The laboratory examination performed through blood tests is an important aspect of diagnosing thyroid problems. In order to choose the best treatment options for thyroid disease patients and improve workflow and efficiency, a trustworthy and precise diagnosis is required. Because of the increased late diagnosis of thyroid disease in patients with diverse thyroid problems, this study was conducted. As a result, the goal of this chapter is to introduce concepts related to thyroid illness diagnosis.
Objective: The goal of this study was to determine the use of fT3 and fT4 in the diagnosis of various thyroid disorders. Medical professionals who treat thyroid illnesses require the right tools to deal with their patients' issues. Free thyroxine (fT4) and free triodothyronine (fT3) were calculated and utilised as indices for the differential assessment of thyroid function. Between February 2010 and April 2013, nine hundred and seven (907) people were diagnosed with various thyroid dysfunctions at various hospitals and clinics in Port Harcourt, Rivers State, Nigeria. The investigation was carried out using the enzyme linked immuno sorbent assay (ELISA) method. 532 of the 907 patients were females, accounting for 58.65% of the total, while 375 were males, accounting for 41.35 percent. According to the findings, 55.46 percent of patients diagnosed with primary hyperthroidism had elevated serum levels of both total and free T3, T4 with low TSH values, while 3.09 percent of hyperthyroid cases had normal total T4 and T3 but elevated values of fT4 and fT3. 0.88 percent of patients diagnosed with hypothyroidism had normal total T4 and T3 but low serum levels of fT4 and fT3, and were diagnosed clinically. In 9.81 percent of the patients, triiodothyronine (T3) toxicosis was observed, with high fT3 and normal fT4 serum levels. 9.26% of individuals with non-thyroidal disease had low serum fT4 levels. In addition to high blood TSH levels, two patients (about 0.22 percent) with TSH Secreting Tumors exhibited an elevated serum fT4 level. This study discovered that fT3 and fT4 can be used as a diagnostic tool for thyroid problems.Author(S) Details
F. C. Ezeiruaku
Department of Medical Laboratory Science, Collage of Health Sciences, Niger Delta University Wilberforce Island, Bayelsa State, Nigeria.
D. C. Ukaji
Faculty of Medical Laboratory Science, Madonna University, Elele, Rivers State, Nigeria.
E. M. Eze
Faculty of Medical Laboratory Science, Madonna University, Elele, Rivers State, Nigeria.
C. U. Okeke
Department of Prosthesis and Orthopaedic Technology, Federal University of Technology Owerri, Imo State, Nigeria.
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