Evaluation for the Phytoconstituents, Phytochemical & Pharmacological Investigations of Diospyros malabarica (Desrousseaux) Available in Bangladesh | Chapter 15 | Medical Science: Trends and Innovations Vol. 13

Diospyros malabarica is a prominent member of the Ebenaceae. In Assamese, this medium-sized evergreen tree is referred to as kendu. Many North-East Indian ethnic groupings use the herb for its ethnomedical purposes. The following parts of Diospyros malabarica were used to screen phytochemicals both qualitatively (flavonoids, terpenoids, saponins, tannins) and quantitatively (total phenolic and flavonoid contents). All the parts of Diospyros malabarica were extracted in turn using organic solvents like petroleum ether, dichloromethane, ethyl acetate, ethanol, methanol and water in decreasing order of polarity from less polar to more polar solvents. These solvents included the root, leaves, bark, stem, ripe and unripe fruit. Additionally, biological activities that have antibacterial, antifungal, anticancer, antidiabetic and anti-inflammatory properties were investigated. The results showed that methanol was the best solvent for the extraction, followed by ethanol. It represented the highest extraction yield (18.3%), the richest diversity of phytochemicals and the highest levels of total phenolic and flavonoid contents in bark extract (602 ± 0.001  µg EAG/mg of extract and 455 ± 0.6 µg EQ/mg of extract, respectively). Among various D. malabarica extracts, methanol bark extract had the highest in vitro antibacterial activity (30.25 mm ± 0.9), antifungal activity (18.25 mm ± 0.2), anticancer activity (48%), antidiabetic activity (68%) and anti-inflammatory activity (62%). For this reason, among other extracts of D. malabarica, methanol may be the best solvent to extract the most phytochemicals, promising antioxidants and in vitro biological activities from the bark extract. It may also act as a free radical rummager.

 

Author (s) Details

 

Afnan Sayeid Himi
Department of Pharmacy, University of Asia Pacific, 74/A, Green Road, Farmgate, Dhaka - 1205, Bangladesh.

 

Manik Pramanik
Department of Pharmacy, Jagannath University, 9-10 Chittaranjan Avenue, Dhaka - 1100, Bangladesh.

 

Maisha Muntaher
Department of Pharmacy, University of Asia Pacific, 74/A, Green Road, Farmgate, Dhaka - 1205, Bangladesh.

 

Md. Sagar Mia
Department of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka - 1229, Bangladesh.

 

Md. Ariful Islam
Department of Pharmacy, State University of Bangladesh, Kanchan Bridge, South Purbachal, Dhaka - 1461, Bangladesh.

 

Khadizatul Kubra
Department of Pharmacy, University of Asia Pacific, 74/A, Green Road, Farmgate, Dhaka - 1205, Bangladesh.

 

Khandaker Antara Anika
Department of Pharmacy, State University of Bangladesh, Kanchan Bridge, South Purbachal, Dhaka - 461, Bangladesh.

 

Please see the book here:- https://doi.org/10.9734/bpi/msti/v13/5047

The Impact of Geographical Factors on the Respiratory Health of Workers in the Biri and Tea Gardens Located in West Bengal, India | Chapter 7 | Current Innovations in Disease and Health Research Vol. 6

 The basic aim of this study is to decide the impact of geographical factors on the respiring health of laborers of the biri and tea flowers. Occupational hazards are common among small roll of tobacco and tea garden clerks. Individual physicians might take advantage of using GIS for demographic reasoning to estimate demand for various sorts of services. GIS has helped the healthcare business in the same manner that it has supported other customer service firms in directing assets and stick. The technique included field surveys, shared sessions with workers, lung function testing, dossier input, and the analysis of liberated and dependent dossier, as well as the construction of indexes. Seasonal healing camps with spirometers for pulmonary function testing were grasped. Environmental conditions were studied utilizing air samplers. With enough diversification, the detected and judged issues can be prevented from flattering harmful. The dust from the kendu leaves becomes in the air during bidi manufacturing and is breathed apiece biri binders, moving their health and causing respiring impairments.  Male and female biri binders unprotected to biri binders had poorer pulmonary function test principles than controls of the same sex. Tobacco-unprotected male biri binders had 36.29 % pulmonary degradations, of which 21.77 % were restrictive, 4.03 per insignificant value were obstructive, and 10.48 percent were two together restricted and obstructed. Garden laborers complained of deficiency of breath three times as well industry workers.

Author(s) Details:

Jayati Das,
Shri Shikshayatan College, Kolkata,India.

Saibal Moitra,
Allergy and Asthma Research Centre, Kolkata, India.

Please see the link here: https://stm.bookpi.org/CIDHR-V6/article/view/11841