Ionic Liquid-based Schiff Base Ligand for the Synthesis of Fe(III) and Cr(III) Metal Complexes and Their Antibacterial Studies | Chapter 5 | Recent Developments in Chemistry and Biochemistry Research Vol. 2

Fe(III) and Cr(III) complexes derived from an ionic liquid-based Schiff base, 1-{2-(2-hydroxy-5-chlorobenzylamine)ethyl}-3-ethylimidazolium were characterized and established by various analytical and spectroscopic techniques such as ESI-MS, UV-Visible, FT-IR, 1H NMR, elemental analysis and magnetic susceptibility measurements. Based on these spectral data octahedral geometry was suggested for the both complexes. The Schiff base ligand and its complexes were screamed for in vitro antibacterial activities against gram positive and gram negative bacteria to assess their effects. Cr(III) complex showed higher activity than the Fe(III) complex against the tested gram positive and gram negative bacteria.

Author(s) Details:

Sanjoy Saha,
Department of Chemistry, Kaliyaganj College, Kaliyaganj-733109, India.

Please see the link here: https://stm.bookpi.org/RDCBR-V2/article/view/14113

Study on Synthesis and Antibacterial Efficacy of Chloro-Substituted 1,3-Thiazines | Chapter 10 | Recent Trends in Chemical and Material Sciences Vol. 2

 Thiazines are valuable units in medicinal and pharmaceutical chemistry, with a wide range of biological activity described. This prompted us to use thiourea, phenyl thiourea, and diphenyl thiourea to make chloro-substituted thiazines from 2'-hydroxy-3',5'-dichloro-4-4'-chlorophenyl chalcone. In this series, we made 4-(2'-hydroxy-3',5'-dichlorophenyl)-6- (4'-chlorophenyl)-4'-chlorophenyl)-4'-chlorophenyl)-4'-chlorophenyl)-4'-chlorophenyl)-4'-chlorophenyl)-4 4-(2'-hydroxy-3',5'-dichlorophenyl)-6-(4'-chlorophenyl)-2-imino-1,3-thiazine and 4-(2'-hydroxy-3',5'-dichlorophenyl)-4-(4'-chlorophenyl)-4-(4'-chlorophenyl)-4-(4'-chlorophen 4-(2'-hydroxy-3',5'-dichlorophenyl)-2-iminophenyl-1,3-thiazine and 4-(2'-hydroxy-3',5'-dichlorophenyl)-2-iminophenyl-1,3-thiazine from thiourea and phenyl thiourea, respectively. -6-(4'-chlorophenyl) Diphenyl thioure is converted to -2-iminophenyl-3-phenyl-1,3-thiazine. The antibacterial properties of newly synthesised chloro-substituted 1,3-thiazines were tested against Gram positive pathogens Staphylococcus aureus and Streptococcus sp., as well as Gram negative pathogens Pseudomonas sp. and Salmonella typhi. The UV, IR, and NMR spectrum investigations of all of these substances were used to describe them.

Author (S) Details

A. V. Gajbhiye
Department of Chemistry, MGV's A.S.C. College, Nampur-423 204, India.

View Book :- https://stm.bookpi.org/RTCAMS-V2/article/view/2911