Frequency of Diabetic Foot Ulcer in Patients with Diabetes Mellitus: A Study at Saint Francis Referral Hospital, Morogoro-Tanzania | Chapter 10 | Achievements and Challenges of Medicine and Medical Science Vol. 8

Introduction: Diabetic foot ulcer is a common complication of Diabetic mellitus. Uncontrolled hyperglycemia leads to diabetic foot ulcers (DFU), which eventually results in amputation. Prevention and management of DFU requires a multi-disciplinary to improve DFU care.

Methodology: The study was conducted at St. Francis Referral Hospital a semi-urban health institute in the southwestern part of Tanzania. A cross-section retrospective study was conducted at Saint involving the hospital information of the patients who had foot ulceration. Data were analyzed by using the Statistical Package for Social Sciences (SPSS version 26).

Results: During the 12 months, DFU admission was found to be 19.14%. The 5th decade was the predominant age group which is 32.0% and the 9th decade was the least of all. There was a relatively high mortality rate (15.1%). The most identified factor for unfavorable outcomes was the presence of infection and severity of wound whose both P-values were statistically significant (0.010 and 0,027 respectively).

Conclusion: There is a need for diabetic foot care improvement involving reversed clinical patient visits in remote rather than the patients attending hospitals. The management and designing of this protocol should be in a multidisciplinary approach, involving surgeons, physicians, physiotherapists, nutritionists as well as nurses at the hospital level. Emphasis should be on proper assessment and grading of the ulcer severity to enable DFU prevention and proper management.

 

Author (s) Details

 

Theresia A. Karuhanga
Department of Surgery, Faculty of Medicine, Saint Francis University College of Health and Allied Sciences, P.O. Box 175, Ifakara, Tanzania and Department of Surgery, Saint Francis Referral Hospital, P.O. Box 73, Ifakara, Tanzania.

 

Claus Thomas
Department of Miclobiology, Faculty of Medicine, Saint Francis University College of Health and Allied Sciences. P.O. Box 175, Ifakara, Tanzania.

 

Philbert Madoshi
Department of Miclobiology, Faculty of Medicine, Saint Francis University College of Health and Allied Sciences. P.O. Box 175, Ifakara, Tanzania and Department of Public Health, Faculty of Medicine, Saint Francis University College of Health and Allied Sciences, P.O. Box 175, Ifakara, Tanzania.

 

Sakurani T Balthazary
Department of Biochemistry and Clinical Physiology, Faculty of Medicine, Saint Francis University College of Health and Allied Sciences, P.O. Box 175, Ifakara, Tanzania.

 

Please see the book here:- https://doi.org/10.9734/bpi/acmms/v8/3560

A Rare Case: Treatise on Classical Hodg-kin Lymphoma-Mixed Cellularity Stage 3B with Vincristine-Induced Peripheral Neuropathy | Chapter 12 | Medical Research and Its Applications Vol. 6

Classical Hodgkin lymphoma is a lymphatic system cancer that affects 2-1 cases per 100,000 people annually in developed nations. We report a unique case of vincristine-induced peripheral neuropathy associated with acute pan-creatitis in a 16-year-old male patient suffering from classical Hodgkin lym-phoma (CHL) with the primary symptom of bilateral cervical lymphadenopathy. However, upon diagnosis, this youngster was found to have cervical lympho-ma, which differs from the other symptoms of the disease. Diagnosed in Feb-ruary 2023 with CHL, the patient was stratified based on the Ann Arbor staging of Hodgkin lymphoma guidelines by the European Network for Pediatric Hodg-kin Lymphoma (EURONET-PHL). Laboratory and physical examination con-firmed the clinical conditions of peripheral neuropathy and acute pancreatitis, which are adverse effects of chemotherapy, which were managed with IV Pipe-racillin Tazobactam (100 mg/kg) and opioid medications. The European Net-work-Paediatric Hodgkin Lymphoma Study Group (EuroNet-PHL) developed the standard protocol for the first-line therapy of Hodgkin lymphoma in children. Vincristine-induced neuropathy was treated with Morphine (10 mg orally) and Gabapentin (300 mg) was used to provide analgesia. His chemotherapy in-volved two cycles of an OEPA regimen, in accordance with guidelines for the treatment of CHL, and improved clinically. This case report is being offered to clinically enlighten people about the early diagnosis, treatment of CHL and adverse effects of the vincristine drug used in chemotherapy in pediatric pa-tients.

 

Author(s)details:-

 

Krithika Sri J. B.
Gleneagles Global Hospital, Chennai, Tamil Nadu, India.

 

Priyanka N.
Gleneagles Global Hospital, Chennai, Tamil Nadu, India.

 

Please See the book here :- https://doi.org/10.9734/bpi/mria/v6/282

Determination of Pharmacological and Therapeutic Potential of Cissus quadrangularis L. | Chapter 6 | Current Aspects in Pharmaceutical Research and Development Vol. 6

 The goal of this study was to find out how effective Cissus quadrangularis is as a pharmacological and therapeutic agent. L. Cissus quadrangularis(CQ) Linn., also known as Veldt Grape, Winged Tree-bine, or Devil's Backbone, is an Asian and African plant that is endemic to India and Sri Lanka. Numerous studies support the creation of new oncology treatments to be added to existing protocols in order to improve the effectiveness of existing treatments, reduce side effects, and improve patients' quality of life. Chemotherapy-induced side effects are dependent on a number of factors, including the drug used, its dosage, and the length of treatment. Pain, weariness, sore throats and mouths, diarrhoea, nausea, vomiting, constipation, and blood problems are some of the side effects. Chemotherapy can cause cognitive dysfunction, headaches, dizziness, vision loss and vision disturbances such as blurred or double vision, changes in learning and memory, sexual dysfunction, ataxia, and peripheral neuropathy, which are all typical side effects.

Author(S) Details

Sheik Abdulla Shahul Hameed
Department of Chemistry and Biosciences, SASTRA Deemed to be University, Srinivasa Ramanujan Centre, Kumbakonam 612 001, Tamil Nadu, India.

Renuka Saravanan
Department of Chemistry and Biosciences, SASTRA Deemed to be University, Srinivasa Ramanujan Centre, Kumbakonam 612 001, Tamil Nadu, India.

Sivakumar Ramalingam
Department of Chemistry and Biosciences, SASTRA Deemed to be University, Srinivasa Ramanujan Centre, Kumbakonam 612 001, Tamil Nadu, India.

Sampath Kumar Palanisamy
Department of Chemistry and Biosciences, SASTRA Deemed to be University, Srinivasa Ramanujan Centre, Kumbakonam 612 001, Tamil Nadu, India.

View Book:- https://stm.bookpi.org/CAPRD-V6/article/view/5158