The Peptide Visualizer and COVID-19 Protein Feature Captivation | Chapter 10 | Research Aspects in Biological Science Vol. 3

The peptide visualizer was created to capture the essential characteristics of coronavirus peptides using RGB colour and geometric forms that differed based on the amino acid type, molecular weight, charge, and polarity. The charts show the sequence and functional characteristics of the peptides in this fashion. It offers a unique perspective on peptide properties in different coronavirus species. The method effectively recognised the S protein RBD region in the four coronavirus subtypes: OC43, HKU1, MERS, and SARS, as shown in the study. The visualizer can detect minor changes in peptide sequences, which might help with coronavirus diagnosis, treatment, and prevention. More than only graphing coronavirus peptides can be done with the application. It may be used to see changes in peptide sequences, structures, and other things. In both prokaryotes and eukaryotes, it plays a role.

Author(s) Details:

Samuel Krem,
Buckingham Browne and Nichols School, Cambridge, MA 02138, United States.

Please see the link here: https://stm.bookpi.org/RABS-V3/article/view/7052

In Silico Prediction and 3D Model Analysis of Potential Epitope of Heat Shock Protein-70 (HSP70) Gallus gallus as Candidate Biomarkers for Poultry Meat Quality Tests| Chapter 8 | Emerging Challenges in Agriculture and Food Science Vol. 5

The major goal of this study was to look for possible heat shock protein-70 (HSP70) epitopes in chickens (Gallus gallus). The epitopes are crucial for developing a vaccination that will generate antibodies against HSP70, which can then be utilised as biomarkers to evaluate HSP70 expression. There is a link between HSP70, which indicates the presence of stresses, and meat quality, according to other studies. Physical, chemical, and biological stresses can reduce the quality of bird meat before, during, and after broiler slaughter. The discovery of a possible biomarker for HSP70 will be extremely useful in determining the quality of poultry meat. In this work, the HSP70 sequences of Gallus gallus were analysed in silico to look for possible epitopes as biomarkers. The approach employed was a bioinformatics-related software-based method. Two putative biomarker candidate peptides related to HSP70, AILMGDKSENVQD and ISWLDRNQMAEKEEYEHKQKELEK, were obtained from this investigation. These epitopes can also be used to create a three-dimensional model. More study is needed to demonstrate the efficacy of these two indicators in vivo.

Author(s) Details:

Sulaiman Ngongu Depamede,
Fakultas Peternakan Universitas Mataram, Jl. Majapahit 62 Mataram, NTB, 83125, Indonesia.

Budi Indarsih,
Fakultas Peternakan Universitas Mataram, Jl. Majapahit 62 Mataram, NTB, 83125, Indonesia.

I Ketut Gede Wiryawan,
Fakultas Peternakan Universitas Mataram, Jl. Majapahit 62 Mataram, NTB, 83125, Indonesia.

Muhamad Hasil Tamsil,
Fakultas Peternakan Universitas Mataram, Jl. Majapahit 62 Mataram, NTB, 83125, Indonesia.

. Maskur,
Fakultas Peternakan Universitas Mataram, Jl. Majapahit 62 Mataram, NTB, 83125, Indonesia.

Please see the link here: https://stm.bookpi.org/ECAFS-V5/article/view/6983