Theoretical Investigation of Properties of Indoline-2,3-dione-3-oxime Using Chemicalize Software | Chapter 9 | Recent Developments in Chemistry and Biochemistry Research Vol. 6

Indoline-2,3-dione-3-oxime (IDOX) (Isatin-3-oxime) is employed as an anticonvulsant and is known for treating various disorders caused by the release of amino acids responsible for anxiety and excitatory behavior. With the application of chemicalize software of Chemaxon the structure and properties of IDOX were studied. In view of the biological importance of IDOX Properties, pka, Isoelectric Point, logP, logD, Solubility, Geometry, and HNMR were determined by using Chemicalize software and the data obtained was interpreted. Information about Structural details of Indoline-2,3-dione-3-oxime (IDOX) and pka value so obtained indicated the presence of one dissociable proton in IDOX.

 

Author (s) Details

K. Laxmi

Department of Chemistry, Chaitanya Bharathi Institute of Technology (CBIT), Gandipet, Hyderabad -500 075, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rdcbr/v6/2542

Determining the Properties of Phenobarbital an Antiepileptic Drug Using Chemcalise Software | Chapter 03 | Challenges and Advances in Chemical Science Vol. 6

 Barbiturate-class medications are used to treat some disorders, such as insomnia (difficulty sleeping), and to control certain seizures. Phenobarbital is an example of a medicinally important chemical. It's also renowned for its anticonvulsant, antidepressant, and antihypnotic properties [1]. Phenobarbital is used to treat seizures, and its structure is being investigated with the goal of making the medicine more inexpensive, with a wider spectrum of action, and ease of administration. It is regarded the most effective antiepileptic medicine and is utilised as a nonselective central nervous system depressant because of these benefits. Because of the therapeutic value of phenobarbital [1-3]. Chemaxon's chemcalise software was used to investigate its structure and characteristics, and the results were interpreted.

Author(S) Details

K. Laxmi
Department of Chemistry, Chaitanya Bharathi Institute of Technology (CBIT), Hyderabad, India.

View Book:- https://stm.bookpi.org/CACS-V6/article/view/4349