Showing posts with label diabetic. Show all posts
Showing posts with label diabetic. Show all posts

Sunday, 30 March 2025

Age-Associated Variations in Vitamin D Levels among Diabetic and Non-Diabetic Men | Chapter 3 | Disease and Health: Research Developments Vol. 8

Background: The required quantities of exposure to sunlight differ from other seasons, as the majority of people suffer from reduced levels of vitamin D, especially during the winter season. The periods of exposure differ according to the seasons of the year, the place, terms of the skin exposed to the sun and the type of skin as well as the type of clothes, in the summer the best time For exposure is the middle of the morning or In the afternoon outside the peak of UV rays, while in the winter there are longer periods of exposure to the sun with the preference of the near time from the afternoon, it is important to establish a balance between the need for sunlight in order to produce what is appropriate for vitamin D and avoid the risk of a skin lesion with excessive exposure for the sun at the same time.

Where it is estimated that the appropriate time to exposure is about 5 to 10 minutes on most of the summer days, and 30 minutes as a maximum during the winter days, and it is preferable that the arms, legs and face are the areas exposed to sunlight, and the period of exposure to the sun may vary depending on the type of skin, and it is useful to know that there is Light than UV rays through Regular transparent windows.

Vitamin D is synthesized from precursors present at the surface of the epidermis and then undergo biotransformation which is achieved at the hepatocytes and finally by hydroxylation enzymes in the nephrons. Sunrays play a crucial role in the beginning of D vitamin formation processes, parathyroid hormone is an essential hormone secreted by parathyroid glands and plays a key role in the activation of D vitamin by renal alfa hydroxylase. Food sources of Vitamin D are also important for supplementation of the human body with some requirements.

Aim: This study aimed to compare the concentration of vitamin D in diabetic patients, and non-diabetic men and its association with age.

Patients and Methods: The current study started at the beginning of June 2018 and continued until the end of March 2019, at the outpatient unit in a special private hospital in Tikrit City - Iraq. Eighty men have been enrolled in the present study.

Results: Eighty men participated in the present study, distributed as 40 non-diabetic subjects as controls and 40 diabetic patients. The mean and standard deviation of D vit. levels of non-insulin-dependent diabetes and normal physically fit men show there is a significant reduction of D vit. Measurements of the diabetic men patients suffering from T2DM, (13.58 ± 5.29) as compared with control subjects, (19.95 ±6.5). There is a significant decrease in vit. D measurements of T2DM young patients. In T2DM patients less than 18 years old have a significant reduction in vitamin D concentration, (13.41 ± 5.1), as compared with T2DM patients aged 18-40 years, (17.23 ± 7.3). Measurements of vit. D. During heat season and compared to cold months. The evaluation of Vit. D. During hot months shows a significant rise (26.4 ± 7.1) in comparison with winter status (13.65 ± 4.2).

Conclusions: The present study concludes that, Vit. D levels show a highly important increment in hot months as compared with the winter season and there are significant reductions in the concentration of vitamin D in young age type 2 diabetic patients.

 

Author (s) Details

 

Abdulhadi Mohamed Jumaa
Department of Physiology, College of Medicine, Tikrit University, Iraq.

 

Meqdam Atiyah Khalaf
Department of Surgery, College of Medicine, Tikrit University, Iraq.

 

Hassan Yashar Hassan
Department of Physiology, College of Medicine, Tikrit University, Iraq.

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrd/v8/4623

Wednesday, 1 September 2021

A Case Report on Group “G” B-Hemolytic Streptococcus, a New Important Causative Organism of Localised Intra-Abdominal Abscess | Chapter 11 | New Frontiers in Medicine and Medical Research Vol. 4

 The "G" group Streptococcus is a common commensal bacteria that can be found in the skin, throat, gut, appendix, and female genital system. According to our review of the literature, we present the first reported case of a localised intra-abdominal abscess caused by Group g streptoccus (GGS), also seen for the first time in our institution, which is a rare but important cause when the post-operative pyrexia/symptoms do not settle down with rising counts after the requisite surgical procedure-drainage and antibiotic regimens. Blood cultures were negative in our case, but pus culture-liquid subcultures grew large colony gramme positive cocci on the first postoperative day, which were later identified as Group G Streptococcus (GGS) with the sensitivity pattern on the third postoperative day identifying the organism as large-so a good microbiology department team is required, which in our case was instrumental in the mammalian mammalian mammalian mammalian mammalian mammalian This case is being reported because it is unusual. It is gaining relevance as an organism for creating deep-seated abscesses in the body, especially the abdomen, which are generally many or as peritonitis. It is especially observed in diabetics/malignancies/respiratory infections/immunosuppressed/chronic leg ulcers/pet dogs at home. Another important reason for immediate and urgent drainage of abscesses caused by GGS infections that has been mentioned in the literature is that it can lead to a very serious streptococcal toxic shock syndrome with a very fulminant and rapid downhill course with GGS bacteremia having a high 30-day mortality rate of up to 15%.


Author (S) Details

Shiv Chopra
Department of General and Gastrointestinal Surgery, Indraprastha Apollo Hospital Delhi-Mathura Road, Sarita Vihar, New Delhi-110076, India.

V. K. Aneja
Department of Internal Medicine, Indraprastha Apollo Hospital, Delhi-Mathura Road, Sarita Vihar, New Delhi-110076, India.

Raman Sardana
Department of Internal Medicine, Indraprastha Apollo Hospital, Delhi-Mathura Road, Sarita Vihar, New Delhi-110076, India.

Leena Mehndiratta
Department of Internal Medicine, Indraprastha Apollo Hospital, Delhi-Mathura Road, Sarita Vihar, New Delhi-110076, India.

View Book :- https://stm.bookpi.org/NFMMR-V4/article/view/2890