This article describes the various hyphenated techniques, a
brief note on their instrumentation, and the working principles that are used
in the current setup of industries. The hyphenated technique is the combination
or the coupling of the different analytical techniques. Mainly chromatographic
techniques are combined with spectroscopic techniques. Then the separated
components of the mixture from chromatographic technique will enter into the
spectroscopic technique through an interphase.
Like-wise their remarkable improvement and efficiency over
the past decade. Techniques like single quadrupole inductively coupled mass
spectrometry (ICP-Q-MS), ICP- Triple quadrupole mass spectrometry (ICP-QQQ),
Liquid Chromatography-Two -dimensional Gas chromatography-mass spectrometry
(LC-GCXGC-MS/MS), Two-dimensional liquid chromatography (2D-LC), Fourier
transform near-infrared spectroscopy (FT-NIR), etc. are considered as recent
improvements in this trend. Creating hyphenated methodologies is beneficial to
many scientific domains, such as food and drug analysis and biological
research. Apart from the enhancement, significant dimensional alterations have
been noted in elemental specifications and natural product analysis. Advances in analytical techniques for the
separation and detection of substances have empowered the identification of
compounds in complex mixtures, in addition to making it conceivable to acquire
the metabolic profile of plants, evading the re-isolation of known compounds by
the procedure of dereplication.
Author(s)details:-
Chandan C.
Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS Academy
of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India.
Dhatri T. N.
Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS Academy
of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India.
Jero Victor Wilson
Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS Academy
of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India.
M. R. Jeyaprakash
Department of Pharmaceutical Analysis, JSS College of Pharmacy, JSS Academy
of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India.
Please See the book
here :- https://doi.org/10.9734/bpi/prrat/v2/52
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