Optimizing Food Container Design: Taguchi Method and S-N Ratio Analysis for Reduced Shrinkage and Warpage | Chapter 8 | Current Approaches in Engineering Research and Technology Vol. 5

 

Plastic materials are commonly used in various industries due to their special properties including corrosion resistance, lightness, and ease of giving shape. In this study, a food container design was analyzed numerically using a combination of various advanced optimization techniques including the Taguchi Method and S-N Ratio Analysis. The main goal is to maximize product efficiency and quality to improve the strength of product outcomes by identifying and minimizing the impact of various sources of variability. The results showed that to reach the optimum performance, the parameters for melt temperature at 200°C, mold temperature at 30°C, filling time at 1.5 s, pressure holding time 5 s, and pure cooling time at 20 s. The optimum result achieved 0.34 mm and 15.95%, for warpage and shrinkage, respectively. The warpage and shrinkage reduction reached 34.6% and 12.1%, respectively, in comparison with the initial design.

 

 

Author(s) Details

Mehdi Moayyedian

College of Engineering and Technology, American University of the Middle East, Kuwait.

Areej Alhuwais

College of Engineering and Technology, American University of the Middle East, Kuwait.

Altaf Almutairi

College of Engineering and Technology, American University of the Middle East, Kuwait.

Dalal Alkandari

College of Engineering and Technology, American University of the Middle East, Kuwait.

Fatma Ali

College of Engineering and Technology, American University of the Middle East, Kuwait.

Fatma Alwazzan

College of Engineering and Technology, American University of the Middle East, Kuwait.

 

Please see the book here:- https://doi.org/10.9734/bpi/caert/v5/958

An Overview of Statistical Techniques for Analysis of Data in Agricultural Research | Chapter 11 | Emerging Issues in Agricultural Sciences Vol. 8

 The significance of statistical analysis is paramount in research, particularly in situations involving the collection, classification, analysis, and interpretation of numerical data. Statistical principles find widespread application in various types of experimental studies and serve as a critical component in agricultural research endeavors. The inherent variability present in commonly used experimental materials within agricultural research necessitates the utilization of statistical methods, leading to numerous advancements and innovations in the field of statistics. The selection of an appropriate tool for data analysis and subsequent processes involving statistical components has become a matter of concern. This chapter delves into the diverse statistical techniques essential for the analysis of agricultural data and the derivation of valid conclusions.

Author(s) Details:

Rahul Banerjee,
ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, Pusa, New Delhi, India.

Bharti,
ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, Pusa, New Delhi, India.

Pankaj Das,
ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, Pusa, New Delhi, India.

Varun Srivastava,
Department of Computer Science and Information Technology, Jaypee Institute of Information Technology, Noida, India.

Ankita,
Department of Agricultural Statistic and Computer Application, Birsa Agricultural University, Kanke, Ranchi, India.

Suraj Kataria,
Department of Anthropology, University of Delhi, Delhi, India.

Bulbul Ahmed,
Department of Agriculture, Galgotias University, Greater Noida, India.

Nitin Varshney,
Department of Agricultural Statistics, Navsari Agricultural University, Navsari, India.

Please see the link here: https://stm.bookpi.org/EIAS-V8/article/view/12877

An Exploration of Hierarchical Interrelationships amongst User Experience Based Experimental Design Challenges in Healthcare Industry | Chapter 6 | Contemporary Perspective on Science, Technology and Research Vol. 6

Following chapter discusses the world wide concept of experimental designs also known as Design of Experiments [DOE] with respect to user experience [UX] and its associated uses and challenges faced by design researchers. Thereafter, the hierarchical inter-relationships amongst them have been created through matrices as per VAXO technique as mentioned in ISM methodology.

Author(s) Details:

V. K. Aggarwal,
Recventures Education Services Private Limited, New Delhi, India.

Remica Aggarwal,
Galgotias University, Greater Noida, U.P, India.

Please see the link here: https://stm.bookpi.org/CPSTR-V6/article/view/13563

Processing and Characterization of Tribological Properties of Al6061-TiB2 Composite by Taguchi Technique | Chapter 4 | Technological Innovation in Engineering Research Vol. 5

In today's engineering design and development operations, composite materials, which are the combination of two or more materials that are distinct from one another in form and chemical composition, are rapidly assuming increasing significance as a structural material. Many academics are working hard right now to create new and innovative materials for a variety of engineering applications employing various AMCs.

In order to explore the tribological behaviour, attempts are undertaken in this research to create Al-6061/TiB2 composites with varied weight percentages of reinforcement via in-situ stir casting. To assess wear loss and coefficient of friction, abrasive wear experiments were carried out using a pin-on-disc (POD) wear test device in accordance with the Design of Experiments (DOE). The wear loss and COF were further optimised using the Taguchi Technique, Analysis of Variance (ANOVA), and Regression studies. To further examine the wear behaviour of the produced composites, scanning electron microscopy (SEM) photographs of worn-out surfaces are employed. With a rise in the weight percent of reinforcement, wear loss and COF decrease. The ANOVA and regression analyses lead to the conclusion that reinforcement is essential to the growth of the Al 6061-TiB2 composite system.

Author (s) Details:

H. S. Manjunatha,
Department of Mechanical Engineering, JSS Science and Technology University, SJCE, Mysuru 570006, Karnataka, India.

V. T. Satish,
Department of Mechanical Engineering, MCE, Hassan, Karnataka, India.

G. Mallesh,
Department of Mechanical Engineering, Sri Jayachamarajendra College of Engineering, Mysuru, Karnataka, India.

S. Ezhil Vannan,
Department of Mechanical Engineering, MCE, Hassan, Karnataka, India.

Please see the link here: https://stm.bookpi.org/TIER-V5/article/view/7463

Determination of Improved Efficacy and Stability of Silymarin Loaded Nanocochleates Over Liposomes for the Treatment of Skin Diseases | Chapter 10 | Current Aspects in Pharmaceutical Research and Development Vol. 6

 Aim: The anti-oxidant, anti-inflammatory, and membrane-stabilizing properties of silymarin, a complex polyphenolic component mixture, are being studied in a variety of dermatological disorders. The goal of this study is to see if silymarin-loaded nanocochleates and liposomal topical treatment can help with chronic skin conditions.

The purpose of this study was to create and assess Silymarin-loaded liposomes, as well as to optimise the process. Conversion of these liposomes into nanocochleates for better drug entrapment, antibacterial activity, cytotoxicity against HaCaT cell lines, and short-term stability investigations.

Design Expert software was used to develop and optimise silymarin-loaded liposomes and nanocochleates. To compare their performance, different invitro and exvivo experiments were used.

Methodology: Liposomes were created by injecting ethanol into them, then trapping them with calcium chloride to form nanocochleates. Nanocochleates were optimised using a design of experiments (32 Factorial Design). To compare efficacy and stability, cell line experiments (HaCaT cell lines) and short-term stability tests were conducted.

Results: Nanocochleates outperformed liposomes in terms of particle size, entrapment efficiency, and drug deposition in Wistar Rat Skin, demonstrating their superiority. Both carriers maintained silymarin release for 24 hours. Nanocochleates had a considerable antimicrobial activity against E.coli and S.aureus. The superiority of nanocochleates over liposomes was established by their ability to inhibit excessive proliferation of HaCaT cell lines (a crucial mechanism by which most antipsoriatic medications work). Nanocochleates also had superior stability than liposomes, owing to lower drug entrapment efficacy and leakage.

Conclusion: Nanocochleates containing silymarin could be an effective topical drug delivery technology for chronic skin conditions such as psoriasis.

Author(S) Details

Rukhsana Rub
Department of Pharmacognosy, STES’s Smt. Kashibai Navale College of Pharmacy, Kondhwa(Bk), Affiliated to Savitribai Phule Pune University,Pune-411048, India.

Neha Munot
Department of Pharmaceutics, STES’s Smt. Kashibai Navale College of Pharmacy, Kondhwa (Bk), Affiliated to Savitribai Phule Pune University, Pune-411048, India.

Akshay Wadate
Department of Pharmaceutics, STES’s Smt. Kashibai Navale College of Pharmacy, Kondhwa (Bk), Affiliated to Savitribai Phule Pune University, Pune-411048, India.

View Book:- https://stm.bookpi.org/CAPRD-V6/article/view/5162

Design of Experiments: A Tool for Statistical Analysis | Chapter 9 | Current Aspects in Pharmaceutical Research and Development Vol. 5

 Quality by Design (QbD) has various advantages in the field of new product development, including less annoyance, increased efficiency, reduced regulatory compliance obligations, and increased customer loyalty. The FDA and the pharmaceutical industry take a more rigorous approach to the creation of medications. Scientific, holistic, and risk-based approaches should be considered when developing new medications. QbD elements are specified when a corporation designs and develops a product. Several input elements influence the quality of procedures and products in general. Using the design of experiment, researchers have recently concentrated on understanding the impact of multidimensional and interrelated input elements on the outputs of medications and analytical methods (DoE). It also looks at how DOE might be applied for both students and teachers, as well as historical viewpoints on DOE. A well-designed experiment can help you make the most of your resources while also making it easy to examine the data. The importance of collaborations between scholars and practitioners in pushing the boundaries of experimental design is investigated. It covers the fundamentals and applications of the most common screening and response surface designs, as well as how to create blended designs.

To put it another way, the goal of the experiment is to reduce ambiguity and uncertainty. Relationships between and among variables are investigated in a good experimental design; in general, one variable, the independent variable, is controlled to quantify its effect on other variables. Any researcher utilising experimental design should be concerned about dependent control; in experiments, the researcher chooses an intervention that is linked to the independent variable and then controls how that intervention is used in the research environment. A causal relationship between the independent and dependent variables can be established if the experimental design is followed correctly.

Author(S) Details

Deep Patel
School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, Paud Road, Kothrud, Pune 411038, India.

Sushant Dangat
School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, Paud Road, Kothrud, Pune 411038, India.

Ashwin Kuchekar
School of Pharmacy, Dr. Vishwanath Karad MIT World Peace University, Paud Road, Kothrud, Pune 411038, India.

View Book:- https://stm.bookpi.org/CAPRD-V5/article/view/4944