Saturday, 4 July 2020

Experiments on the Seroprevalences and Associated Factors of Viral Infections (HIV, Hepatitis B and C) among Pregnant Women Attending Antenatal Care at the Yaoundé Central Hospital | Chapter 3 | New Insights into Disease and Pathogen Research Vol. 5

A viral infection is a proliferation of a harmful virus inside the body. HIV infection, viral hepatitis B (HBV) and C (HCV) constitute a public health problem. The objective of this study was to assess seroprevalences and associated factors of these infections among pregnant women. We carried out a cross-sectional and analytical study. We consecutively enrolled 360 women attending ANC. Blood samples were collected to screen for HIVAb, HBsAg and HCVAb through rapid diagnostic tests, and confirmed at the “Centre Pasteur” laboratory of Cameroon. The mean age was 27.99 +/- 5.63 years, ranging from 15 and 47 years. The prevalence of HIVAb, HBsAg and HCVAb were 13.1% (n = 47), 9.4% (n = 34) and 1.7% (n = 6) respectively. We had 1.4% and 0.6% of HIV/HBV and HIV/HCV coinfections respectively. Independent risk factors associated with HIV were: The level of primary study (OR: 7.97; 95% CI = 2.23 - 28.49; P = 0.001) and multiple sexual partners (OR: 4 79; 95% CI = 1.79 - 12.79, P = 0.002). Multiple sexual partners was the Independent risk factor associated with HBsAg (OR: 11.62; 95% CI = 5.057 - 26.731; P = <0.001). No factor was associated with HCVAb.  Increased awareness, promotion of screening and / or treatment of infections and immunization against HBV in the general population and in women of childbearing age in particular, would reduce their impact and therefore prevent their horizontal and vertical transmission.

Author(s) Details

Dr. Florent Ymele Fouelifack
Obstetrics and Gynecology Unit of the Yaoundé Central Hospital, Cameroon and Department of Obstetrics and Gynecology, Higher Institute of Medical Technology of Nkolondom, Yaoundé, Cameroon and Research, Education and Health Associative Group GARES-Falaise, Dschang, Cameroon.

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