Exploring Secondary Metabolites: An Introduction | Chapter 2 | Natural Products Chemistry: From Discovery to Applications, Edition 1

Secondary metabolites are chemical substances that are produced by certain animal systems, microbial systems, and plants. However, the producing organism does not primarily rely on these compounds for growth, development, or interaction with its environment. Unlike primary metabolites, which are involved in the essential biochemical functions of the organism, secondary metabolites are primarily involved in the interaction of an organism with its population. This interaction includes competition, defense, and, potentially, reproduction, through the attraction of pollinators. These products, which exhibit a variety of bioactivities, have been employed in the fields of biotechnology, agriculture, pest control, and drug formulation. They include alkaloids, terpenoids, flavonoids, and phenolics. It is crucial to investigate secondary metabolites in the context of contemporary pharmacotherapy, as numerous compounds exhibit potent properties.

 

Author (s) Details

Keshari Nandan
Department of Chemistry, Gurukul Kangri Vishwaidyalaya, Haridwar-249404, Uttarakhand, India.

 

Deepanshu Rana
Department of Microbiology, School of Lifesciences, Sardar Bhagwan Singh University, Balawala, Dehradun-248161, Uttarakhand, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-48388-70-4/CH2

Plant Secondary Metabolites and Their Therapeutic Properties for Cancer Treatment | Chapter 13 | Socio-Scientific Interaction in Diabetes and Cancer and Its Management

 Plant secondary metabolites have peculiar roles in an organism such as defense, signaling and transport of metals. These secondary metabolites can induce or inhibit various physiological activities and have been used for treatment of multiple diseases including cancer. The bioactive compounds obtained from plant metabolites play an important role in controlling cancer symptoms and treatments, with minimum side effects. Many plant secondary metabolites related to terpenes, phenolics, nitrogenous and sulfur-containing compounds have anticarcinogenic properties and some are commercially available in the market. The objective of this paper is to study various plant secondary metabolites that have ability to kill or inhibit the cancerous cells and their possible mechanisms involved for the inhibition or killing of cancer cells. The plant secondary metabolites act as bioactive molecules to inhibit or suppress various metabolic pathways related to cancer treatment these compounds are biologically friendly and less toxic to the normal cells. The discovery and development of plant metabolite-based drugs provide a futuristic approach to treatment of cancer.

Author(s) Details:

Khirabdhi Tanaya,
Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar-845401, India.

Durgeshwer Singh,
Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar-845401, India.

Please see the link here: https://stm.bookpi.org/SSIDCIM/article/view/12731

Rhodium-phosphite Catalysed Hydroformylation of Camphene and Other Terpenes | Chapter 3 | Current Perspectives on Chemical Sciences Vol. 7

With homogeneous Rh, Co, and Pt metal complexes, the hydroformylation of camphene and other terpenes has been studied. The catalyst system of Rh(CO)2(acac)/P(OPh)3 was found to be very active with almost complete selectivity for aldehyde products. The position of ligands, solvents, Rh:P ratio and conditions of reaction to camphene hydroformylation activity and selectivity have been evaluated. Camphene hydroformylation kinetics were investigated in the presence of the catalyst [Rh(CO)2(acac)]/P(OPh)3 in a temperature range of 363-383K.

Author (s) Details

Dr. Nitin S. Pagar
Homogeneous Catalysis Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India and Post Graduate Department of Chemistry, Sir Parshurambhau College, (Affiliated to Savitribai Phule Pune University), Pune-411030, India.

Dr. Raj M. Deshpande
Homogeneous Catalysis Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India.

View Book :- https://stm.bookpi.org/CPCS-V7/issue/view/5