Synthesis and Biological Applications of Ferrocenyl Amino Acids, Sugar and Nucleic Acids Derivatives | Chapter 1 | Advancements in Science and Technology: Paving the Way to a Sustainable Future

Ferrocene, known for its aromaticity, relative lipophilicity, and stable redox properties, has been widely explored in functional molecules due to its unique chemical characteristics. Despite being an organometallic compound, ferrocene and some derivatives maintain stability in aqueous and aerobic environments. Its industrial applications span diverse fields such as petroleum, plastics, textiles, metallurgy, and catalysis. Medicinally, ferrocene and its derivatives demonstrate cytotoxic, antitumor, antimalarial, and antianemic properties, making ferrocene-conjugated biomolecules particularly promising. One approach to enhance ferrocene’s water solubility and biocompatibility is through covalent attachment to biomolecules like amino acids, carbohydrates, and nucleic acids. These conjugates exhibit significant structural, electrochemical, and biological properties. This chapter reviews recent advancements in the synthesis of ferrocene-conjugated carbohydrates and amino acids, focusing on methods such as thio-alkylation, click chemistry, and amide linkage formation. Overall, the chemical versatility and bioactivity of ferrocene derivatives highlight their potential for future applications in medicinal and material science.

 

Author (s) Details

Dr. Anija Mol T Philip
Department of Chemistry, Hislop College, Nagpur, Maharashtra, India.

 

Dr. Mayur V Khedkar
Department of Chemistry, Hislop College, Nagpur, Maharashtra, India.

 

Dr. Shoeb R Khan
Department of Chemistry, Hislop College, Nagpur, Maharashtra, India.

 

Dr. Shibin Chacko
Department of Chemistry, Hislop College, Nagpur, Maharashtra, India.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49473-39-3/CH1

Adsorption of CO2 Molecule on the (MgO)9 and (CaO)9 Nanoclusters | Chapter 6 | Progress in Chemical Science Research Vol. 5

 The end of the present study is to address the response of CO2 on MgO and CaO shells to form carbonate( CO32 −). In addition, an trouble is made to characterise the proposed CO2/( MgO) 9 adsorption by calculating its vibration frequence and compare with trial. A posterior study will address the adsorption of SO2 onto( MgO) 9 and( CaO) 9 cluster models. viscosity functional proposition model simulations are used to study the list configurations of CO2 on the( MgO) 9 and( CaO) 9 cluster models. The results show that CO2 adsorbs as monodentate on MgO and CaO sundeck point leads to conformation of face carbonates CO32 −. Borderline differences in the list stabilities between the CO2 patch and face O2 − point were set up to be significantly analogous. The estimated adsorption powers are1.47 eV and1.52 eV at the( MgO) 9 and( CaO) 9 clusters, independently. The similarity in binding powers is bandied in terms of cluster electro- positivity. Adsorbed CO2, to( MgO) 9 face vibration frequentness are calculated and compared to the trial. It's concluded that in the absence of Madelung eventuality, as the case for clusters, the original Lewis dun at the O2- suds spots display analogous strengths irrespective of the different alkaline earth cations.

Author(s) Details:

Fathi Hassan Bawa,
Department of Physics, Faculty of Science, Misurata University, P.O.Box 2880, Misurata, Libya.

Please see the link here: https://stm.bookpi.org/PCSR-V5/article/view/8483