel
Department of Child Dental Health, Bayero University, Kano/Aminu Kano Teaching Hospital, Kano, Nigeria.

 

Afeez Abolarinwa Salami
Department of Oral and Maxillofacial Surgery, University College Hospital, Ibadan, Nigeria and Faculty of Dentistry, University of Puthisastra, Phnom Penh, Cambodia.

 

Kehinde Kazeem Kanmodi
Faculty of Dentistry, University of Puthisastra, Phnom Penh, Cambodia.

 

Please see the book here:  https://doi.org/10.9734/bpi/mono/978-81-973195-5-6/CH11

Study on Orofacial Manifestations of COVID-19 | Chapter 04 | Issues and Developments in Medicine and Medical Research Vol. 7

 The oral cavity is the human body's entranceway, as well as a key indicator of our overall health. Oral symptoms such as dysgeusia, ulceration, and xerostomia have been observed in this COVID-19 pandemic and are strong predictors of this viral disease. These are reliable clinical indications of the disease's early clinical beginning. The oral features of this novel disease are described in this brief overview.

Author(S) Details

Hariharan Ramakrishnan
Ragas Dental College & Hospital, The TN Dr. MGR Medical University, Tamil Nadu, India.

Maniamuthu Ragupathi
Ragas Dental College & Hospital, Tamil Nadu, India.

View Book:- https://stm.bookpi.org/IDMMR-V7/article/view/5759