Phthalocyanine complexes under the research interest belong
to the porphyrin-like compounds with a structure that is described as flexible
for chemical alterations and unique photo physicochemical properties for the
most challenging application fields such as biomedicine and ecology. As a
result of visible or near-infrared light excitation in the oxygen atmosphere,
cytotoxic oxygen species such as molecular singlet oxygen and others have been
produced. The pathogenic cells as a target for these reactive oxygen species
could be inactivated and the curative process stand up. The book presents a
number of new original phthalocyanine complexes and their studies as
photosensitizers for inactivation on pathogenic cells (bacteria, fungi, and
viruses). The results showed our efforts to reduce the main limitations of the
known photosensitizers with a special focus on the hydrophobicity,
drug-delivery, uptake and selectivity of phthalocyanines and not the last the
dark toxicity of the composite containing photoactive compound for the optimal
PDT-efficiency.
Author (s) Details
Vanya Mantareva
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian
Academy of Sciences, Sofia, Bulgaria.
Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49970-20-5
