Stem Cell Breakthroughs: A Cure in Sight? | Chapter 4 | Medical Science: Trends and Innovations Vol. 4

Stem cells, characterized by their remarkable abilities for self-renewal and differentiation, are at the forefront of regenerative medicine, offering transformative potential for treating a spectrum of degenerative diseases. The journey of stem cell therapy began in 1958 and has evolved significantly, with pivotal advancements such as the isolation of embryonic stem cells in 1998 and the creation of induced pluripotent stem cells [iPSCs] in 2006. Different stem cell types—ranging from hematopoietic to mesenchymal and neural stem cells—show promise in addressing conditions like neurological disorders, autoimmune diseases, and haematological disorders. Despite their therapeutic potential, ethical dilemmas remain a significant challenge, particularly concerning embryonic stem cells, which prompt ongoing debates about the moral implications of their use. As the field progresses, addressing safety, efficacy, and equitable access to stem cell therapies is critical. Innovative delivery systems and methodologies are being developed to enhance the effectiveness of these therapies while minimizing associated risks. Looking ahead, research will focus on harnessing the full potential of stem cells, elucidating the molecular pathways that govern their differentiation, and navigating the ethical landscape. Through these efforts, we may pave the way for ground-breaking treatments that could redefine the future of healthcare and improve patient outcomes across various conditions.

 

Author (s) Details

Avi Mittal
Pt. BD Sharma PGIMS, Rohtak, India.

Nikita Malik
Pt. BD Sharma PGIMS, Rohtak, India.

 

Kavita Sihmar
Pt. BD Sharma PGIMS, Rohtak, India.

 

Nazuk Soni
Pt. BD Sharma PGIMS, Rohtak, India.

 

Priyanka
Pt. BD Sharma PGIMS, Rohtak, India.

 

Hemant Kumar
Pt. BD Sharma PGIMS, Rohtak, India.

 

Ajay
Pt. BD Sharma PGIMS, Rohtak, India.

Sujal
Pt. BD Sharma PGIMS, Rohtak, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/msti/v4/3313

Stem Cell a Solution May Help to Treatment for Pandemic COVID-19 | Chapter 04 | Research Aspects in Biological Science Vol. 2

 The effectiveness of IV mesenchymal cell transplantation has not been presented with a final conclusion that allows scientists to recommend it as the only treatment, although investigation in various pathologies revealed a very favourable immune reaction, modulati Furthermore, it clearly illustrates a regeneration of it (which is the same) that has powerfully captured the attention of doctors when treating autoimmune, degenerative, and chronic pathologies that have no palliative therapies to date, such as SLE, post-infarction heart disease, chronic arthritis, Alzheimer's, and many other laboratory tests were performed. owing to the urgent requirement of disappointed patients due to a lack of therapy choices, mesenchymal cells were used to treat them. We have advised managing cytosines by the transplantation of mesenchymal cells, since they are the major causes of issues owing to their higher systemic reactivity, because the pneumonias generated by this novel virus are fast advancing and lethal, with little effective therapy. We investigated the use of stem cells to improve patient quality of life in a variety of diseases.

Author(S) Details

F. G. Mistrih
Donka Avdaloff Clinic, Chile.

N. G. Mistrih
Clinica Donka Avdaloff, Chile.

G. Eghon
Scientific Medical Association Chile (ASOCIMED), University of Chile, Chile.

View Book:- https://stm.bookpi.org/RABS-V2/article/view/6704

Antimicrobial Potential of Hemolymph Lectin and Solvent Extracts of Tissues of Marine Crab, Atergatis integerrimus against Fish and Clinical Pathogens | Chapter 9 | New Visions in Biological Science Vol. 7

 Marine crabs are a rich source of bioactive chemicals with pharmacological capabilities, and antibacterial efficacy against clinically important infections has been established. The antibacterial activity of solvent extracts of different tissues and hemolymph lectin of Atergatis integerrimus against four fish and human pathogenic bacteria and four fungal pathogens is investigated in this study. E. coli was sensitive to the majority of the solvent extracts, while Enterococcus faecalis was particularly sensitive to the chloroform extract of the carapace and the butanol extract of the hemolymph. With butanol extract of entire body against Streptococcus mutans and Bacillus subtilis, the maximum zone of inhibition was recorded. The butanol extract of ovary, whole body, and crude hemolymph showed the greatest zone of inhibition against Vibrio harveyi when evaluated against the diverse tissue extracts. The acetone and ethylacetate extracts of hepatopancreas were toxic to Aeromonas hydrophila. The growth of Aspergillus flavus and Aspergillus niger was suppressed by butanol extracts from various tissues. Candida albicans growth was inhibited to considerable extent by chloroform, ethyl acetate, and butanol extracts. Almost all of the tissue extracts tested were resistant to Pencillium notatum. Based on preliminary research, a small number of pathogenic bacteria and fungi were chosen to investigate the effect of the pure lectin of Atergatis integerrimus, and antimicrobial activity was observed in all pathogens tested at a concentration of 100 g. As a result of our research, we can conclude that the tissue extract contains bioactive chemicals that particularly target pathogenic microorganisms, and that the isolated lectin, a crab defence molecule, has antimicrobial properties as well.

Author(S) Details

T. Elayabharathi
Department of Zoology, Holy Cross College (Autonomous), Nagercoil, India.

J. Vinoliya Josephine Mary
Department of Zoology, Holy Cross College (Autonomous), Nagercoil, India.

S. Mary Mettilda
Department of Zoology, Holy Cross College (Autonomous), Nagercoil, India.

Balaraman Deivasigamani
CAS in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai-608502, Tamilnadu, India.

View Book:- https://stm.bookpi.org/NVBS-V7/article/view/5124