Time-Dependent Cox Regression Analysis of Rock Salt | Chapter 7 | Advances and Challenges in Science and Technology Vol. 2

 The main objective concerning this study is to analyse and anticipate the potential risk of rock salt damage using the Cox equivalent hazard model. Analysed according to the belief of continuous mechanism medium rock massif is a natural environment troublesome to know, so the forecasts refer to its behaviour are approximate and changeable. Such an assertion enhances a certitude, even developing from reality; results of the four fundamental features of mountain system are multiple and include really troublesome issues in mining field and mainly, in the constructions field. The concept and the habit to assess the stability of secret construction includes understanding its phenomenological development and doubtless the personality of rocks behaviour in massif. Most of moment of truth, the analysis of the behaviour of the rocks and the chance of their breaking requires concern of the simultaneous belongings of several determinants. Rocks behave otherwise over time, and in any position, there is a feasibility that the break will manifest itself. Many times, we do not have complete information for the study of the resistance period of the rocks. To carry out aforementioned an analysis, we projected the use of a regressive means, that is, the Cox equivalent hazard model. By applying the Cox model or equivalent hazard regression, we have the feasibility of predicting the relative risk (potential risk) of the incident of rock breakage based on various variables. Risk (hazard) can have a different alternative, either in the sense that it can increase in time or possibly decrease; if over time skilled is no variable or determinant that determines an progress towards breaking the rock, then the risk of breaking is lower. Based on the standard scheme of rocks behaviour habit to failure, we are intend a statistical reasoning method of results acquired by laboratory tests using Cox reversion. This method offer the chance to provide quantitatively and qualitatively moment of truth when the breakage happens. The method allows us to establish the link betwixt a certain determinant through which maybe forecasted rock breakage and the talent to resist; the design can be grown and applied massif scale and again in the stability study of underground everything.

Author(s) Details:

Mihaela Toderas,
University of Petrosani, Petrosani-332006, Romania.

Please see the link here: https://stm.bookpi.org/ACST-V2/article/view/11930

Determination of Mining Risks at Exploitation in Roșia Poieni Open Pit Mine, Romania | Chapter 6 | Techniques and Innovation in Engineering Research Vol. 3

 The mining sector is of particular importance as it can support the economic development of the country by supplying various mineral products that are used as raw materials in other fields of activity. When deposit depth and geological conditions permit, valuable mineral resources are mined in open pit mines. The purpose of this document is to investigate malfunctions that may occur and which may lead to dangerous accidents that may affect the safety of personnel and the environment. These malfunctions can be caused by a variety of reasons, including malfunctioning internal mining units and natural phenomena. The study identified and assessed potential mining risks at the Roşia Poieni open pit mine. The policy underlying the identification of these risks considers three main principles. Reduce risk and keep people safe while limiting property risk or financial risk to mining entities. The identification of these risks allows delimiting areas directly or indirectly exposed to potential risks and defines specific prevention, protection and safety measures associated with the activities to be carried out. can do. Based on the identified potential mining risks, we created a hazard map that can be used to develop a risk prevention plan, taking into account the existence of multiple types of risks that may overlap in the same quarry operation area.

Author(s) Details:

Mihaela Toderaș,
Mining Engineering, Surveying and Civil Engineering Department, University of Petrosani, Romania.

Please see the link here: https://stm.bookpi.org/TAIER-V3/article/view/8428

Comparison of Prostaglandin Analogue and Prostaglandin Analogue/Beta-blockers Fixed Combination in Patients with Primary Open Angle Glaucoma | Chapter 03 | New Horizons in Medicine and Medical Research Vol. 2

 The goal of this study was to examine the efficacy and safety of IOP-lowering travoprost 0.004 percent and travoprost 0.004 percent plus beta-blocker 0.5 percent fixed combination ophthalmic solution in patients with open-angle glaucoma and ocular hypertension.

Methods: In this prospective, multicenter clinical trial, 62 patients were administered either travoprost 0.004% (n = 31) or travoprost 0.004% with beta-blocker 0.50% (n = 31). Efficacy and safety were compared among treatment groups over a two-year period. At 3, 6, 12, and 24 months, each group's IOP reduction and adverse events were evaluated.

The mean IOP at the first visit was 26.4 (SD 2.1) in the travoprost 0.004 percent group and 26.3 (SD 2.1) in the travoprost 0.004 percent/timolol 0.5 percent group. After 24 months, the mean IOP in the travoprost 0.004 percent group was 20.5 (SD 1.5), while in the travoprost 0.004 percent/timolol 0.5 percent group was 18.5 (SD 1.5). After the third (after one year) and fourth visits, there were statistically significant differences in IOP in both eyes (after 2 years).

Conclusion: After 2 years of treatment, travoprost 0.004 percent/timolol 0.5 percent provided clinically meaningful IOP reductions in patients with open-angle glaucoma or ocular hypertension that were larger than those achieved by travoprost 0.004 percent alone.

Author(S) Details

Gentian Hoxha
Department of Ophthalmology, Faculty of Medicine, University Clinical Center of Kosovo, Prishtina, Kosovo.

Kelmend Spahiu
Department of Ophthalmology, Faculty of Medicine, University Clinical Center of Kosovo, Prishtina, Kosovo.

Gazmend Kaçaniku
Department of Ophthalmology, Faculty of Medicine, University Clinical Center of Kosovo, Prishtina, Kosovo.

Mimoza Ismaili
Department of Ophthalmology, Faculty of Medicine, University Clinical Center of Kosovo, Prishtina, Kosovo.

Fëllanza Ismajli-Hoxha
Department of Dermatovenerology, Faculty of Medicine, University Clinical Center of Kosovo, Prishtina, Kosovo.

View Book:- https://stm.bookpi.org/NHMMR-V2/article/view/6123