Showing posts with label immune tolerance. Show all posts
Showing posts with label immune tolerance. Show all posts

Thursday, 15 January 2026

Reproductive and Pregnancy Dynamics in Pigs: Physiology, Biochemistry, Endocrinology and Immunity | Chapter 9 | New Horizons of Science, Technology and Culture Vol. 6

 

Reproduction and pregnancy in pigs involve complex coordination of body temperature, metabolism, hormones, and immune tolerance. Understanding these changes is crucial for reproductive efficiency, maternal health, and fetal survival. This chapter summarises variations in key physiological parameters (rectal temperature, respiratory and pulse rates) across reproductive stages, outlines serum biochemical shifts during gestation, and highlights the roles of hormones like progesterone and oestrogen in supporting pregnancy. It also discusses the immunological environment, shaped by cytokines such as IL-10, IFN-γ, and IFN-β, which maintain uterine immune balance and allow fetal development. These interlinked systems work together to ensure reproductive success. The establishment of pregnancy is further secured by maternal recognition of pregnancy (MRP), involving the integrated actions of reproductive hormones and immune mediators that maintain corpus luteum function and promote a favourable uterine environment.

 

 

Author(s) Details

Rajashree Dutta Purkayastha
College of Veterinary Science, Assam Veterinary and Fishery University, Khanapara, Guwahati-781022, India.

 

Simson Soren
Lakhimpur College of Veterinary Science, Assam Veterinary and Fishery University, Joyhing, North Lakhimpur-787051, India.

 

Sanjib Borah
Lakhimpur College of Veterinary Science, Assam Veterinary and Fishery University, Joyhing, North Lakhimpur-787051, India.

 

Biju Borah
Lakhimpur College of Veterinary Science, Assam Veterinary and Fishery University, Joyhing, North Lakhimpur-787051, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/nhstc/v6/6858

 

Reproductive and Pregnancy Dynamics in Pigs: Physiology, Biochemistry, Endocrinology and Immunity | Chapter 9 | New Horizons of Science, Technology and Culture Vol. 6

 

Reproduction and pregnancy in pigs involve complex coordination of body temperature, metabolism, hormones, and immune tolerance. Understanding these changes is crucial for reproductive efficiency, maternal health, and fetal survival. This chapter summarises variations in key physiological parameters (rectal temperature, respiratory and pulse rates) across reproductive stages, outlines serum biochemical shifts during gestation, and highlights the roles of hormones like progesterone and oestrogen in supporting pregnancy. It also discusses the immunological environment, shaped by cytokines such as IL-10, IFN-γ, and IFN-β, which maintain uterine immune balance and allow fetal development. These interlinked systems work together to ensure reproductive success. The establishment of pregnancy is further secured by maternal recognition of pregnancy (MRP), involving the integrated actions of reproductive hormones and immune mediators that maintain corpus luteum function and promote a favourable uterine environment.

 

 

Author(s) Details

Rajashree Dutta Purkayastha
College of Veterinary Science, Assam Veterinary and Fishery University, Khanapara, Guwahati-781022, India.

 

Simson Soren
Lakhimpur College of Veterinary Science, Assam Veterinary and Fishery University, Joyhing, North Lakhimpur-787051, India.

 

Sanjib Borah
Lakhimpur College of Veterinary Science, Assam Veterinary and Fishery University, Joyhing, North Lakhimpur-787051, India.

 

Biju Borah
Lakhimpur College of Veterinary Science, Assam Veterinary and Fishery University, Joyhing, North Lakhimpur-787051, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/nhstc/v6/6858

 

Saturday, 8 October 2022

Virus-mediated Autoimmunity, Immune Tolerance and Biologic Treatment | Chapter 3 | Research Aspects in Biological Science Vol. 9

 The autoimmune disease process can occur in a variety of chronic human disorders. As a group of diseases, autoimmune disorders are the third most frequent cause of sickness and death in the Western World. The majority of autoimmune illnesses' underlying mechanisms are still unclear. The most significant contributor to the emergence of autoimmune illnesses, above genetic factors and cytokine activity, is viral infection. There are a number of hypothesised mechanisms by which viral infection could impair self-tolerance and set off an autoimmune cascade, ultimately leading to the destruction of a particular type of cell or an entire body organ. The many immune systems and additional potential processes, such as molecular mimicry, bystander activation, and epitope dissemination, can be used to understand the autoimmune onslaught. In addition to genetic and viral factors, other environmental factors such as bacterial, parasitic, and fungal infections are also involved. However, a number of animal models have been examined and offer convincing proof that viruses contributed to AIDs as well as hastened and bigger lesions in environments where self-tolerance was compromised. In this review, we examined virus-induced autoimmunity and the underlying molecular mechanism. We also discussed the several viruses, such as the rubella virus, enteroviruses, measles virus, human T-lymphotropic virus type 1, human cytomegalovirus, human herpes virus-6, Epstein-Barr virus, rotavirus, and others, that influence the development of AIDs as well as its biologic therapy.


Author(s) Details:

Arslan Habib,
Laboratory of Molecular Immunology, School of Life Sciences, Fudan University, Shanghai, China.

Riffat Iqbal,
Department of Zoology, Government College University, Lahore, Pakistan.

Muhammad Usman Taj,
Department of Fisheries and Aquaculture, University of Veterinary and Animal Sciences, Lahore, Pakistan.

Rabia Jahangir,
Department of Zoology, Government College University, Lahore, Pakistan.

Abdul Rehman,
Department of Zoology, Pakistan Institute of Applied and Social Sciences, Kasur, Pakistan.

Ansa Batool,
Department of Zoology, Pakistan Institute of Applied and Social Sciences, Kasur, Pakistan.

Haleema Sadia Jafar,
Department of Zoology, Pakistan Institute of Applied and Social Sciences, Kasur, Pakistan.

Abubakar Muhammad Arshid,
Department of Zoology, Pakistan Institute of Applied and Social Sciences, Kasur, Pakistan.

Shumaila Murtaza,
Department of Zoology, Pakistan Institute of Applied and Social Sciences, Kasur, Pakistan.

Shamim Allah Dita,
Department of Zoology, Pakistan Institute of Applied and Social Sciences, Kasur, Pakistan.                          


Please see the link here: https://stm.bookpi.org/RABS-V9/article/view/8343