The present study aims to evaluate the effects of the aqueous
extract of Zingiber officinale (Ginger) rhizomes on reproductive parameters in
female Wistar rats. The rhizome of Zingiber officinal (Ginger) is widely
consumed as a juice and spice in the Congo and is also used in the treatment of
various pathologies. Modern Western medicine has ignored most of these
resources by developing chemical drugs and sophisticated treatment techniques
while continuing to use certain plant remedies. Four batches of four female
rats each received the aqueous rhizome extract of Zingiber officinal (Ginger)
at doses of 300 and 600 mg/kg, 17β-estradiol at a dose of 1 mg/kg and distilled
water, orally for 14 aqueous ginger extract non-significantly increased and
decreased rat body weight at 300 and 600 mg/kg respectively. The 600 mg/Kg dose
blocked the sexual cycle at the estrus stage and lowered plasma estradiol
levels. Whereas the 300 mg/kg dose increases plasma estradiol levels with a
more or less regular sexual cycle. Chemical screening of this extract revealed
the presence of flavonoids, tannins, anthraquinones and steroids. It would be
desirable to evaluate sub-acute and chronic toxicity studies of the aqueous
extract of Ginger rhizomes and the effects of this extract on sexual parameters
in male rats. Also, to develop an improved traditional medicine for the
treatment of reproductive disorders.
Author (s)
details:-
Peneme B.
M. L.
Laboratory of Pharmacognosy and Experimental Pathophysiology (L2PE),
Faculty of Sciences and Technology (FST), Marien University, Ngouabi, B.P. 69,
Brazzaville, Congo.
Akassa H.
Laboratory of Pharmacognosy and Experimental Pathophysiology (L2PE),
Faculty of Sciences and Technology (FST), Marien University, Ngouabi, B.P. 69,
Brazzaville, Congo.
Ondélé R.
Laboratory of Pharmacognosy and Experimental Pathophysiology (L2PE),
Faculty of Sciences and Technology (FST), Marien University, Ngouabi, B.P. 69,
Brazzaville, Congo.
Backala
Lanzah A.
Laboratory of Pharmacognosy and Experimental Pathophysiology (L2PE),
Faculty of Sciences and Technology (FST), Marien University, Ngouabi, B.P. 69,
Brazzaville, Congo.
Etou Ossibi
A. W.
Laboratory of Pharmacognosy and Experimental Pathophysiology (L2PE),
Faculty of Sciences and Technology (FST), Marien University, Ngouabi, B.P. 69,
Brazzaville, Congo.
Abena A. A.
Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences
(FSSA), Marien University, Ngouabi, B.P. 69, Brazzaville, Congo.
Please See the book here :- https://doi.org/10.9734/bpi/mria/v1/3750G
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