Raphia
hookeri gum is an exudate of the Raphia hookeri tree. The tree is common in
humid tropical
rain forest of Africa and Western Asia where the gum
attains its popularity. For its desirable
emulsifying, stabilizing, binding, good flow
properties, sustained-release, rheological, spectroscopic
and physicochemical properties make it suitable as
pharmaceutical excipient. The low protein
contents couple with absence of fibres also confirm the
emulsifying properties of RhG. Its pH sensitive
nature may make it useful in intestinal/colon drug
delivery. Current literature shows the presence of
saponins 2.08 - 3.98 mg / 100 g, alkaloids alkaloids
(0.28-0.49 mg 100g-1), tannins (0.47-0.72 mg
100g-1), flavonoids (0.26-0.39 mg 100g-1), and phenolic compounds (0.01–0.05 mg 100g-1). The
carbohydrates, lipids and protein content were
77.42-78.90%, 2.02-4.185% and 16.63-18.38%
respectively. The exudates are good source of water-
soluble vitamins; ascorbic acid (7.04-26.40 mg
100g-1), niacin (3.12-4.00 mg 100g-1), riboflavin (0.14-0.54 mg 100g-1) and thiamine (0.15-0.22 mg
100g-1),). Its foray into all these properties fuel further investigation into
its unexplored functionality.
The objective of this review was to highlight the
recently unraveled potential of this gum as
pharmaceutical excipient and its future prospects.
Author(s) Details
Stephen Olaribigbe Majekodunmi
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of
Pharmacy, University of Uyo, P.M.B. 1017, Uyo, Akwa-Ibom State, Nigeria.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/222
No comments:
Post a Comment