A Brief Case Report on Pregnancy Management and Outcome in Adamts13 Deficiency| Chapter 17 | Issues and Developments in Medicine and Medical Research Vol.11

TTP is a hereditary haematological illness characterised by a deficiency of "Von Willebrand factor cleaving protease" and severe thrombotic microangiopathy, which leads in microangiopathic hemolytic anaemia. The following ailment, which affects people of all ages and has variable degrees of severity, is supported by several records. Patients with inherited TTP have a higher risk of becoming pregnant. In this study, a 25-year-old pregnant lady is examined, her blood parameters are analysed, and treatments are prescribed depending on the findings. According to the indicated outcome, pregnant women had a significantly higher chance of carrying the inherited TTP. All haematological units must be adequately tested throughout pregnancy, and a psychological evaluation is also required.

Author(s) Details:

Lubna Khan,
Department of Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Saudi Arabia.


Maysoon S. Al Adham,
Department of Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Saudi Arabia.

Viquar Qureshi,
Department of Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Saudi Arabia.


Tahira Jamil,
Department of Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Saudi Arabia.

Shoeb Qureshi,
Department of Research, King Saud Bin Abdulaziz University for Health Sciences, National Guards, Saudi Arabia.

Please see the link here: https://stm.bookpi.org/IDMMR-V11/article/view/6089

Determining the Relationship between Platelet Indices and Microvascular Complications in Type 2 Diabetic Patients | Chapter 22 | Recent Developments in Medicine and Medical Research Vol. 6

 Diabetes is a prevalent metabolic illness that affects the entire world's population and causes a large amount of morbidity and mortality, owing to its micro- and macrovascular consequences. The link between platelet indices such as mean platelet volume, platelet distribution width, plateletcrit, and total platelet count in diabetic patients with and without microvascular issues is investigated in this study. Until 2019, this review of the literature was conducted utilising a public access website such as PubMed, Google Scholar, or Medline databases. Patients with macrovascular issues and those using drugs that alter platelet indices were the main exclusion criteria in the investigations. These articles were all scrutinised. Platelet indices such as mean platelet volume and platelet distribution width were significantly higher in those with microvascular complications, especially Diabetic Nephropathy and Diabetic Retinopathy, when compared to those without. Changes in platelet indices were found to be significantly associated to diabetic microvascular issues. As a result, these characteristics can be used to track and predict the risk of microvascular complications.

Author(S) Details

Siva Ranganathan Green
Department of Medicine, Mahatma Gandhi Medical College, Sri Balaji Vidyapeeth University (Deemed to be), Pondicherry, India.

Subashini Subramanian
Department of Medicine, Mahatma Gandhi Medical College, Sri Balaji Vidyapeeth University (Deemed to be), Pondicherry, India.

Lokesh Shanmugam
Department of Medicine, Mahatma Gandhi Medical College, Sri Balaji Vidyapeeth University (Deemed to be), Pondicherry, India.

View Book:- https://stm.bookpi.org/RDMMR-V6/article/view/4548

A Rare Complication of Poorly Controlled Diabetes Mellitus: Testicular Necrosis | Chapter 21 | Recent Developments in Medicine and Medical Research Vol. 6

 In this case, a 45-year-old male patient with diabetes was diagnosed with testicular necrosis. Past medical history suggests diabetes, with treatment taken seldom. The patient's right testicular enlargement has been gradually rising for three weeks. In the right testis, ultrasonography revealed an abscess with no vascularity. The orchiectomy on the right side was completed. Histopathology confirmed testicular necrosis. Torsion-induced testicular necrosis is a common condition that leads to orchiectomy. Patients with acute onset scrotal pain, which is frequently unilateral, occur in these cases. The testis is extremely painful on inspection, with red, angry-looking skin overlaying it. Diabetic people are prone to urinary tract infections and epididymo-orchitis. Testicular discomfort, fever, leucocytosis, and other symptoms are common in patients.

Testicular necrosis, on the other hand, is extremely rare. Long-term consequences of diabetes mellitus include retinopathy, nephropathy, and neuropathy. Patients with long-term diabetes, including both insulin-dependent and non-insulin-dependent diabetes mellitus, are susceptible to various consequences, which can result in substantial morbidity. Testicular necrosis is a fairly uncommon consequence of diabetes mellitus. There were no articles about testicular necrosis as a diabetes consequence when I searched the internet. A case of unilateral testicular necrosis as a consequence of diabetes mellitus is given for the first time. Accelerated microangiopathy in combination with inadequate blood glucose management most likely produced this rare consequence.

Author(S) Details

Parthasarathi Hota
Department of General Surgery, Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India.

View Book:- https://stm.bookpi.org/RDMMR-V6/article/view/4547