Assessment of Fatty Acids Profile and Oxidative Stability of Eggs from Laying Hens Fed Diets Containing Hemp Seed or Hempseed Cake | Chapter 2 | Newest Updates in Agriculture and Veterinary Science Vol. 3

 

This chapter aims to assess the effects of dietary intake of hemp (seeds or cake) on the fatty acid (FA) profile and oxidative stability of eggs. The increased production of hemp and the availability of hemp seed and hempseed products have created opportunities for use in livestock rations.  One hundred and twenty, 24-week-old Tetra-SL LL laying hens were assigned to three dietary treatments with five replicates of eight hens each (40 laying hens/treatment), in a completely randomized design. The study found that the amount and type of PUFAs, the amount of α-tocopherol, and the duration of egg storage all had a significant impact on the oxidative stability of eggs. The results indicate that hemp seed appears to be more effective than hempseed cake in maintaining the oxidative stability of egg lipids.

Author(s) Details:

D. Mierlita,
Department of Animal Nutrition, University of Oradea, 1 University St., 410087 Oradea, Romania and Doctoral School of Agricultural Engineering Sciences, University of Agricultural Sciences and Veterinary Medicine, 3-5 Manastur St., 400372 Cluj-Napoca, Romania.

Please see the link here: https://stm.bookpi.org/NUAVS-V3/article/view/9666

Liver Damage due to the Interaction of Malathion with Cimetidine in Rat: Advanced Study | Chapter 6 | Technological Innovation in Pharmaceutical Research Vol. 5

 Cimetidine (C) and cimetidine with malathion (M + C) were employed in this chapter to analyze oxidative stress enzymes indicative of liver damage in rats exposed to malathion (M) in a subchronic form. Cimetidine, a histamine H2-receptor antagonist, has been shown to inhibit a variety of CYP450 isoforms. Malathion, an organophosphorus pesticide that is widely used, causes oxidative liver damage. Male Wistar rats weighing 200-250 g were investigated after being exposed to Malathion (0.15 mg/kg/day, 2 mg/kg/day, 15 mg/kg/day) and cimetidine (10 mg/kg/day) were given orally for three weeks. Malathion influences oxidative stress susceptibility and may modify antioxidant defense capacity directly or indirectly. This research will lead to new clinical diagnoses and treatments for pesticide-induced liver disease, as well as a focus on oxidative stress in organophosphate-exposed individuals and the development of intervention approaches.

Aiuthor (s) Details

Alba D. Campaña-Salcido,
Faculty of Medicine, Department of Pharmacology and Toxicology, Autonomous University of Sinaloa, México. A. Obregon Av.and J.O.de Domínguez St., Postal code 80001; Culiacán Sin., México.

Dr. Álvarez A. Anthon,
Faculty of Medicine, Department of Pharmacology and Toxicology, Autonomous University of Sinaloa, México. A. Obregon Av.and J.O.de Domínguez St., Postal code 80001; Culiacán Sin., México.

View Book : https://stm.bookpi.org/TIPR-V5/article/view/1243

Diabetic Retinopathy: Role of Oxidative Stress and Antioxidant Defence System | Chapter 12 | Research Trends and Challenges in Medical Science Vol. 7

 Objectives: To estimate the oxidant/antioxidant status in type 2 diabetic patients with retinopathy and to compare the development of retinopathy with a number of independent variables (age, gender, education, body mass index, diabetes length, glycosylated haemoglobin, hypertension). Design of Analysis: Case-control study. Location and length of the study: Research laboratories, Department of Medical Laboratories, Qassim University College of Applied Medical Sciences, April 2010-April 2011. Methodology: One hundred diabetic patients with retinopathy were included in the study, recruited from King Fahad Specialist Hospital- Buraidah. The control groups were: control group 1 consisted of sixty non-retinopathic type 2 diabetic patients recruited from the Diabetes and Endocrinology Center, KFSH, Buraidah, KSA; and control group 2 consisted of sixty publicly recruited stable 'non-diabetic subjects,' i.e. Estarahes, Estarahes (party lounges). Every subject's blood was used to prepare plasma, serum, and erythrocyte lysate. Using commercial kits supplied by Northwest, U.S.A., human serum 8-OHdG, plasma MDA, and erythrocyte lysate Cu-Zn SOD were estimated. Data was analysed using SPSS software and Win Episcope software. P-values <0.05 were considered to be important. Results: The development of retinopathy was consistently correlated with age, education, period of diabetes, impaired glycaemic control and hypertension (OR 5.891, 4.44, 10.420, 1.699, 1.820 respectively). In addition, increased plasma MDA, elevated serum 8-OHdG levels, and decreased activity of Cu-Zn SOD were observed in diabetic patients with retinopathy relative to control group subjects. Furthermore, in all subjects, negative associations between plasma MDA and Cu-Zn SOD activity, HbA1c & Cu-Zn SOD activity were identified. Conclusion: This research highlights the important role of oxidative stress in the development of retinopathy in type 2 diabetes, indicating that the blocking of oxidative stress is a key step in slowing the progression of diabetic retinopathy, and hence the need to delay the severity of diabetic retinopathy with antioxidant supplements.

Author(s) Details

Abdelmarouf Hassan Mohieldein

Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Saudi Arabia.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/361