Fourier Transform Infrared (FTIR) Spectroscopy in Breath Analysis | Chapter 8 | Pharmaceutical Science: New Insights and Developments Vol. 8

There are several potential medicinal and scientific uses for breath analysis, a relatively new field of inquiry. The environment, microorganisms in the gut and airways, and metabolites of ingested precursors all contribute to the body's internal production of volatile organic compounds (VOCs) that are detected in breath. Several recent studies suggest that breath analysis may aid in the diagnosis of illnesses associated with alterations in breath composition. Infrared spectroscopy is a promising analytical method for the metabolic analysis of breath. There are substances in human breath that can be used to assess environmental exposure, diagnose diseases, and monitor physiological conditions. Exhaled breath promotes collaboration and is the ideal biological fluid because it is nearly limitless and causes little to no discomfort for the patient. Breath analysis is a suitable technique for certain applications, as exhaled breath can be captured without the need for medical personnel or privacy, and it typically doesn't produce infectious waste (although airborne infections may be present). Breath analysis is a non-invasive technique that reveals the overall health and condition of the body's metabolism by describing the volatile content of the bloodstream and airways using the volatile composition of exhaled breath (EB). However, because exhaled breath includes relatively little of the metabolites, the absorption strength of the metabolites is still quite moderate. This chapter presents recent applications of the infrared spectroscopic technique published between 2020 and 2025.

 

 

Author(s) Details

Andrei A. Bunaciu
S.C. AAB_IR Research S.R.L., 9-11A Gloriei Street, Bragadiru – Ilfov District, 077025, Romania.

 

Hassan Y. Aboul-Enein
Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Center, Cairo 12622, Egypt.

 

Please see the book here :- https://doi.org/10.9734/bpi/psnid/v8/6146

 

Advancements in Early Disease Diagnosis Using FTIR Spectroscopy of Body Fluid | Chapter 5 | Achievements and Challenges of Medicine and Medical Science Vol. 13

Because of the rising incidence of infectious diseases in the twenty-first century, point-of-care diagnostics are desperately needed. A popular analytical method for examining the vibrational signatures of organic substances is FTIR spectroscopy. It has been used in a wide range of biomedical sectors in recent years due to its ability to identify the molecular structure and content of different biological materials without the usage of probe molecules. Severe shortages in reagents and testing kits have significantly impacted testing for suspected parasite, bacterial, fungal, and viral illnesses. Infrared spectroscopy has been used increasingly to characterize biological matrixes, providing a simple way to obtain diagnostic and observational information from easily acquired samples to monitor some modifications and finally to describe a biological matrix to detect earlier alterations that can generate diseases. Infrared spectroscopy is becoming increasingly useful in the field of biomedical research. This focal point chapter will demonstrate how Fourier transform infrared (FTIR) spectroscopy can identify disease markers in bodily fluids, and significant analytes that are suggestive of illness. This chapter presents some recent applications of the infrared spectroscopic technique published between 2020 and 2025.

 

Author (s) Details

 

Andrei A. Bunaciu
S.C. AAB IR Research S.R.L., 9-11A Gloriei Street, Bragadiru – Ilfov District, 077025, Romania.

 

Hassan Y. Aboul-Enei
Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Center, Cairo 12622, Egypt.

 

Please see the book here:- https://doi.org/10.9734/bpi/acmms/v13/4466