Steroidal Saponins Isolated and Purified from Leaves Extract of Asparagus racemosus (Family – Asparagaceae) and its UV, IR, NMR and Mass Spectrum Analysis | Chapter 8 | Advanced Concepts in Pharmaceutical Research Vol. 6

Asparagus racemosus is an important medicinal plant Its medicinal usages has been reported in Indian and British pharmacopoeias. Herbs made by the Asparagus racemosus are highly effective in problems which related with female reproductive system and other diseases. The Fresh plant leaves were collected from Govt. Science & Commerce College, Benazir, Bhopal (M.P.) in July-September 2012. Qualitative preliminary phytochemical analysis was performed on the crude extract for the presence of bioactive compounds. The pure compound isolated to the Column chromatography and purified this compound by Thin Layer Chromatography with suitable solvent systems and visualizing reagents.

Structure elucidation of pure compound has been accomplished through the extensive use of UV-Visible, IR, 1HNMR and Mass spectroscopy. Isolated compound was gave a positive test Liebermann-Burchard test for steroidal saponin and the compound obtained as dark brownish amorphous powder as a single spot with 0.37 Rf value. Phytochemistry and spectral analysis showed the presence of steroidal saponin in Asparagus racemosus leaves extract. It is strongly believed that the phytochemical and various biological properties of the extracts might provide detailed evidence for the use of this plant in different medicines.

Author(s) Details:

Namrata S. Rajawat,
Department of Applied Chemistry, SATI, Vidisha (M.P), India.

Please see the link here: https://stm.bookpi.org/ACPR-V6/article/view/13466

Hyphenated Technique - Thermogravimetry-Differential Scanning Colorimetry Coupled to Mass Spectroscopy| Chapter 4 | Research Highlights in Science and Technology Vol. 4

 A thermo-examining approach which is known as thermogravimetric reasoning uses weight changes that occur whena sample is warmed to a consistent pace to confirm a material thermal balance & percentage of the doubtful additives present. DSC analysis is secondhand for measuringa variety of quantities, including softening temperature, hidden melting warmth, melding warmth, reaction capacity, and many more.Mass spectrophotometry is a potent analytical finish containing abundant uses in the biomedical & pharmaceutical industries. A maneuver's increased sensitivity and judgment have opened up new avenues for the test of prescribed medications and complex basic structure metabolites. The synthetic properties and thermal balance of plant-based polymers isolated from chemically singular soils were revealed using thermogravimetry as well DSC, quadrupole mass spectrometry, and added techniques. TGA/DSC, when used together along with MS, isolates several ions from the pattern substitute in accordance with a specific bulk-to-charge ratio.The connected instrument is used to evaluate the powder covering's physical characteristics and shame balance while also identifying basic components.

Author(s) Details:

K. Bhavyasri,
Department of Pharmaceutical Analysis, RBVRR Women’s College of Pharmacy, Barkatpura, Hyderabad-500027, India.

Please see the link here: https://stm.bookpi.org/RHST-V4/article/view/10910