An Overview of IgA Vasculitis (Henoch- Schönlein Purpura) among Children | Chapter 4 | Advanced Concepts in Medicine and Medical Research Vol. 6

 This unit discusses about IgA Vasculitis (Henoch- Schönlein purpura) among babies. The IgA vasculitis, a primary vasculitis that generally affects small ancestry vessels, is analyzed based on the presence of characteristic purpura or petechiae, intestinal discomfort, and renal abnormalities. The Ig A vasculitis is an severe multisystemic disease with signs and manifestations of purpura or petechiae, arthralgia or arthritis, and abdominal pain. Nearly 50% to 75% of children have gastrointestinal symptoms, to a degree colicky abdominal discomfort, disgorging, paralytic ileus, and GI bleeding, frequently occurring betwixt 1-4 weeks. An incomplete presentation of IgAV, specifically if the skin symptoms are originally missing or there is an nonconforming presentation, the disease becomes very difficult. If, it is necessary to allow for possibility alternative factors that may influence purpura, arthritis, abdominal discomfort, and renal ailment. Disease recurrence can happen in patients accompanying IgA Vasculitis even after renal transplantation. But despite current advances in molecular understanding and healthcare conveniences over the last few decades, the renal complication of IgA vasculitis remains a concern and the consequence has not changed over occasion.

Author(s) Details:

Chinmay Kumar Behera,
Department of Pediatrics, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Reshmi Mishra,
Department of Pediatrics, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Please see the link here: https://stm.bookpi.org/ACMMR-V6/article/view/12640

Management of Henoch-Schonlein Purpura Treated with Oral Steroids | Chapter 7 | Current Practice in Medical Science Vol. 1

A 38-year-old man with irritable bowel syndrome (IBS) visited the clinic complaining of acute rash and severe central abdominal discomfort. The day before visiting the clinic, the patient visited the Emergency Department (ED) with the same problems. The patient described the pain in his or her stomach as colicky. He had an upper respiratory tract infection three weeks before, during which he started to have these symptoms. However, there were no further symptoms, such as nausea, vomiting, or GI bleeding. He received medical attention for his condition, which immediately got better. The ED staff investigated the reason and ran a contrast-enhanced CT abdomen, but all of the results were negative. His serum creatinine level was somewhat high at the time. The patient's abdomen was quite painful during a clinical examination. He had a large, crimson, raised rash that was purpuric in colour that covered both of his hips and lower limbs. Up to the forearms, the upper limbs were also engaged.

All of the patient's lab tests, including the CBC, creatinine, serum C3, C4, and rheumatoid factor, were normal. Positive occult blood was discovered in the patient's stool, and CRP was discovered to be high.

Using a combination of the aforementioned medical symptoms and tests, the patient's condition was determined to be abdominal angina. The symptoms were consistent with the usual pattern: purpuric rash, stomach discomfort, involvement of the kidneys, occult blood in the stool, all of which were preceded by a confirmed upper respiratory tract infection (URTI). The patient was eventually diagnosed with immune-mediated IgA vasculitis (also known as Henoch-Schonlein purpura) and received treatment as a result.

In the parts that follow, we'll look at how the patient was identified, treated, and managed appropriately to preserve his life. As a result, this case will serve as crucial study material for all interested physicians and doctors, enabling them to prepare for the possibility that they could face a patient like this in a clinical context. The example explains how uncertainties should be handled when facing such perplexing instances by thoroughly examining all the factors that contributed to the patient's final diagnosis.

Author(s) Details:

Mohamed Eltaieb Ali,

Department of Internal Medicine, Madinat Zayed Hospital, UAE.

Ashraf Alakkad,

Department of Internal Medicine, Madinat Zayed Hospital, UAE.

Please see the link here: https://stm.bookpi.org/CPMS-V1/article/view/7326

Endoscopic Management of Upper GI Bleed: A Review | Chapter 10 | Highlights on Medicine and Medical Science Vol. 8

 Upper gastrointestinal haemorrhage is a frequent condition that affects people all over the world, with an estimated yearly incidence of 40-150 cases per 100,000 people. Several risk stratification scores have been established to improve clinical decision-making for urgent intervention and triage patients to in-hospital vs. out-of-hospital care. Glasgow Blatchford Score (GBS) and Rockwall Score were the two most generally validated scores. Patients who had endoscopy after 24 hours had a higher mortality rate, according to a retrospective examination of almost 400 000 patients with NVUGIB. Cyanoacrylate (CYA) Spray is a spray treatment that can be used as an alternative to surgery for excessive GI bleeding in emergency situations.

Author (s) Details

Hallal Mahmoud
Department of Gastroenterology and Hepatology, AlZahraa University Medical Center, Beirut, Lebanon.

Matar Rasha
Department of Gastroenterology and Hepatology, AlZahraa University Medical Center, Beirut, Lebanon.

Sanyour Joyce
Department of Gastroenterology and Hepatology, AlZahraa University Medical Center, Beirut, Lebanon.

View Book :- https://stm.bookpi.org/HMMS-V8/article/view/2170