Malignant Peritoneal Mesothelioma Presenting with Unresolving Haemorrhagic Ascites: A Case Report | Chapter 12 | Medicine and Medical Research: New Perspectives Vol. 3

Aim: We report a case of malignant peritoneal mesothelioma presenting with persistent haemorrhagic ascites.

 

Background: Peritoneal mesothelioma being a rare tumour, is difficult to diagnose and start treatment. The most common site for mesothelioma is the pleura, which is followed by the peritoneum as the second most common site. In certain instances, synchronous pleural and peritoneal mesotheliomas are seen (around 30–45% of cases). Because mesothelioma may not always show with particular symptoms or clinical findings, diagnosis can be challenging. In addition, in the absence of previous asbestos exposure, a delay in the diagnosis takes place. Here we report a case of malignant peritoneal mesotheliomas. The diagnostic and therapeutic approaches for these rare neoplasms are discussed.

 

Presentation of Case: We present a case of a 24-year-old male patient with complaints of pain abdomen (on and off) and abdominal distension for 15 days, with no inhalational exposure to asbestos, causing diagnostic confusion. He had a prior history of persistent haemorrhagic ascites, with no drug allergy. A diagnostic laparoscopy was done, showing multiple omental nodules. Omental biopsy along with immunohistochemistry leads to diagnosis of malignant peritoneal mesothelioma.

 

Discussion and Conclusion: Clinical cases of peritoneal mesotheliomas are uncommon. However, peritoneal mesotheliomas should be evaluated as one of the differential diagnoses for individuals presenting with chronic abdominal pain and ascites. Diagnosis is often overlooked by radiological investigations. Thus, a thorough clinical assessment and an extensive approach are needed to diagnose and properly treat potential patients with peritoneal mesotheliomas.

 

Author(s) Details

 

Khushboo
Department of Pathology and Lab Medicine, Medanta Hospital, Ranchi, Jharkhand, India.

 

Bikash Kumar
Department of Pathology and Lab Medicine, Medanta Hospital, Ranchi, Jharkhand, India.

 

Ramesh Chandra
Department of Gastroenterology, Medanta Hospital, Ranchi, Jharkhand, India.

Vinay Mishra
Department of General and Minimal Invasive Surgery, Medanta Hospital, Ranchi, Jharkhand, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mmrnp/v3/1889

A Case of Pediatric Kyrle-Flegel Disease in a 6-Year-Old Yemeni Girl | Chapter 10 | Disease and Health Research: New Insights Vol. 5

 

Kyrle’s disease (KD) and Flegel’s disease (FD) are rare variants of primary perforating dermatoses, characterized by transepidermal elimination of abnormal endogenous materials. In 1916, the Austrian dermatologist Josef Kyrle described multiple hyperpigmented papules and nodules 5–10 mm in size with a central keratotic plug in a 22-year-old diabetic woman. On the other hand, Flegel disease is considered a genodermatosis with autosomal dominant inheritance, manifesting in the third to fourth decade of life, although it has been reported in patients as young as 13 years of age. We describe a 6-year-old Yemeni girl with a 2-year history of generalized asymptomatic, small, reddish-brown keratotic papules with a lenticular central keratotic plug. The patient exhibited the clinical characteristics of FD; i.e., generalized small lesions mainly over the face, trunk, and extensor surfaces of the extremities, rather than the large lesions typically observed in KD. Although these features are synonymous with FD, the histology of a punch biopsy was consistent with KD. The patient was otherwise healthy, and no family members had a history of similar diseases. The patient was diagnosed with KD-FD, owing to the manifestation of features associated with both diseases. This case supports the hypothesis that KD and FD are different manifestations or at least represent different stages of the same disease.

 

Author (s) Details

Mohammad Ali Alshami
Dermatology Department, University Hospital, Sana’a University, Sana’a, Yemen.

 

Mona Jameel Mohana
Dermatology Department, University Hospital, Sana’a University, Sana’a, Yemen.

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrni/v5/2072

Outcomes of Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA): Experience from a Single Center in Iraq| Chapter 10 | Perspective of Recent Advances in Medical Research Vol. 3

 Transoral endoscopic thyroidectomy vestibular approach (TOETVA); is a transluminal everyday orifice medical procedure, truly scar free and includes minimal postmortem, thus happening in excellent beautifying results in comparison to conventional open thyroidectomy and different endoscopic thyroidectomy procedures. This stage aimed to interpret the outcome, patient delight, and complications afterwards hemithyroidectomy for benign thyroid knots by TOETVA in comparison accompanying the open approach. This study was conducted in Al-Shiffa General Hospital, Basrah, Iraq from August 2017 to June 2019. Fifty inmates with favorable thyroid nodules the one are candidates for hemithyroidectomy were contained in the study; they were divided into two groups in accordance with the method for thyroidectomy which was either unoriginal open or TOETVA based on the patient's inclinations. The results of this study demonstrated that 24 (48%) of them were conducted upon by TOETVA, while the remaining 26 (52%) sufferers have been conducted upon by the open thyroidectomy approach. TOETVA stated a longer mean event of surgery distinguished to open thyroidectomy (93±8.34 min.) and (48±7.45min.).  It stated a higher rate of vindication scores in bodily pain (BP), social functioning (SF), and role-heated (RE), (99.7±0.21), (99.8±0.10) and (99.6±0.13) compared to (78.4±0.22), (44.8±0.64) and (77.3±0.43) for open thyroidectomy. Two cases of transitory recurrent laryngeal nerve friendly were reported in this place study. 1(4.16%) case was in TOETVA and 1(3.84%) case was in open thyroidectomy. Other reported difficulties in this study that were unique for TOETVA, were interim mental nerve friendly in 1 case (4.16 %), cervical subcutaneous emphysema in 1 case (4.16%), and conversion to open thyroidectomy in 1 case (4.16%).In conclusion, the transoral endoscopic thyroidectomy vestibular approach is a secure and feasible process with an superior cosmetic consequence and better patient satisfaction. At present, it is a relatively behind procedure and, thus, candidate cases with a forceful motivation for scar-free enucleation are recommended.

Author(s) Details:

Sadq Ghaleb Kadem,
Department of Surgery, Al-Shiffa General Hospital, Basrah, Iraq.

Sabah Abdulsahb Mohamd,
Department of Surgery, Al-Shiffa General Hospital, Basrah, Iraq.

Zainab Taher Ibrahim,
Department of Radiology, Al-Shiffa General Hospital, Basrah, Iraq.

Please see the link here: https://stm.bookpi.org/PRAMR-V3/article/view/9069