Showing posts with label Semen parameters. Show all posts
Showing posts with label Semen parameters. Show all posts

Friday, 27 January 2023

Use of Micronutrients for Treatment of Idiopathic Abnormal Sperm Parameters| Chapter 7 | Current Overview on Disease and Health Research Vol. 9

 The presnt study aimed to look at the possible effects of micronutrients on semen parameters including sperm count, motility, and morphology to improve male infertility. WHO defines infertility as the inability to achieve pregnancy within 12 months of regular sexual intercourse for couples in conception. Infertility affects 13–20% of couples in Poland and around the world, regardless of race or ethnicity. This study started from the 1st of March 2016 until 30th of November 2016 (6 six months was the period of taking the treatment) while the duration time of the study including the follow up and the examination period was 9 nine months.

In this clinical trial included male subjects aged from 20 to 60 years with at least 1 year of infertility and abnormal semen analysis who received 3 -6 months’ treatment with a Cyclofert men that contains (l-carnitine l-tartarate 1g, N – Asetyl - cysteine 600 mg, 40 mg zinc, Lycopene 20 mg, 60 mg vitamin E, 200 mg vitamin C, 80 mg glutathione, 200 g selenium, 100 mg coenzyme Q10 and 400 g folic acid. Theses micronutrients were given in a form of two tablets/ twice a day for 6 months). Sperm parameters (count, motility, and morphology) and pregnancy incidence were monitored before and after treatment. After three and six months of treatment, the data gathered indicated that there was an overall progressive motility. Furthermore, compared to the untreated group, the sperm count rose by 64% after three months and 88% after six months ( = 0.00, 1, at P 0.05). Additionally, treatment for three and six months markedly improved the morphology of the sperm (p 0.05). Following six months of treatment, 30% of women were able to become pregnant thanks to these beneficial changes. However, the length of treatment has a direct correlation with each of these improvements. The pregnancy incidence has been increased compared to the untreated group. This treatment improved also the pregnancy status in which it caused an elevation in the number of pregnant spouses compared with untreated ones.


Thursday, 24 September 2020

Recent Research on Semen Abnormality Patterns and Parameters in Male Partners of Infertile Couples in Dakar (Senegal) | Chapter 3 | Research Trends and Challenges in Medical Science Vol.5

 Introduction: Inter individual variation for semen on analysis is well known. Therefore, Semen profile

is not the same in individuals from different geographic locations, environments, ways of life, and
populations. It is important for a laboratory to have an idea of the semen profile of its population,
especially for those who present with infertility. The aim of this study was to draw the pattern of semen
abnormalities in male partner of infertile couple in Dakar, Senegal.
Materials and Methods: A retrospective study of all the semen samples of male partners of infertile couples submitted for analysis in the laboratory of Cytogenetic and Reproductive Biology of Dakar at  the University Teaching hospital from January 2013 to June 2014.
Results: A total of 262 male semen analyses were reported. Analysis was performed according to
WHO, 2010 manual for examination of human semen. Our study reveals that 80.9% of men in infertile
couples present an abnormality in sperm pattern. The main one is oligoasthenoteratonecrozoospermia (20.2%), followed by azoospermia, (14.1%), asthenonecrospermia (10.3%) and asthenoteratonecrozoospermia (10.3%). Leucocytospermia was found in 57.8%. Teratozoospermia (80.9%) was the most associated abnormality, followed by necrozoospermia (76.2%). Low sperm count under 5 million per ml concerned 27.7% of the patients, and 11.2% patients had low ejaculate volume. Nearly 42.1% of the male partners are potential candidates for Assisted Reproductive Technology for male infertility.
Conclusion: The high rate of semen abnormality in patients of infertile couples and consequently the
high rate of potential candidates to Assisted Reproductive Technology for male infertility are important
reasons for taking into account rigorously the male subject if we want to improve fertility rate in our
context. The pattern of the specific abnormalities found is precious clues to guide management of
these patients.

Author (s) Details

Mama Sy Diallo
Laboratory of Cytogenetic and Reproductive Biology, University Teaching Hospital Aristide Le Dantec, Dakar, Senegal.

Abdoulaye Séga Diallo
Laboratory of Cytogenetic and Reproductive Biology, University Teaching Hospital Aristide Le Dantec, Dakar, Senegal.

Pyrrhus Fotso
Laboratory of Cytogenetic and Reproductive Biology, University Teaching Hospital Aristide Le Dantec, Dakar, Senegal.

Yoro Diallo
Department of Urology, Faculty of Health Sciences, University of Thies, Thies, Senegal.

Babacar Diao
Urology and Andrology Unit, University Teaching Hospital Aristide Le Dantec, Dakar, Senegal.

Oumar Faye
Laboratory of Cytogenetic and Reproductive Biology, University Teaching Hospital Aristide Le Dantec, Dakar, Senegal.

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https://bp.bookpi.org/index.php/bpi/catalog/book/264