Investigating the Anti Alzheimer Activity of Citrus maxima (J. Burm.) Merr Fruit Peel Extract in Mice Using Scopalamine Induced Alzheimer’s Disease| Chapter 2 | Current Overview on Pharmaceutical Science Vol. 3

 Alzheimer's disease is a growing neurodegenerative disease that decays over opportunity and typically influences the elderly, giving reason for 60% of dementia cases in those 65 and earlier.  The current study focuses on thepharmacological project of fruit peels of Citrus maxima (J.Burm.) Merr. in Scopolamine persuaded  Alzheimer’s disease. The Morris labyrinth and Y Maze orders were used to examine concerned with manner of behaving changes in the four groups of mice. Rivastigmine was secondhand as the standard in the investigations. Following the studies, the whole mind was homogenized and allure acetyl cholinesterase content was measured. The results told that the ethanolic extract Citrus maxima peel has anti-alzheimer exercise, accompanying a decrease in brain acetyl cholinesterase levels, and maybe used to treat Alzheimer's disease.

Author(s) Details:

P. Vijayalakshmi,
Department of Pharmaceutical Technology, Adamas University, Barasat, Kolkata, India and Department of Pharmacognosy, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced, Studies, Chennai, Tamil Nadu, India.

R. Radha,
Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai – 600003, India.

Malarkodi Velaraj,
Department of Pharmacognosy, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced, Studies, Chennai, Tamil Nadu, India.

Please see the link here: https://stm.bookpi.org/COPS-V3/article/view/9107

Determination of Photochemical Screening, Antimicrobial and Antioxidant Activity of Citrus Maxima Peel | Chapter 09 | Current Aspects in Pharmaceutical Research and Development Vol. 8

 Citrus maxima (pomelo) was found to have antimicrobial action against many microbe strains, notwithstanding the unfavourable results of this study. Resistance of tested bacterial strains, temperature of preparation conditions, and low concentration of phytochemical present in the plant extract are all factors that can affect their antibacterial efficacy. Malaysia is well-known for growing "Citrus maxima," also known as pomelo. Pomelo is beneficial to the body's immunological system, weight loss prevention, and anti-aging. Pomelo can also help with constipation by promoting digestion and peristalsis. Potassium (an excellent vasodilator) and vitamin C are abundant in pomelo (an antioxidant). With n-hexane, the peel of Citrus maxima was macerated and extracted using the Soxhlet method. Citrus maxima extracts were tested for antimicrobial activity using the "Well Diffusion" method and comparing the clear inhibition zone of a standard antibiotic to the extracts on "Mullen-Hinton agar." Citrus maxima's antioxidant activity was measured using the DPPH radical-scavenging activity of total phenol test. All of the extracts passed the alkaloids qualitative test. Terpenoids were found in the filtrate and residue following maceration, however terpenoids were not found in the Soxhlet sample. Flavonoids were only discovered in the residue. The researchers looked at the total phenolic chemicals in the hexane extract and discovered that the higher the sample concentration, the higher the GAE value.

Author(S) Details

Naeem Hasan Khan
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Malaysia.

Chin Jia Qian
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Malaysia.

Nabila Perveen
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Malaysia.

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