Aim: Medicinal plants have potential pharmacological effect
and Screening of natural extracts is a focused intensive study that aims to
find active principles sorted from plant resources both safe and environmental
friendly.
The present study was aimed to evaluate the antibacterial activity of direct
crude extracts of Carica papaya leaves and Allium sativum cloves alone and in
combination against multiple drug resistant strains.
Methods: The antibacterial potency of each plant extract individually and in
combination was evaluated using five bacterial strains causing infections. Two
Gram positive (Staphylococcus aureus and Bacillus cereus) and three strains of
Gram negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa)
bacteria were used to evaluate the antibacterial activity of Carica papaya
leaves and Allium sativum using Agar Disk Diffusion Method.
Results: The results revealed that Carica papaya leaves extract and Allium
sativum cloves extracts were potentially effective in suppressing microbial
growth with variable potency. The combination of extracts of both plants was
found to be most effective combination in retarding microbial growth of all
tested pathogenic bacteria at concentration of 10 mg/disc than individual
extracts.
Conclusion: The extracts have the
potential to serve as natural alternatives for preventing food poisoning and
preserving food while avoiding the potential health risks associated with the
use of chemically antibacterial agents.
Author(s) Details:
Srividya Lonkala,
Department of Pharmaceutical Sciences, Beside LMD Police Station,
Thimmapur, Karimnagar-505481, Telangana, India.
Prasadaswamy
Thirunahari,
Department
of Pharmaceutical Sciences, Beside LMD Police Station, Thimmapur,
Karimnagar-505481, Telangana, India.
Please see the link here: https://stm.bookpi.org/ACPR-V7/article/view/13776
