Interaction between the Reticular Nucleus of the Thalamus and Different Brainstem Structures | Chapter 13 | New Visions in Medicine and Medical Science Vol. 7

The reticular nucleus of the thalamus (TRN) has attracted special attention among diencephalic structures, which are specially related to the genesis of the electrical activity of brain. Brain stem formations also appear to be able to change the activity of other parts of the brain. The aim of this investigation was to study the mechanisms of the relationship between TRN, mesencephalic reticular formation (MRF) and nucleus of the solitary tract (NTS). It has been shown, for the first time, that: firstly, TRN and MRF are functionally interrelated and affect each other reciprocally - activation of TRN mainly inhibits the activity of MRF neurons and vice versa; secondly, stimulation of NTS led to the activation of TRN neurons. Moreover, when recording the activity of TRN and MRF neurons with two microelectrodes, it was shown that, upon NTS stimulation, deep inhibition of MRF neurons occurred in parallel with the activation of TRN neurons. Based on our results, it is possible to make some adjustments to the scheme of the relationship between the synchronizing and desynchronizing structures when changing the functional state of the brain and the place of TRN in this activity. Taken together, these findings indicate that the brainstem exerts substantial control over the activity of TRN neurons, possibly to globally modulate the level of arousal for preparing for consciousness.

Author(s) Details:

Z. I. Nanobashvili,
Laboratory of Neurophysiology, I. Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.

I. G. Bilanishvili,
Laboratory of Neurophysiology, I. Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.

B. B. Buachidze,
Ilia State University, Tbilisi, Georgia.

M. D. Barbakadze,
Laboratory of Neurophysiology, I. Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia and Teaching University “GEOMEDI”, Tbilisi, Georgia.

N. A. Khizanishvili,
Laboratory of Neurophysiology, I. Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia.

Please see the link here: https://stm.bookpi.org/NVMMS-V7/article/view/14230

Some Characteristics of Neurons in the Reticular Nucleus of the Thalamus | Chapter 6 | Current Progress in Medicine and Medical Research Vol. 6

 The results concerning this study demonstrate, for the first occasion, that generation of spike potentials of various amplitudes was observed in the venture of the thalamic reticular core neurons. The generation of one operation potential does not interfere accompanying the generation of another, and a pierce potential of smaller size can occur at the ascending or downward phase of the pierce potential of large size. It can be argued that the pierce potentials of lower amplitudes arising in the thalamic troublesome nucleus neuron are of decorated with flowers origin. Given both the calculated position and the functional purpose of the NRT, it maybe assumed that the neurons concerning this structure must each occasion be discharged with pierce potentials in order to complete activity their modulating effect on other fields of the nervous system of the brain outside leakage.

Author(s) Details:

Z. I. Nanobashvili,
Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Neurophysiology, Tbilisi, Georgia.

I. G. Bilanishvili,
Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Neurophysiology, Tbilisi, Georgia.

M. G. Barbakadze,
Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Neurophysiology, Tbilisi, Georgia.

N. A. Khizanishvili,
Ivane Beritashvili Center of Experimental Biomedicine, Laboratory of Neurophysiology, Tbilisi, Georgia.

Please see the link here: https://stm.bookpi.org/CPMMR-V6/article/view/11478