Association of High-Sensitive C-reactive Protein and Atherogenic Lipid Levels Among Group of University Students with Habitual Smoking | Chapter 14 | Current Practice in Medical Science Vol. 1

The inflammatory and cardiovascular disease (CVD) marker high-sensitive C-reactive protein (hs-CRP) is well-known. Blood levels of non-high density lipoprotein cholesterol (n-HDL-C) are closely linked to a lifetime risk of atherosclerotic CVD. According to certain theories, Hs-CRP and atherogenic lipids constitute a key component of cardiovascular disease (CVD), especially in smokers. Long-term smoking appears to be associated with high levels of plasma cholesterol, hs-CRP, and LDL-C. The purpose of the study is to assess the plasma levels of hs-CRP, lipid profile, and magnesium in a sample of college students who smoke often. Eighty guys who currently smoke were included in this cross-sectional investigation. The plasma hs-CRP was estimated using the latex immune turbidimetric technique, employing a spectrophotometer, and chemical techniques were employed to calculate the plasma lipid profile and magnesium (Biosystem 310). The plasma levels of hs-CRP, total cholesterol, and LDL-C increased significantly in the test group of students who have smoked for at least 10 years (P 0.05), while HDL-C levels decreased significantly (P 0.05). The results demonstrated that smoking caused substantial changes in hs-CRP and atherogenic lipids, two markers of cardiovascular disease risk in young male smokers.

Author(s) Details:

Ghada A. Elfadil,

Department of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan.

Elyasa M. Elfaki,

Clinical Laboratory Sciences Department, College of Applied Medical Science, Al-Qurayyat, Jouf University, Saudi Arabia.

Sulafa O. Madani,

Department of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan.

Ezeldine K. Abdalhabib,

Department of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan.

Abdelgadir Elmugadam,

Department of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan.

Please see the link here: https://stm.bookpi.org/CPMS-V1/article/view/7333

Vitamin D deficiency and Its Link with Inflammatory Markers in Women | Chapter 16 |Highlights on Medicine and Medical Science Vol. 2

 Aim: Vitamin D deficiency is a serious health problem that affects people of all ages, particularly elderly women. Menopause is a significant event in a woman's life. Women are becoming more susceptible to a variety of metabolic diseases as they get older. The purpose of this study is to determine serum vitamin D and hs-CRP levels in premenopausal and postmenopausal women.

Methods: The study included 500 female participants, with 400 pre- and postmenopausal women serving as cases and 100 serving as healthy controls. Vitamin D levels in serum were measured using a chemiluminescent microparticle immunoassay, and hs-CRP levels were measured using a latex-enhanced turbidimetric immunoassay. All female subjects were tested for serum estradiol (E2) using a competitive immunoassay method. SPSS software, version 22.0, was used to analyze the data. When pre- and postmenopausal women were compared to healthy control women, vitamin D levels were significantly lower and hs-CRP levels were significantly higher (p0.001). Serum estradiol levels were also significantly lower in postmenopausal women. We discovered a strong negative correlation between vitamin D deficiency and hs-CRP levels in both pre- and postmenopausal women.

Conclusion: Postmenopausal women are more likely than premenopausal women to be vitamin D deficient. Low-grade systemic inflammation has been linked to an increased risk of cardiovascular disease, diabetes, and metabolic syndrome in postmenopausal women.

Author (s) Details

Dr. Deepa Gupta
Department of Biochemistry, NAMO Medical Education & Research Institute, Silvassa, India.

Neelima Singh
University of Kota, Rajasthan, India.

View Book :- https://stm.bookpi.org/HMMS-V2/article/view/1789