Liver Abscess: An Update on Current Management | Chapter 5 | Medical Science: Recent Advances and Applications Vol. 1

Liver abscess is a rare condition that causes pain over the right hypochondrium with fever. Liver abscesses are classified into amoebic liver abscesses and pyogenic liver abscesses. Diagnosis is commonly confirmed by performing an ultrasound or computerized tomography. The management of liver abscesses has seen a trend toward minimally invasive procedures like percutaneous drainage and intravenous antibiotics. For abscesses that are larger than 5cm, percutaneous drainage of the abscess is considered the gold standard treatment. Percutaneous drainage can be divided into percutaneous catheter drainage and percutaneous aspiration. Surgical drainage can be divided into open and laparoscopic drainage. In this chapter, the management of liver abscesses was examined, especially the role of percutaneous drainage, includes percutaneous catheter drainage, percutaneous aspiration, and surgical drainage.

A comprehensive literature review was conducted using PUBMED, the Cochrane database of systemic reviews, Google Scholar, and Semantic Scholar looking for randomized control trials, non-randomized trials, observational and cohort studies, clinical reviews, systemic reviews, and meta-analyses from 1990 to 2025. Currently, percutaneous drainage of liver abscess is the first-line interventional procedure that is performed for patients with liver abscesses. Open surgical drainage is rarely performed now. The use of percutaneous catheter drainage and antibiotics has led to a 90% success rate. Early diagnosis and prompt initiation of treatment are critical, as they significantly reduce morbidity and mortality.  

 

Author (s) Details

 

Kumar H.R.
Department of Surgery, Taylors University School of Medicine and Health Science, 47500 Selangor, Malaysia.

 

Please see the book here:- https://doi.org/10.9734/bpi/msraa/v1/4970

Prevalence of Amoebic Liver Abscess (ALA) for IgG Anti-body Titers among Patients in Bangui, Central African Republic | Chapter 5 | Current Progress in Medicine and Medical Research Vol. 3

This member determines the predominance of ALA and the titer of IgG anti amoebic in inmates suspected accompanying ALA in Bangui. In addition, we also analyzed the results concerning the sex age of the things and other risk determinants. The diagnosis of amebic liver abscess is occasionally difficult because its clinical exhibitions are highly changeable. In areas of endemicity, amebic liver swelling should always be doubtful in a patient with turmoil, weight loss, and right superior quadrant intestinal pain and tenderness.A cross localized study was performed whereby all dispassionate or suspected ALA victims’ who were admitted to the National Laboratory middle from two points January 2018 - October 2020. The diagnosis of ALA was doubtful based on clinical syndromes of; fever, intestinal pain (usually in the right hypochondrium or large stomach) and clinical signs of hepatomegaly and/or tender liver accompanying or without jaundice and intestinal ultra-sonography. The higher antitoxin titer response against in ALA subjects could be exhibitive of a more intense engagement of the invulnerable system accompanying the pathogen in the liver during obtrusive disease. ALA inmates’ IgG antibody titers were calculated by Indirect Hemmaglutination Assay and Chi-square test was used. A total of 1249 ALA patients were contained, among whom 570 (45.64%) were definite. Of these, 244 (42.08%) had titer 1:160 or less, 223 patients’ (39.13%) had titer ranging from 1:320 to 1:640 and 103 sufferers (18.07%) had strong titer grazing from 1:1280 to 1:2560. The association betwixt antibody titer results, age and sex was no meaningful (p = 1.0000). Our findings display a high prevalence of ALA and show no meaningful difference 'tween the sex and age ALA subjects. Sex dependent differences resistance and resistance to many contaminations in particular amoebiasis disease enhance unquestionably an growing field of interest.

 Author(s) Details:

Wilfrid Sylvain Nambei,

Department of Biomedical Sciences, Faculty of Health Sciences, Bangui, Central African Republic (CAR).

Edwige Régina Kodia-Lenguetama,

National Center of Blood Donors’, Ministry of Public Health, Bangui, Central African Republic (CAR).

Junior Nguerenam-Ouefio,

Department of Biomedical Sciences, Faculty of Health Sciences, Bangui, Central African Republic (CAR).

Please see the link here: https://stm.bookpi.org/CPMMR-V3/article/view/11238

Management Issues in Paediatric Liver Abscesses | Chapter 12 | New Frontiers in Medicine and Medical Research Vol. 4

 Background: Liver abscesses continue to be a major source of morbidity in children, with signs of an increase in their occurrence. Evidence-based care would be guided by an assessment of the clinical profile and management outcomes of paediatric liver abscess.

The goal of this study is to see how physical aspects of paediatric liver abscesses influence intervention and treatment outcomes.

Methods: From February 2011 to August 2016, all LA patients were managed in a retrospective, observational cohort study. Symptoms, possible predisposing factors, diagnosis technique, interventions, and length of stay were all collected and examined. The study's therapy was guided by the lesion's sonographic features.

During this time, thirty-two patients with an average age of 5.52 years were treated. Fever (25, 78 percent), right hypochondrium discomfort (19, 59 percent), abdominal distension (4, 12.5 percent), subacute intestinal obstruction (2, 6.25 percent), and peritonitis were the most common clinical characteristics (2, 6.25 percent ). Abscesses ruptured in three patients. Three individuals responded well to conservative therapy. USG guided needle aspiration was successful in five people with a size of less than 100ml. Pigtail insertion was required in 21 patients with larger lesions. A laparotomy was performed on three people. Severe sepsis and coagulopathy claimed the life of one patient. The remaining patients were all released.

Conclusions: In children, LA is a significant cause of morbidity. If not addressed, it might lead to rupture and death. Positive outcomes may be achieved if there is a high level of suspicion, early screening, and proper intervention in form-tailored management.

Author (S) Details

Digamber Chaubey
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Anand Pandey
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Piyush Kumar
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Archika Gupta
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Jiledar Rawat
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Ashish Wakhlu
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

Shiv Narain Kureel
Department of Pediatric Surgery, King George’s Medical University, Lucknow, Uttar Pradesh, India.

View Book :- https://stm.bookpi.org/NFMMR-V4/article/view/2891