The Proportion of Adolescent and Childhood Ovarian Tumors: A Study in Tertiary Care Centre | Chapter 10 | Advanced Concepts in Medicine and Medical Research Vol. 1

 The aim of the study was to shed light on the mathematical differences of ovarian cancers in adolescents and adolescents and to generate exact therapy guidelines. At the level of the organs system, ovarian abnormal growth in animate being is the most frequent cause of morbidity and humanness. In the specialized literature, the place of an inflammatory process is permitted from the early stages of the evolution concerning this pathology.It was a descriptive long-term study on 50 cases of adolescent girls and youth undertaken in the Department of Obstetrics and Gynaecology from February 2018 to July 2019. After proper disease, surgery was performed fully cases and depending upon histopathology and study of animal, adjuvant chemotherapy was likely in selected cases. Patients were followed up weekly till 6 months after discharge. The most average symptom was found expected abdominal pain (42%), most common sign intestinal mass (38%). Out of 50 cases, 12% were raise to be malignant, all of beginning cell origin. Epithelial tumors were erect to be ultimate common ovarian tumors (52%) up to 20 age of age, out of that benign tumors had 48% epithelial inception. However, up to 10 years adult, germ cell tumors were establish to be ultimate common (75%). Only 1 malignant case passed away, belonging to mixed beginning cell sort of advanced stage. Ovarian neoplasm is very troublesome to treat, especially in children and teenagers because fertility protection is required. The cornerstones of treatment contain early detection, ideal therapy, severe follow-up, and emotional support for patients and family.

Author(s) Details:

Bijoya Mukherjee,
Department of Obstetrics and Gynecology, VMMC and Safdarjung Hospital, New Delhi, India.

Anindya Kumar Das,
Department of Obstetrics and Gynecology, Bankura Sammilani Medical College, Bankura, West Bengal, India.

Please see the link here: https://stm.bookpi.org/ACMMR-V1/article/view/12307

Impact of Periodontal Disease on Overall Health | Chapter 1 | Research Developments in Medicine and Medical Science Vol. 10

 Periodontitis is a never-ending inflammatory condition caused by a assorted microbial infection. It is the consequence of complicated interactions 'tween bacteria and susceptible hosts.  The release of supporting-inflammatory cytokines leads to a inferior systemic inflammation that has an effect on the integral status of the patient. Periodontitis has happened associated with several intrinsic conditions like cardiovascular diseases, diabetes, unfavorable pregnancy effects and respiratory infections. In current years, the relationship of periodontitis and fundamental health has existed explored by numerous analysts and it has expanded the skylines of periodontal medicine. This chapter focuses on the effect of periodontitis on unproductiveness, red blood cell parameters, incessant kidney affliction, cancer and mortality. Substantial research displays that oral health is an main component of general well-being, and individuals with periodontitis can be at risk for different diseases as well.

Author(s) Details:

Prashanth Balakesavan,
Department of Periodontology and Oral Implantology, Dr. D.Y. Patil Dental College and Hospital, Maharashtra, India.

Sneha R. Gokhale,
Periodontology and Implantology, M.A. Rangoonwala College of Dental Sciences and Research Centre, Pune, Maharashtra, India.

Vijay Deshmukh,
Department of Periodontology and Oral Implantology, Dr. D.Y. Patil Dental College and Hospital, Maharashtra, India.

Ray C. Williams,
Periodontology, Dean of Dental Medicine, Stony Brook University and School of Dental Medicine, Stony Brook, NY 11794, USA.

Please see the link here: https://stm.bookpi.org/RDMMS-V10/article/view/10672

A Clinical Series of Rare Gynaecological Malignancies- An Overview| Chapter 4| Current Approaches in Science and Technology Research Vol. 13

 This chapter of the book discusses rare gynaecological cancers. 1) Angiomyofibroblastoma (AMF) is a rare, benign soft-tissue tumour that primarily affects the vulvovaginal region of middle-aged women. In the clinic, it's crucial to identify an AMF from other stromal cell lesions. The example of a 35-year-old woman diagnosed with an uncommon, massive pelvic AMF with a benign clinical history is presented. 2)Pediatric ovarian adenocarcinoma; Adenocarcinomas (surface epithelial stromal tumours) account for 80 percent to 90 percent of adult ovarian neoplasms, but only 7% of paediatric ovarian neoplasms. cancerous tumours in children Here is an instance of ovarian adenocarcinoma in a 14-year-old female. 3) A case of uterine PECOMA in a 45-year-old lady is presented. PECOMA (Perivascular epitheloid cell tumour) is a rare mesenchymal tumour.

Author (S) Details

Dr.Veenu Agrawal
Department of Radiotherapy, Government Medical College and Cancer Hospital, Aurangabad, Maharashtra, India.


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The Lifespan Hormesis Phenomenon in a Population does not Make It's Healthier | Chapter 9 | Challenges in Disease and Health Research Vol. 5

Radiation hormesis, when total-body irradiation (TBI) is administered at a cumulative dose of 1.5 Gy at around 0.1 Gy/day, has recently been considered a type of useful cancer therapy. Many studies have linked hormesis to immune system potentiation. The aim of this research was to examine the impact of natural variation on the signs of hormesis in the regenerative state of dog tissues, which are visible across the life span following complete body exposure to low daily doses of external gamma radiation. Ninety beagle dogs of both sexes, from 1 year after birth to death, were irradiated with cobalt 60 at 0.003 Gy/day. Control (n = 169) and irradiated animals underwent clinical examination and autopsy during their entire life and were then retrospectively divided into two subgroups with (W) or without benign tumors or tumors of unknown nature (WO) that were clinically reported throughout the entire lifespan on a single day. Radiation hormesis was observed only in subgroup WO, which in the absence of radiation had a life span (LS) of 10.7 years. In the WO subgroup (p<0.05), the radiogenic prolongation of life to 11.8 years was close to that in the W control and irradiated W subgroups (11.8 and 11.5 years, respectively). The number of solid malignancies found in the control WO subgroup upon autopsy was smaller (39.5%) than that evident in the control W subgroup (60 percent ). The irradiation of the WO subgroup was followed by a small increase (1.14-fold) in the amount of solid malignancies visible during autopsy and in the clinical signs of tissue atrophy and body weight loss (2.4-fold and 2.4-fold respectively) relative to the irradiated W subgroup, but was accompanied by a sharp decrease in the degree of anemia and hematoblastosis (>10-fold for both). The data exclude the notion that radiation is associated with recovery, but suggest that only in poorer animals can such pathologies (e.g., hematoblastosis) be replaced with other less severe somatic diseases. It implies that, at least in mammals, the notion of radiobiological "stimulation" is unacceptable.

Author(s) Details

Aleksey N. Shoutko
Laboratory for Improvement of the Radiation Treatment Methods, Granov’ Russian Research Center for Radiology and Surgical Technologies, 197758, 70, Leningradskaya str., Pesochny, St. Petersburg, Russia.

Ludmila P. Ekimova
Laboratory for Improvement of the Radiation Treatment Methods, Granov’ Russian Research Center for Radiology and Surgical Technologies, 197758, 70, Leningradskaya str., Pesochny, St. Petersburg, Russia.

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