Ehlers-Danlos syndrome (EDS)
comprises a series of rare hereditary connective tissue diseases
characterized by musculoskeletal, skin and
cardiovascular involvements. EDS may be associated with physical as well as psychological pain that can lead to
psychiatric problems. EDS imposes substantial psychological
burden on patients, and recent large-scale studies have suggested that patients
with EDS have a higher risk of mood disorders
than the general population. To the best of our knowledge, we describe, for the first time, the cases of two Japanese
patients with EDS complicated with mood disorders
who secondarily developed transvestism that was judged strongly related to
early stressful situations through childhood and
adolescence. The first case was of a man in his mid-30s and the second of a woman in her late 20s. We report on detailed
psychosocial data to further discuss the medical
management and genetic counseling of such infrequent but challenging
conditions. Physicians are advised to be aware
of various potential psychological and psychiatric issues that may accompany EDS.
Author
(s) Details
Hiroki Ishiguro
Department of Neuropsychiatry and Clinical Ethics, Graduate School
of Medicine, University of Yamanashi, Japan and Genetic Disease Medical Center,
University of Yamanashi Hospital, Japan..
Naomi Honobe
Department
of Neuropsychiatry and Clinical Ethics, Graduate School of Medicine, University
of Yamanashi, Japan.
Mariko Tamai
Genetic Disease Medical Center, University of Yamanashi Hospital,
Japan and Department of Fundamental Nursing, School of Health Sciences,
University of Shinshu, Japan.
Takaya Nakane
Genetic Disease Medical Center, University of Yamanashi Hospital,
Japan and Department of Pediatrics, Graduate School of Medicine, University of
Yamanashi, Japan.
View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/243
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