Ozone Therapy in the Management of Trigeminal Neuralgia | Chapter 12 | Medical Science: Trends and Innovations Vol. 3

Trigeminal neuralgia includes a complex of painful, intensely explosive (electric shock-like) manifestation in the oral and maxillofacial area, sometimes accompanied by sweating or local hypersensitivity. Due to the extremely intense neuropathic pain, Trigeminal neuralgia affects the patient’s quality of life. This study presents a case of a 54-year-old patient with hemicrania and hypersensitivity on the right side of the face, who spoke with his mouth almost closed. After 12 sessions of ozone therapy (subcutaneous infiltrations), the pain disappeared, gradually, evaluated by VAS (Visual Analog Scale) and the other symptoms were significantly improved. Ozone therapy is used in chronic diseases, in treating pain, and for rejuvenation purposes, by injections, insuflations, autohemotransfusion and locally applied. Also, ozone therapy presents disadvantages characterized in rare cases by respiratory or neurological complications. However, ozone therapy remains an alternative treatment modality to classic ones.

 

Author (s) Details

Ioana Soare
Primary Care Physician for Medical Expertise and Work Capacity Recovery, Faculty of Medicine, Titu Maiorescu University of Bucharest, Romania.

 

Roxana Mirica
Primary Care Physician for Medical Expertise and Work Capacity Recovery, Carol Davila Medicine and Pharmacy University of Bucharest, Romania.

 

Please see the book here:- https://doi.org/10.9734/bpi/msti/v3/4017

An Overview of Recent Advances on Pathophysiology, Diagnosis and Treatment of Trigeminal Neuralgia | Chapter 04 | New Horizons in Medicine and Medical Research Vol. 2

 Trigeminal Neuralgia (TN) is the most common type of neuropathic face pain, and it has a significant impact on the quality of life of those who suffer from it. The cause of the classic type has been identified as neurovascular conflict (NVC), however TN can be due to various disorders. There is no NVC or other aetiology of TN in the idiopathic form. However, the specific sequence of events and mechanisms that lead to TN remain unknown, although new research suggesting that an inflammatory environment may play a role. The development of novel magnetic resonance imaging (MRI) techniques such as voxel-based morphometry, diffusion tensor imaging, and three-dimensional time-of-flight magnetic resonance angiography has revealed fresh information on the pathophysiology of TN. Furthermore, the use of these enhanced MRI sequences in conjunction with volume-rendering software and neuronavigation techniques had a considerable impact on the surgical outcome of patients undergoing microvascular decompression. TN management is, in fact, pharmacological from the start; nonetheless, TN might gradually grow insensitive to medications, necessitating multimodal treatment. Despite the multiple techniques available, the outcomes are not entirely satisfactory, and the desire for more effective medications led to the development of new compounds and pharmacological procedures. Furthermore, some patients may develop drug resistance, necessitating a surgical surgery or radiation treatment. However, pain recurrence after one or more surgical procedures is common, and other rescue treatments, such as neuromodulation, may be required to manage the symptoms. These observations demonstrate the lack of a thorough understanding of TN pathophysiology. The purpose of this work was to review recent research on pathogenesis, diagnostics, medicinal and surgical treatments, and to discuss major developments in all of these domains.

Author(S) Details

Nicola Montano
Department of Neuroscience, Neurosurgery Section, Fondazione Policlinico Universitario a Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Alessandro Rapisarda
Department of Neuroscience, Neurosurgery Section, Fondazione Policlinico Universitario a Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

View Book:- https://stm.bookpi.org/NHMMR-V2/article/view/6124

A Review on MVD for Trigeminal Neuralgia | Chapter 10 | Highlights on Medicine and Medical Science Vol. 13

 Trigeminal neuralgia (TN) is a type of facial discomfort that is extremely infrequent.

It's characterised by a sudden onset of electric shock-like facial discomfort along the sensory distribution of the fifth cranial nerve.

When PTS symptoms become intractable and medications are no longer effective, patients must seek surgical decompression. Our research will look at the relationship between vascular compression radiologically and during surgery, as well as micro vascular decompression for trigeminal neuralgia and its outcomes, as well as a literature review.

Methods: This is a retrospective analysis of 40 persons diagnosed with TN between July 2009 and July 2015.

MVD has been performed on all of the patients.

Demographic data, clinical presentation, surgical findings, complications, and long-term follow-up were all examined.

The median age of onset of TN is 50.4 years, with five age groups ranging from 24 to 89 years, and a female preponderance of 65.5 percent over men.

In the distribution of location, the right to left ratio was 1.5:1.

There was no evidence of mortality in the study.

Complications occurred in three patients in the study population.

Three patients had facial hyposthesia, one had V3 paresis, and one had CSF otorrhoea, which all improved after LP draining.

All of the patients improved satisfactorily, with the exception of one who experienced persistent discomfort. Conclusions: To summarise, for medically refractory TN patients who are surgically fit, microvascular decompression (MVD) is the surgical technique of choice.

Of all the currently known surgical techniques, MVD has the highest rate of long-term patient satisfaction and the lowest rate of pain recurrence.

Author (S) Details

Renuka S. Melkundi
Department of ENT, GIMS, Kalaburagi, Karnataka, India.

Sateesh Melkundi
Department of Neurosurgery, Mahadevappa Rampure Medical College, Gulbarga, Karnataka, India.

View Book :- https://stm.bookpi.org/HMMS-V13/article/view/2729