Results of a Comparative Study on Fast Superposition, Superposition Algorithm in Intensity Modulated Radiotherapy Techniques for Prostate Cancer | Chapter 7 | Current Topics in Medicine and Medical Research Vol.5

 

This study aims to compare the dosimetric coverage of the Planning Target Volume (PTV) and the
dose to main organs at risk (OARs) between two dif-ferent algorithms fast superposition (FSUP),
superposition (SUP) using in-tensity-modulated radiotherapy (IMRT) techniques for prostate cancer.
Ten patients with prostate cancer were selected for this study. For each patient, IMRT plans were
created with 6 MV photon beam quality using CMS XiO treatment planning system. The delivery of
IMRT was carried out using the step and shoot techniques. The dose coverage for each patient was
designated to an ICRU report 62 reference point in the PTV, medium coverage of the planned target
volume to be 95% of the prescribed dose while the maximum dose in the target volume to be not
greater than 107% of the prescribed dose. A hypofractionated prescription dose of 70 Gy/28# at 2.5
Gy per fraction was used. For target, this evalua-tion was made with comparing the conformity index
(CI) and homogeneity index (HI). The results of the present study showed the OARs got less dose
from the SUP algorithm compared to FSUP algorithms. Statistically not significant difference was
observed in V107% of PTV, MU/CC, conformity Index (p = 0.057, p = 0.215, p = 0.370) and 95% PTV
Volume received prescription dose from both Plans. For prostate cancer, the superposition algorithm
showed better results in the IMRT plan compared to the fast superposition algorithm.

Author (s) Details

Dr. Mukesh Zope
Department of Medical Physics, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, India.

Dr. Deepali Patil
Department of Medical Physics, State Cancer Institute, Indira Gandhi Institute of Department of Radiation Oncology, Paras HMRI Hospital, Patna, India.

Angel Kuriakose
Department of Radiotherapy, Mahavir Cancer Sansthan, Patna, India.

P. A. Aslam
Department of Radiotherapy, Mahavir Cancer Sansthan, Patna, India and Speciality of Medical Physics, Super Speciality of Cancer Institute and Hospital, Lucknow, India.

Basil George
Department of Radiotherapy, Regional Cancer Care Center and Cancer Hospital, Siddhpur, India.

Abhijit Mandal
Department of Radiotheraphy & Radiation Medicine, Institute of Medical Sciences, Varansi, India.

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Dosimetric Analysis of Three Different Sets of Five Fields and Seven Fields IMRT Plans for Prostate Cancer: Comparative Study | Chapter 9 | Current Topics in Medicine and Medical Research Vol.5

 

The advent of Intensity Modulated Radiation Therapy (IMRT) is rapidly changing the field of Radiation
Oncology. IMRT has the potential to improve clinical implementation of highly conformal non-convex
dose distributions. The ability of IMRT to reduce dose to nearby normal structures without sacrificing
dose coverage of the target makes it an ideal treatment modality for prostate cancer. Nonetheless, a
number of IMRT approaches including coplanar and noncop-lanar beam techniques with 5 to 9
beams at different angles have been used in an effort to get the best dose distribution. The purpose
of this study is to compare the dose to normal tissue and dose-limiting structures, conformity index,
homogeneity index, number of monitor units required for the treatment of prostate cancer in 3 sets of
five and seven beam IMRT plans and thus to select the best IMRT approach for patients with prostate
cancer.

Author (s) Details

Dr. Mukesh Kumar Zope
Department of Medical Physics, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, India.

Dr Deepali  Bhaskar  Patil
Department of Medical Physics, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, India and Department of Radiation Oncology, Paras HMRI Hospital, Patna, India.

Angel Kuriakose
Department of Radiotherapy, Mahavir Cancer Sansthan, Patna, India.

Aslam Rahman
Department of Radiotherapy, Mahavir Cancer Sansthan, Patna, India and Speciality of Medical Physics, Super Speciality of Cancer Institute and Hospital, Lucknow, India.

Vinita Trivedi
Department of Radiotherapy, Mahavir Cancer Sansthan, Patna, India.

Shekhar Kumar Keshri
Department of Radiation Oncology, Paras HMRI Hospital, Patna, India.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/270