The Impact of Climate Change on Waterborne Microbial Diversity and Dysbiosis in Carcinogenesis of Indian Sundarbans Fisherpersons: A Review | Chapter 9 | Research Advances in Environment, Geography and Earth Science Vol. 2

Fishing is one of the employment-generating as well as fastest growing sectors and has an important role in socio-economic development in India. Approximately 4 lakh fishermen directly, and 6 lakhs indirectly engage and depend on this industry in West Bengal. Indian Sunderbans lies in North & South 24 Parganas districts and has faced major cyclone shocks of Amphan, Bulbul, Yaas, and Fani within a span of the last 5 years and huge cultivable and livable areas went into the water. Recent reports reveal that these 2 districts have the highest cancer registry in West Bengal. Fishing involves physical hazards, chemical hazards, and biological hazards and it is of national interest to estimate post-climate change chemical and biological effects on affected fisherpersons.
 
Our project would look into pre and post-climate change data from primary health centers and identify affected areas and fisherpersons following questionnaires and health checkups. Reported occupational health hazards and precancerous lesions from the affected population will be further analyzed along with the quality of water-in-use or contact, and residing pathogenic or carcinogenic microbes whether correlated with dysbiosis, direct or zoonotic pathogenesis, etc. This will be the first of a kind of work connecting affected fisherpersons, the quality of their used waterbodies affected by climate change, the rising cancer scenario, and occupational health hazards in Indian Sundarbans. Climate anomalies (salinity, anoxic conditions, and temperature) in waterbodies favor pathogens to grow rapidly that affect fisherperson’s health through opportunistic invasion directly or through zoonotic transmission resulting in waterborne diseases.  Such waterborne infection is linked to increased gastric and gynecological cancer risk by dysbiosis of gut microbiota (producing toxins and metabolites). The goal of this review paper is to suggest a baseline regarding the alteration of climate that may induce factors of dysfunction that may prevalence of cancer (skin, uterine, gastric) in fishermen who are in direct contact with saline water.

Author(s) Details:

Sanjib Saha,
Vidyasagar College for Women (University of Calcutta), 39, Sankar Ghosh Lane, Kolkata – 700009, West Bengal, India.

Biswarup Basu,
Department of Neuroendocrinology & Experimental Haematology, Chittaranjan National Cancer Institute, (Ministry of Health and Family Welfare, Govt of India), 37, S. P. Mukherjee Road, Kolkata-700 026, India.

Please see the link here: https://stm.bookpi.org/RAEGES-V2/article/view/14357

Keywords: Climatic change, Sunderbans, fisherpersons, occupational health hazards, microbial dysbiosis, zoonotic transmission, carcinogenesis

Nutrigenomics and Microbiomics, Contrasting Interpretations of Dismetabolic Diseases | Chapter 11 | Research Aspects in Biological Science Vol. 4

 

In this paper, we examined current interpretations based on Nutrigenomica and Microbiomic research, according to which, at the root of many pathological and dismetabolic manifestations, there'd be or variations of single nucleotide polymorphisms (Snps) in the Nutrigenomic perspective, or modifications in the normal gut microbiota in the Microbiomic perspective.We have examined rigorously the singular pathogenic coincidence, which raises questions about Snps mutations or the presence of specific Microbiota changes for the same illnesses.

As a result, other possible causes of detected disorders are overlooked.
We will give an alternative understanding of pathogenic causes based on the research reviewed.

Author(s) Details:

Bruno Riccardi,
Representative Lipotech, 56022 Castelfranco di Sotto (PI), Via dei Lazzeri, 33, Italy.

Sergio Resta,
Freelancer, 53043 Chiusi (SI), Via Montegrappa 1, Italy.

Giacomo Resta,
Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Perugia, Italy.

Please see the link here: https://stm.bookpi.org/RABS-V4/article/view/7594

New Interpretations of Nutrigenomics and Microbiomics | Chapter 3 | Recent Progress in Microbiology and Biotechnology Vol. 7

 In this paper, we examine current interpretations based on Nutrigenomica and Microbiomics studies, according to which, at the root of many pathological and dismetabolic manifestations, there would be or variations of single nucleotide polymorphisms (Snps) in the Nutrigenomic perspective, or changes in the normal gut microbiota in the Microbiomic perspective.

We examine critically the single pathogenic coincidence, which raises questions about Snps mutations or the presence of specific Microbiota changes for the same illnesses.

As a result, other plausible causes of detected disorders are overlooked.

We propose a distinct understanding of pathogenic aetiology based on the literature reviewed. Nutrigenomic study focuses solely on variations in genetic polymorphisms, while Microbiomic research focuses solely on changes in the intestinal microbiome, with the goal of determining their implications on health.

Author (S) Details

Bruno Riccardi
Castelfranco di Sotto (PI), Via dei Lazzeri, Italy.

Sergio Resta
Department of Surgery, General Surgery Specialist, Freelancer, 53043 Chiusi (SI), Via Montegrappa, Italy.

Roberto Fabbroni
Roberto Fabbroni, Scientific Director of I.B.I. ( Istituto di Biofisica Informazionale), Italy.

View Book :- https://stm.bookpi.org/RPMB-V7/article/view/2573