Showing posts with label low-density lipoprotein. Show all posts
Showing posts with label low-density lipoprotein. Show all posts

Thursday, 9 February 2023

Effects of Aqueous Fruit Extract of Tamarindus indica on Body Weight, Lipid Profile, Some Electrolytes and Urea of Wistar Rats: Experimental Investigation| Chapter 8 | Current Topics on Chemistry and Biochemistry Vol. 8

 The aim concerning this study search out judge the belongings of liquid extract of T. indica  on the crowd burden, lipid characterization few electrolytes and urea of Wistar rats. The tamarind forest is well used to to a certain extent-dry domains of the torrid zone and can bear dryness environments rather well.  Twenty-five Wistar rats were delivered into four groups involving six rats each. Group I dressed as the control group, while Group II taken 100mg/kg of Aqueous extract, Group III taken 150mg/kg of Aqueous extract, and Group IV taken 200mg/kg of Aqueous extract. The presidency endure seven days, and The Animals were gone on the eighth era. The ancestry was fatigued by way of cardiac puncture and analysed accompanying a seeable spectrophotometer.   The verdicts granted that skilled was no important distinctness (p<0.05) in carcass burden of Wistar rats.  In the Test Groups; Serum cholesterol, reduced mass lipoprotein (LDL), High mass lipoprotein (HDL), Very Low-mass Lipoprotein and Triglycerides accompanied a important increase (p<0.05) distinguished to Group 1 that is the control Group but had a meaningful decrease (p<0.05) distinguished inside test groups. For electrolytes concentrations, potassium, Sodium, Chloride and Urea concentrations was meaningful at p<0.05.  According to the judgments, T. indica extract grant permission help to uphold a active burden, grant permission have hypolipidemic features, grant permission aid in frame equilibrium and fluid balance, and concede possibility likewise assist in preventing renal damage.

Author(s) Details:

I. P. Ekpe,
Department of Biochemistry, Veritas University, Abuja, Nigeria.

Dennis Amaechi,
Department of Biochemistry, Veritas University, Abuja, Nigeria.

B. N. Yisa,
Department of Biochemistry, Veritas University, Abuja, Nigeria.

O. G. Osarhiemen,
Department of Biochemistry, Veritas University, Abuja, Nigeria.

Please see the link here: https://stm.bookpi.org/CTCB-V8/article/view/9425

Monday, 25 April 2022

Reaching LDL-C Goals Using Nudges: A Review of Literatures | Chapter 08 | New Horizons in Medicine and Medical Research Vol. 5

 To analyse the literature and determine how nudges can assist a physician in meeting his or her patients' LDL-C targets. Modifying cardiovascular risk factors can help lower the rate of coronary events in high-risk patients. In the United States and most European countries, coronary heart disease is the leading cause of mortality (CHD). Hypercholesterolemia is the most important risk factor for coronary artery disease. Both high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) are major risk factors for coronary artery disease (CHD). HMG-CoA inhibitors are the most effective medication for lowering LDL-C levels and, as a result, reduce cardiovascular mortality and morbidity. When a decision architecture is built to consistently control behaviour without limiting an individual's choices, it is referred to as a nudge. In order to be effective, the direction and force of a nudge should be compatible with professional standards. The essay discussed how patients' and physicians' actions contributed to the rise in cardiovascular disease prevalence. Nudges, whether digital or manual (using post-its), can persuade doctors to be more proactive and increase patient adherence to therapy. The patient-physician relationship must be built on trust in order to attain these goals. Nudges can be a useful management technique for guiding healthcare providers' right behaviour. The goal is to persuade doctors that they are beneficial rather than obnoxious or domineering.


Author(S) Details

Reagan F. Cabahug
Davao Medical School Foundation, Philippines and Metro Davao Medical and Research Center, Philippines.

View Book:- https://stm.bookpi.org/NHMMR-V5/article/view/6486

Monday, 18 April 2022

Determining the Effect of Curry Leaves and Cucumber Fruit on Lipid Profile in Menopausal Women with Hyperlipidaemia | Chapter 08 | Emerging Trends in Disease and Health Research Vol. 6

 Hyperlipidemia increases the chances of acquiring cardiovascular disease (CVD). Total cholesterol (TC) and triacyl glycerol (TAG) levels in the blood are elevated in hyperlipidaemia. The purpose of this study was to see how curry leaves powder and slicing cucumber fruit affected hyperlipidemia in menopausal women living in rural areas.

Methods: Thirty menopausal healthy women from rural communities (45–65 years old) with mild hyperlipidemia were randomly assigned to one of two groups: control or experimental. The control group received no treatment while the experimental group received cucumber (100-125 g) and curry leaves powder (5 g) once daily for 45 days. A questionnaire was used to collect the demographic information. Fasting blood samples were taken before and after the intervention to assess total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and triacyl glycerol levels (TAG).

TC, LDL-C, and TAG were significantly (p0.05) reduced in the curry leaves powder and cucumber treatment groups. Only the curry leaves powder treatment group had a significantly (p0.05) higher HDL-C level (46.19.2 mg/dl) (average 12 percent). Although the control group's TC, LDL-C, and TAG mean levels were higher, the difference was not statistically significant. When the efficacy of the test chemicals at the tested doses was compared, the HDL-C level in the curry leaves treated group was statistically higher (p =0.09).

Conclusions: In menopausal women with hyperlipidemia, curry leaves and cucumber were successful in boosting HDL-C and decreasing LDL-C and TAG levels, indicating a possible neutraceutical role in CVD treatment.

Author(S) Details


John Molly
Department of Research, Saveetha University, Chennai-603 105, Tamil Nadu, India and Department of Community Health, Amala College of Nursing, Amala Nagar, Thrissur- 680 555, Kerala, India.

Silvia Edison
Department of Medical and Surgical Nursing, Al Shifa College of Nursing, Angadippuram, Malappuram- 679 321, Kerala, India.

R. Vijayaraghavan
Department of Research, Saveetha University, Chennai-603 105, Tamil Nadu, India.

Thekuttuparambil Ananthanarayanan Ajith
Department of Biochemistry, Amala College of Nursing, Amala Nagar, Thrissur- 680 555, Kerala, India.

View Book:- https://stm.bookpi.org/ETDHR-V6/article/view/6420