A Comprehensive Review on Nutraceuticals and Its Impact on Healthcare | Chapter 7 | Pharmaceutical Science: New Insights and Developments Vol. 4

Nutraceuticals are bioactive products that merge the benefits of nutrition and medicine to enhance health and prevent chronic diseases. They play a crucial role in managing conditions associated with oxidative stress, including cardiovascular diseases, diabetes, inflammation, ophthalmic disorders, and immune-related illnesses. Often considered a bridge between food and medicine, nutraceuticals encompass herbal remedies, natural foods, specific nutrients, vitamins, dietary supplements, and functional foods such as soups, juices, cereals, and beverages. Nutraceuticals are broadly categorized into conventional and unconventional types. Conventional nutraceuticals, such as omega-3 fatty acids and dietary fiber, have well-established health benefits. In contrast, unconventional nutraceuticals are still under investigation for their potential therapeutic effects. While nutraceuticals offer numerous advantages, including improved overall health and reduced risk of chronic illnesses, they also pose potential risks, such as drug interactions, adverse side effects, and the possibility of overdose. As interest in nutraceuticals continues to grow, ongoing research is essential to fully understand their efficacy, safety, and role in modern healthcare.

 

Author (s) Details

 

Ismail. Y
Crescent School of Pharmacy, B. S. Abdur Rahman Crescent Institute of Science and Technology, GST Road, Vandalur, Chennai, Tamil Nadu, India.

 

Yuvarani T
Crescent School of Pharmacy, B. S. Abdur Rahman Crescent Institute of Science and Technology, GST Road, Vandalur, Chennai, Tamil Nadu, India.

 

Voleti Vijaya Kumar
Crescent School of Pharmacy, B. S. Abdur Rahman Crescent Institute of Science and Technology, GST Road, Vandalur, Chennai, Tamil Nadu, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/psnid/v4/4613

Effect of Diet on the Tendency for Stone Formation in Patients with Calcium Oxalate Stones in the Urinary Tract| Chapter 5 | Current Topics on Chemistry and Biochemistry Vol. 7

 Patients accompanying emergent calcium oxalate grains should trail a depressed-oxalate diet to prevent repetition. The aim concerning this study on patients accompanying calcium oxalate metals search out study the impact of able to be consumed calcium content on the formation of calcium oxalate crystal in excretion utilizing an artificial supersaturation study of new postprandial urine samples and to obey the plant structure of the crystal made utilizing reverse optical microscopy. The study was created as a potential interventional randomized crossover dispassionate trial accompanying periodic measures. Sixty patients accompanying calcium oxalate metals and no metabolic irregularities in excretion were acted with lithotripsy at a after second care center from May 2016 to May 2019. Following a 14-time journey fast, excretion samples were calm afterwards the patient was given either a reduced or extreme-calcium food for brunch, understood by a high-oxalate food four hours later.The ocular bulk principles and calcium-creatinine percentage of excretion samples obtained following a extreme calcium food are considerably above those acquired following a low calcium food (p<0.001). These findings were mirrored in the breadth, shape, and number of made crystals. During a supersaturation study of postprandial excretion samples following a extreme-oxalate diet, no crystal were made when excretion calcium levels were depressed. Kidney stone result is extensively affected by a extreme calcium consumption in the diet. Even when consuming a extreme-oxalate diet, a reduced-calcium food has a lower risk of provoking kind stones.

Author(s) Details:

Jim Joe,
Department of Biochemistry, Government Medical College Kottayam, Kerala, India.

Sathish Kumar Gopala,
Department of Urology, Government Medical College, Thiruvananthapuram, Kerala, India.

Please see the link here: https://stm.bookpi.org/CTCB-V7/article/view/9227

Anti-Inflammatory Priming Enhances the Anti-Erectile Dysfunction Efficacy of PDE5 Inhibitors | Chapter 18 | Issues and Developments in Medicine and Medical Research Vol. 3

 Background: Evidence for the role of low-grade systemic inflammation as a co-determinant of erectile dysfunction has been accumulating for some time. Inflammation and disturbance of local microcirculation may potentially prevent PDE5 (phosphodiesterase type 5) inhibitors from working to their full potential. The goal of the idea-generating pilot study described here was to see if reducing such pro-inflammatory contributions to the erectile dysfunctional milieu with the use of a food supplement could improve PDE5 drug efficacy.

Methods: Study Design: Prospective cohort pilot study (14 patients diagnosed with moderate erectile dysfunction) with an end-of-study comparison of final treatment outcomes vs. a random sample of recent history ED (erectile dysfunction) controls from the author's urology ward.

Treatment in a Group Background anti-inflammatory priming for one month (one 1-g tablet once day) with a dietary supplement with known anti-inflammatory and capillary protecting effects, followed by three months of alternating every-other-day treatment with 25-mg sublingual sildenafil or the dietary supplement.

Assessments included a purely exploratory comparison of the prospective cohort's end-of-study EEIF-5 mean scores with a sample of historical controls, as well as a comparison of the overall skewness of the cohort distribution of IIEF-5 (simplified International Index of Erectile Function) scores before and after the treatment period.

The IIEF-5 frequency distribution had a strong left skewness towards the end of the research when compared to the basal score distribution, indicating that reducing background inflammation could be beneficial. Prospective active cohort EEIF-5 mean scores vs. ED historical controls: 20.4 vs. 14.0.

Conclusions: The exploratory comparison of end-of-treatment mean IIEF-5 scores in the active cohort vs historic controls provides preliminary support for the idea that modifying the pro-inflammatory erectile dysfunctional milieu with the anti-inflammatory dietary supplement may have contributed to the overall efficacy of the anti-ED treatment and improved the 3-month efficacy of sublingual sildenafil. Further research is required to corroborate these early findings.

Author(S) Details

Ninfa Alessandra Giacalone
Urology Operative Unit, “Istituto G. Giglio” Foundation, Cefalù, Sicily, Italy.

Francesco Curto
Urology Operative Unit, “Istituto G. Giglio” Foundation, Cefalù, Sicily, Italy.

Mauro Raichi
Clinical Pharmacology, Bioinformatics and Statistics Consultant, Milan, Italy.

View Book:- https://stm.bookpi.org/IDMMR-V3/article/view/5479