Nanoparticles as a Delivery System for Conventional drugs and Herb-Derived Compounds for Cancer Therapy| Chapter 8 | Challenges and Advances in Pharmaceutical Research Vol.3

The purpose of this paper is to look at how pharmacokinetic studies of nanoparticles loaded in conventional pharmaceuticals and herb-derived chemicals can be used to treat cancer. The pharmacokinetic features of many herbal medicines and chemotherapeutic drugs integrated into nanoparticles were studied. The AUC of the plasma concentration-time profile, the maximum plasma concentration (Cmax), the time to maximum plasma concentration (Tmax), the volume of distribution (Vd or Vss), the elimination half-life (t 12), and clearance were all included (CL). Until February 2019, the systematic review was conducted utilising the PubMed and Science Direct databases. According to this systematic study, polymeric nanoparticles were the most extensively used nanocarrier to enhance pharmacokinetic properties. As a revolutionary drug delivery technique, nanoparticles have the potential to enhance the pharmacokinetics and cytotoxicity of loaded drugs/herb-derived substances for cancer treatment.

Author(s) Details:

Abdifetah Ibrahim Omar,
Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand and Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.

Nadda Muhamad,
Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand and Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.

Tullayakorn Plengsuriyakarn,
Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand and Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.

Kesara Na-Bangchang,
Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand and Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand and Drug Discovery Center, Thammasat University, Pathumthani, Thailand.

Please see the link here: https://stm.bookpi.org/CAPRV-3/article/view/6948

Determining the Use of Traditional Medicines by Traditional Healers in the Bapedi Society to Prevent and Cure Different Health-Related Problems or Ailments | Chapter 09 | Emerging Trends in Disease and Health Research Vol. 1

 Traditional healers in the Greater Sekhukhune District Municipality in South Africa's Limpopo province value the conservation of farm and garden flora. These plants are employed in both rituals and medicine. These plants' leaves, barks, and roots are used to treat a variety of health problems and maladies. The current study looked into topics of interest and historical significance in the Bapedi society's traditional healers' philosophy of traditional healing practise. Oral interviews were the primary source of information. Observations, publications, and records were used as secondary sources. Video recordings and photography of various farm and garden plants, as well as traditional medicines utilised by traditional healers in their therapeutic practise, were among the other methods used. As a result, this study was led by the following interrelated research questions: 1) Is there enough interest among Bapedi people in traditional medicines and treatment methods? 2) Are traditional medicines beneficial to both traditional healers and Bapedi people? 3) Do traditional medicinal plants have the potential to meet Bapedi people's diverse health care needs? 4) What is the cultural significance of traditional healing in Bapedi society today? The findings revealed that a high majority of Bapedi people seek traditional healers for survival, as well as to enhance their indigenous beliefs and practises and maintain their traditional lifestyle. Traditional remedies appear to benefit both traditional healers and Bapedi people, according to this study, by incorporating their way of life and living environment. It was concluded that natural resource conservation, such as garden and farm plants, should be taken seriously, because the use of some of these indigenous medicinal plants has been shown to treat a wide range of health problems or ailments, and has the potential to meet the diverse health care needs of the Bapedi people.

 
Author(S) Details

Morakeng Edward Kenneth Lebaka
Department of Creative Arts, Faculty of Arts, Kwa Dlangezwa Campus, University of Zululand, South Africa.

View Book:- https://stm.bookpi.org/ETDHR-V1/article/view/5210