Reporting of Adverse Drug Reaction by Pharmacist in Pharmacovigilance Programme of India: Perspective | Chapter 8 | Current Overview on Pharmaceutical Science Vol. 7

 This division aims to analyze the newsgathering by pharmacist in Pharmacovigilance Programme of India (PvPI). The druggist serves as a crucial point of contact 'tween patients and healthcare specialists. They supply medicines similarly a prescription or, when constitutionally permitted, peddle them buyable without a prescription. Individual Case Safety Reports (ICSRs) submitted by pharmacists instinctively to the NCC-PvPI were extracted from the computerized data in system of July 2011 to December 2014. This chapter resolved these reports for patients Sex, Age and Seriousness of the responses, etc. The pharmacist can help the development of an persuasive Pharmacovigilance system not only in India, but about the world.

Author(s) Details:

I. Kaur,
Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Government of India, India.

V. Kalaiselvan,
Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Government of India, India.

R. Kumar,
Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Government of India, India.

P. Mishra,
Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Government of India, India.

A. Kumari,
Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Government of India, India.

G. N. Singh,
Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Government of India, India.

Please see the link here: https://stm.bookpi.org/COPS-V7/article/view/9700

An Assessment of Educational Intervention to Improve Knowledge, Attitude and Practice of Pharmacovigilance among Nursing Staff in Tertiary Care Hospital | Chapter 4 | Technological Innovation in Pharmaceutical Research Vol. 9

The purpose of this study was to 1) examine nursing staff knowledge, attitude, and practise, as well as to evaluate the impact of educational intervention. 2) a. To address concerns about ADR reporting, such as nervousness, legal obstacles, and a lack of confidence, among other things. c. To improve ADR reporting by training nursing personnel on how to report ADRs and how to fill out the ADR reporting form. Material and Methods: Before and after an educational intervention in a tertiary care hospital, nursing staff were given a questionnaire regarding knowledge, attitude, and practise (KAP). The collected data was statistically analysed. As a result of the training delivered in numerous sessions, KAP among nursing workers has improved. In comparison to the pre-training session, they properly recognised who can report ADR 96% of the time (69 percent ). After training, 71 percent responded yes to pharmacovigilance as a means of ensuring the safe use of drugs, compared to 54 percent before. 94 percent of nursing personnel correctly identified the scale to be used for causality assessment in PvPI questions, compared to 79 percent before training. After training, the majority of them agreed that all ADRs should be reported, not only those that are unknown or harmful. In questio, there has been a substantial improvement. Conclusion: As a result of the educational intervention, KAP among nursing workers has greatly improved.

Author(s) Details

Dr. Sadhana Hingorani
Department of Pharmacology, SMIMER, Surat, India.

Dr. Chaitali Mehta
Department of Pharmacology, SMIMER, Surat, India.

Paresh Gajera
Department of Pharmacology, SMIMER, Surat, India.

S. K. Srivastava
Department of Pharmacology, SMIMER, Surat, India.

View Book :- https://stm.bookpi.org/TIPR-V9/article/view/2517

Centre-based Evaluation of Heamatological and Some Biochemical Effects of the Initial Phase of Anti-tuberculosis Therapy in Bayelsa State | Chapter 12 | Technological Innovation in Pharmaceutical Research Vol. 1

 The aim of this study was to determine the adverse effects of anti-tuberculosis drugs on blood and some biochemical parameters in patients with primary tuberculosis infection.

Study Design: This study used a non-probability (purposive) sampling method.

The research was performed at the Tuberculosis and Leprosy Referral Hospital's Chest Clinic in Yenagoa, Bayelsa State, Nigeria. From July 2017 to April 2018, this research was carried out.

Methodology: Tuberculosis patients were detected using normal clinical diagnostic methods and confirmed in the laboratory using acid quick bacilli as a preliminary test and Gene-Xpert® as a confirmatory test for Mycobacterium tuberculosis. At the Tuberculosis and Leprosy Referral Hospital in Yenegoa, Bayelsa State, 44 tuberculosis patients met the study's inclusion and exclusion requirements and completed the study. For two months, qualifying patients were given the required daily dose of a single drug combination (rifampicin-150 mg, isoniazid-75 mg, pyrazinamide-400 mg, and ethambutol-275 mg) based on their bodyweight. At baseline, week 4, and week 8, blood was drawn and checked for complete blood count, liver enzymes, Alkaline phosphatase (ALP), Alanine transaminase (ALT), Aspartate aminotransferase (AST), Total proteins, Bilirubin, and Cholesterol. Using a statistical kit for social sciences, the data were descriptively analysed (SPSS 21).

Results: During the intensive therapy process, alanine aminotransferase and alkaline phosphatase levels significantly increased (P=0.5). Total cholesterol and albumin levels both decreased dramatically (P=0.5). The WBC was also significantly lower (P0.05) in week 0 (12.451.35), week 4 (8.930.42), and week 8 (7.700.34), while the RBC was significantly higher (P0.05); RBC: week 0 (4.020.12), week 4 (4.590.12), and week 8 (4.820.10). There were no major increases in aspartate aminotransferase, total protein, or total bilirubin, and haematological changes were observed, but they were not serious enough to cause the therapy to be stopped.

Conclusion: The study's findings indicated improvements in full blood count and certain biochemical parameters, but not to the degree that therapy should be stopped.

Author (s) Details

Bonsome Bokolo
Department of Pharmacology, Faculty of Basic Medical Sciences, Niger Delta University, Bayelsa State, Nigeria.

Ozakieoniso James Kemelayefa
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Niger Delta University, Bayelsa State, Nigeria.

Ozakieoniso James Kemelayefa
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Niger Delta University, Bayelsa State, Nigeria.

Prof. Fidelis Ching Poh
Department of Pharmacology, Faculty of Basic Medical Sciences, Niger Delta University, Bayelsa State, Nigeria.

View Book :- https://stm.bookpi.org/TIPR-V1/issue/view/38

Recent Development of Adverse Drug Reaction Reporting and Drug Safety in India | Chapter 16 | Trends in Pharmaceutical Research and Development Vol. 6

India has recently developed several aspects related to pharmaceutical safety, such as tracking and reporting of adverse drug reactions. The pharmacovigilance programme implemented in India for the enhancement of pharmaceutical services results in a patient's quality of life. In order to maintain safety concerns, it is very difficult to build awareness of drug-related problems. Numerous adverse drug reactions in India have been recorded. By following rational substance use and genuine treatment patterns, the attentive role of healthcare practitioners, other healthcare professionals and non-healthcare professionals in the tracking and reporting of ADRs may be strengthened. These effects minimise medication failure, improvements in drug adherence, and enhance the safety of the drug.

Author (s) Details

Dr. H. B. Kavya
Sree Siddaganga College of Pharmacy, Karnataka, India.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/363