Fatality of Cases by New Coronavirus Disease (COVID 19): A Case Study in the Mexican State of Guanajuato | Chapter 04 | New Horizons in Medicine and Medical Research Vol. 9

 The goal of this research is to explain the COVID-19 pandemic and report on fatalities in the Mexican state of Guanajuato until October 2, 2020.

The National Epidemiological Surveillance System Database from Mexico was used for this study. Age, sex, comorbidities (diabetes, COPD, asthma, hypertension, cardiovascular disease, immunosuppression, chronic renal disease, obesity, and smoking), date of death, and real-time reverse transcription polymerase test results were all collected. In statistical analysis, the Case Fatality Ratio, Chi-squared test, and P-value were used to show relationships between variables. The impact of comorbidities on death from COVID-19 was demonstrated using the odds ratio and 95 percent confidence intervals. The statistical relationships were also determined using a Bayesian network model. risk factors, comorbidities, and mortality There were 100,109 suspected cases, with 41.69 percent of them testing positive for SARS-CoV-2. COVID-19 discovered that being over 60 and male had a higher risk of death. In Guanajuato State, 1,457 fatalities (48.68 percent) happened in the Mexican Institute of Social Security, with a case fatality ratio of 15.63 percent; meanwhile, 1,260 deaths (42.10 percent) occurred in the Ministry of Health, with a case fatality ratio of 4.14 percent. Diabetes (OR 5.16, CI95 percent 4.77–5.59), chronic obstructive pulmonary disease (OR 6.34, CI95 percent 5.37–7.49), immunosuppression (OR 2.85, CI95 percent 2.17–3.76), cardiovascular disease (OR 4.20, CI95 percent 3.51–5.02), hypertension (OR 4.74, CI95 percent 4.39–5.11), chronic kidney disease (OR 6.27, CI95 percent 5.30–7.42), COVID-19 has an influence on death.

Age and sex were the two most important risk variables for mortality among COVID-19 patients in Guanajuato. Diabetes, COPD, immunosuppression, cardiovascular disease, chronic renal disease, obesity, and smoking, on the other hand, are all variables that increase the chance of mortality. On the other hand, comorbidities and risk factors are strongly linked. SARS-CoV-2 disease lethality is unaffected by HIV/AIDS, however asthma appears to be protective.


Author(S) Details

Efrain Navarro-Olivos
Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Gilberto Flores-Vargas
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Maria de Jesus Gallardo-Luna
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Francisco Javier Magos-Vazquez
Directorate of Health Services, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Daniel Alberto Diaz-Martinez
Directorate of Health Services, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Nicolas Padilla-Raygoza
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

View Book:- https://stm.bookpi.org/NHMMR-V9/article/view/6897

Clinical Picture of SARS-Cov-2 Infection in Children in Guanajuato State, Mexico: A Recent Study | Chapter 12 | Issues and Development in Health Research Vol. 7

 The goal of this study was to compare the signs and symptoms of COVID-19 with those of another respiratory virus in children.

Coronaviruses are members of the Coronaviridae family of the Nidovirales order. This virus proliferated faster in human airway epithelial cells than in tissue culture cells, indicating that it has a higher infectivity potential.

Research Design: Data from the General Directorate of Epidemiology's National Epidemiological Surveillance System were used to create a cross-sectional study. Place and Time of Study: From March to July 2020, all registrations in the database of confirmed and discarded COVID-19 cases from Guanajuato State, Mexico were examined.

A confirmed case was defined as someone who had fever, cough, and dyspnea, had travelled to a pandemic-affected nation or had contact with a confirmed case, and had a positive rRT-PCR test for SARS-CoV-2. The cases that were discarded had a negative rRT-PCR test. Clinical data was compared with Z for two proportions and P-value among individuals under the age of 18, of confirmed and rejected cases in the state of Guanajuato.

The sample includes 446 confirmed cases and 2,134 instances that were discarded. The average age of those confirmed was 9.60 5.46 years, while the average age of those excluded was 8.01 5.39 years (P.05). Males outnumbered females in both groups (P =.91). There are statistically significant differences between confirmed and rejected cases in fever, myalgia, arthralgia, and conjunctivitis (P.05).

Conclusion: The signs and symptoms of COVID-19 and another respiratory virus are identical. COVID-19's characteristics are similar to those of other viral infections, thus the diagnosis cannot be made solely on the basis of signs and symptoms.

Author(S) Details

Nicolás Padilla-Raygoza
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Gilberto Flores-Vargas
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Efraín Navarro-Olivos
Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

María de Jesús Gallardo-Luna
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

View Book:- https://stm.bookpi.org/IDHR-V7/article/view/4815

Relationship of Clinical Data and Confirmed Case of COVID-19, in the Mexican State of Guanajuato | Chapter 11 | Recent Developments in Medicine and Medical Research Vol. 10

 The goal was to assess clinical data in a population from the Mexican state of Guanajuato as a suspected case of COVID-19 with a positive rRT-PCR result reported till October 2, 2020.

Introduction: One of the main concerns since the start of the new coronavirus pandemic in Wuhan, China, at the end of 2019, has been getting a correct diagnosis. Fever is the most common symptom of COVID-19 infection, however it can also be found in other viral infections.

Study Design: This is a cross-sectional study based on data from the General Epidemiological Directorate's National Epidemiological Surveillance System and the Mexican Secretary of Health's National Epidemiological Surveillance System.

Sample registries from confirmed and discarded COVID-19 cases will be kept in the database until October 2, 2020.

Methodology: A total of 100,919 registries were examined. The results of the rRT-PCR test were missing in 810 of them, thus they were eliminated. A confirmed case of COVID-19 is a person who has a positive rRT-PCR test for SARS-CoV-2, regardless of the clinical data presented. A suspected case of COVID-19 is a person who has a positive rRT-PCR test for SARS-CoV-2 and is accompanied by at least one of the following: myalgia, arthralgia, odynophagia, chills, chest pain, rhinorrhea, an Age, sex, and clinical data were all recorded, as well as the SARS-CoV-2 rRT-PCR result. The effect of clinical data on positive rRT-PCR was investigated using logistic regression.

A total of 100,109 registries were examined. SARS-CoV-2 was detected in 41,734 of them. Fever (OR 1.72, CI95 percent 1.68 to 1.77), cough (OR 1.70, CI95 percent 1.66 to 1.74), and odynophagia (OR 1.71, CI95 percent 1.66 to 1.75) were all found to have a larger effect on a positive rRT-PCR test. The result of the rRT-PCR test was unaffected by cyanosis.

COVID-19 has no clinical data that can be used to diagnose it. In confirmed instances, the clinical data is similar to that of other respiratory viral infections.

Author(S) Details

Nicolas Padilla-Raygoza
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Gilberto Flores-Vargas
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

María de Jesús Gallardo-Luna
Department of Research and Technological Development, Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

Efraín Navarro-Olivos
Directorate of Teaching and Research, Institute of Public Health from Guanajuato State, Guanajuato, Mexico.

View Book:- https://stm.bookpi.org/RDMMR-V10/article/view/4633